Annotation Detail for BCAR1
Basic Information Top
| Gene Symbol: | BCAR1 ( CAS,CAS1,CASS1,CRKAS,FLJ12176,FLJ45059,P130Cas ) |
|---|---|
| Gene Full Name: | breast cancer anti-estrogen resistance 1 |
| Band: | 16q23.1 |
| Quick Links | Entrez ID:9564; OMIM: 602941; Uniprot ID:BCAR1_HUMAN; ENSEMBL ID: ENSG00000050820; HGNC ID: 971 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.479747
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 13 / 70761 | 183 |  |
| blastocyst | 10 / 62319 | 160 | |
| fetus | 22 / 564012 | 39 |  |
| neonate | 4 / 31097 | 128 | |
| infant | 2 / 23620 | 84 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 158 / 1939121 | 81 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 32 / 82823 | 386 |  |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 16 / 119369 | 134 | |
| germ cell tumor | 23 / 263845 | 87 | |
| glioma | 15 / 106883 | 140 | |
| head and neck tumor | 12 / 136302 | 88 | |
| kidney tumor | 7 / 68959 | 101 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 13 / 103127 | 126 | |
| lymphoma | 4 / 71755 | 55 | |
| non-neoplasia | 10 / 97250 | 102 | |
| normal | 278 / 3360307 | 82 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 11 / 104616 | 105 | |
| primitive neuroectodermal tumor of the CNS | 11 / 125680 | 87 | |
| prostate cancer | 6 / 102680 | 58 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 12 / 124949 | 96 | |
| soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
| uterine tumor | 6 / 90257 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 5 / 40015 | 124 | |
| bladder | 3 / 29757 | 100 | |
| blood | 0 / 123478 | 0 | |
| bone | 14 / 71655 | 195 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 104 / 1100989 | 94 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 12 / 149255 | 80 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 33 / 215722 | 152 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 28 / 211054 | 132 | |
| heart | 1 / 89626 | 11 | |
| intestine | 16 / 234472 | 68 | |
| kidney | 13 / 211777 | 61 | |
| larynx | 1 / 24145 | 41 | |
| liver | 3 / 207743 | 14 | |
| lung | 54 / 336974 | 160 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 7 / 102051 | 68 | |
| pancreas | 16 / 214812 | 74 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 33 / 280825 | 117 | |
| prostate | 7 / 189345 | 36 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 24 / 210574 | 113 | |
| spleen | 6 / 53952 | 111 | |
| stomach | 10 / 96619 | 103 | |
| testis | 36 / 330442 | 108 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 7 / 47473 | 147 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 15 / 232878 | 64 | |
| vascular | 5 / 51780 | 96 | |
Microarray in - Probe name: CUST_16161_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.52 ± 0.41 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.3 ± 0.2 | |
| Basal Part of Pons | 5.89 ± 0.21 | |
| Cerebellar Cortex | 6.26 ± 0.35 | |
| Cerebellar Nuclei | 6.57 ± 0.24 | |
| Claustrum | 6.78 ± 0.26 | |
| Epithalamus | 6.61 ± 0.39 | |
| Frontal Lobe | 6.38 ± 0.39 | |
| Globus Pallidus | 6.44 ± 0.27 | |
| Hypothalamus | 5.89 ± 0.35 | |
| Insula | 6.19 ± 0.34 | |
| Limbic Lobe | 6.31 ± 0.5 | |
| Mesencephalon | 6.18 ± 0.44 | |
| Myelencephalon | 6.43 ± 0.43 | |
| Occipital Lobe | 6.85 ± 0.58 | |
| Parietal Lobe | 6.51 ± 0.39 | |
| Pontine Tegmentum | 6.53 ± 0.39 | |
| Striatum | 6.27 ± 0.42 | |
| Subthalamus | 5.9 ± 0.34 | |
| Temporal Lobe | 6.26 ± 0.43 | |
| Thalamus | 6.51 ± 0.48 | |
| White Matter | 6.25 ± 0.25 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Bcar1 | CB | Cerebellum | 29.38 | |
| 100 | | |||
| Bcar1 | CTX | Cerebral cortex | 44.01 | |
| 34.18 | | |||
| Bcar1 | HIP | Hippocampal region | 38.17 | |
| 53.27 | | |||
| Bcar1 | HPF | Hippocampal formation | 35.62 | |
| 40.87 | | |||
| Bcar1 | HY | Hypothalamus | 22.35 | |
| 17.37 | | |||
| Bcar1 | LSX | Lateral septal complex | 22.39 | |
| 16.07 | | |||
| Bcar1 | MB | Midbrain | 21.34 | |
| 20.09 | | |||
| Bcar1 | MY | Medulla | 39.14 | |
| 44.55 | | |||
| Bcar1 | OLF | Olfactory bulb | 49.87 | |
| 44.54 | | |||
| Bcar1 | P | Pons | 28.55 | |
| 30.55 | | |||
| Bcar1 | PAL | Pallidum | 18.11 | |
| 15.85 | | |||
| Bcar1 | RHP | Retrohippocampal region | 31.63 | |
| 24.78 | | |||
| Bcar1 | sAMY | Striatum-like amygdalar nuclei | 10.57 | |
| 8.41 | | |||
| Bcar1 | STR | Striatum | 19.18 | |
| 14.41 | | |||
| Bcar1 | STRd | Striatum dorsal region | 18.75 | |
| 14.61 | | |||
| Bcar1 | STRv | Striatum ventral region | 24.48 | |
| 16.31 | | |||
| Bcar1 | TH | Thalamus | 26 | |
| 23.41 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| BCAR1_HUMAN_832 | 18 | 832 | 849 | AAALQYPSPSAAQDMVER | PRIDE |
| PAp00042624 | 32 | 492 | 523 | SPSEPQEPLVQDLQAAVAAVQSAVHELLEFAR | Peptide Atlas |