AutismKB 2.0

Annotation Detail for CDC42BPB


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Basic Information Top
Gene Symbol:CDC42BPB ( DKFZp686H1431,FLJ37601,FLJ44730,KIAA1124,MRCKB )
Gene Full Name: CDC42 binding protein kinase beta (DMPK-like)
Band: 14q32.32
Quick LinksEntrez ID:9578; OMIM: NA; Uniprot ID:MRCKB_HUMAN; ENSEMBL ID: ENSG00000198752; HGNC ID: 1738
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst16 / 62319256
fetus49 / 56401286
neonate1 / 3109732
infant5 / 23620211
juvenile3 / 5555653
adult189 / 193912197
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma16 / 82823193
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor19 / 119369159
germ cell tumor15 / 26384556
glioma12 / 106883112
head and neck tumor33 / 136302242
kidney tumor3 / 6895943
leukemia3 / 9584231
liver tumor6 / 9635962
lung tumor10 / 10312796
lymphoma1 / 7175513
non-neoplasia7 / 9725071
normal266 / 336030779
ovarian tumor6 / 7668278
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer10 / 10268097
retinoblastoma8 / 46356172
skin tumor9 / 12494972
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites10 / 40015249
bladder2 / 2975767
blood2 / 12347816
bone9 / 71655125
bone marrow0 / 488010 
brain70 / 110098963
cervix2 / 4817141
connective tissue13 / 14925587
ear1 / 1621261
embryonic tissue27 / 215722125
esophagus0 / 202090 
eye48 / 211054227
heart1 / 8962611
intestine14 / 23447259
kidney8 / 21177737
larynx4 / 24145165
liver11 / 20774352
lung33 / 33697497
lymph1 / 4427022
lymph node3 / 9161032
mammary gland21 / 153271137
mouth11 / 67052164
muscle10 / 10771592
nerve2 / 15768126
ovary10 / 10205197
pancreas10 / 21481246
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta22 / 28082578
prostate15 / 18934579
salivary gland11 / 20155545
skin23 / 210574109
spleen0 / 539520 
stomach14 / 96619144
testis27 / 33044281
thymus0 / 811310 
thyroid6 / 47473126
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217849_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.8
Adipocyte87.5
AdrenalCortex33.85
Adrenalgland38.2
Amygdala383.4
Appendix13
AtrioventricularNode15.7
BDCA4+_DentriticCells8.45
Bonemarrow13.15
BronchialEpithelialCells13.8
CD105+_Endothelial9.55
CD14+_Monocytes16.45
CD19+_BCells(neg._sel.)13
CD33+_Myeloid14.65
CD34+8.65
CD4+_Tcells7.45
CD56+_NKCells8.45
CD71+_EarlyErythroid10.5
CD8+_Tcells5.25
CardiacMyocytes28.55
Caudatenucleus86.2
Cerebellum50.95
CerebellumPeduncles20.5
CiliaryGanglion8.7
CingulateCortex48.9
Colorectaladenocarcinoma123
DorsalRootGanglion10.9
FetalThyroid35.7
Fetalbrain98.45
Fetalliver11.65
Fetallung50.4
GlobusPallidus15.9
Heart20.85
Hypothalamus62.35
Kidney29.25
Leukemia_chronicMyelogenousK-56216.15
Leukemia_promyelocytic-HL-609.65
Leukemialymphoblastic(MOLT-4)7.05
Liver23.55
Lung110.95
Lymphnode11.35
Lymphoma_burkitts(Daudi)14.15
Lymphoma_burkitts(Raji)17.25
MedullaOblongata47.8
OccipitalLobe89.25
OlfactoryBulb44.45
Ovary16.2
Pancreas9.85
PancreaticIslet22.05
ParietalLobe49.15
Pituitary19.85
Placenta102.7
Pons43.4
PrefrontalCortex504.2
Prostate91.9
Salivarygland12.8
SkeletalMuscle16.2
Skin18.55
SmoothMuscle67.85
Spinalcord113.7
SubthalamicNucleus25.6
SuperiorCervicalGanglion17.6
TemporalLobe23.75
Testis36.1
TestisGermCell49
TestisIntersitial17.75
TestisLeydigCell21.1
TestisSeminiferousTubule17
Thalamus84.25
Thymus8.6
Thyroid224.65
Tongue18.45
Tonsil14.15
Trachea18.05
TrigeminalGanglion12.35
Uterus68.55
UterusCorpus13.25
WholeBlood13.5
Wholebrain113.8
colon12.4
pineal_day135.2
pineal_night124.18
retina110.525
small_intestine10.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9056_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.65 ± 0.34
Basal Forebrain5.53 ± 0.27
Basal Part of Pons5.37 ± 0.27
Cerebellar Cortex5.1 ± 0.26
Cerebellar Nuclei5.24 ± 0.43
Claustrum6 ± 0.62
Epithalamus4.95 ± 0.28
Frontal Lobe5.34 ± 0.41
Globus Pallidus5.83 ± 0.39
Hypothalamus4.96 ± 0.45
Insula5.37 ± 0.42
Limbic Lobe5.8 ± 0.32
Mesencephalon5.36 ± 0.59
Myelencephalon5.47 ± 0.44
Occipital Lobe5.62 ± 0.4
Parietal Lobe5.51 ± 0.48
Pontine Tegmentum5.44 ± 0.42
Striatum5.53 ± 0.36
Subthalamus5.18 ± 0.35
Temporal Lobe5.46 ± 0.49
Thalamus5.29 ± 0.47
White Matter6.23 ± 0.16
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MRCKB_HUMAN_1697 15 1697 1711 SQLPLEGLEQPACDT PRIDE
MRCKB_HUMAN_61 13 61 73 PFTQLVKEMQLHR PRIDE
PAp00027474 8 115 122 RAETACFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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