Annotation Detail for PREPL
Basic Information Top
| Gene Symbol: | PREPL ( FLJ16627,KIAA0436 ) |
|---|---|
| Gene Full Name: | prolyl endopeptidase-like |
| Band: | 2p21 |
| Quick Links | Entrez ID:9581; OMIM: 609557; Uniprot ID:PPCEL_HUMAN; ENSEMBL ID: ENSG00000138078; HGNC ID: 30228 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.727511
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 9 / 70761 | 127 |  |
| blastocyst | 3 / 62319 | 48 |  |
| fetus | 93 / 564012 | 164 | |
| neonate | 4 / 31097 | 128 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 9 / 55556 | 161 | |
| adult | 118 / 1939121 | 60 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 7 / 82823 | 84 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 31 / 263845 | 117 | |
| glioma | 6 / 106883 | 56 | |
| head and neck tumor | 13 / 136302 | 95 | |
| kidney tumor | 9 / 68959 | 130 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 3 / 71755 | 41 | |
| non-neoplasia | 7 / 97250 | 71 | |
| normal | 1024 / 3360307 | 304 |  |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 9 / 104616 | 86 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 19 / 124949 | 152 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 3 / 13106 | 228 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 2 / 29757 | 67 | |
| blood | 2 / 123478 | 16 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 917 / 1100989 | 832 | |
| cervix | 6 / 48171 | 124 | |
| connective tissue | 10 / 149255 | 66 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 17 / 215722 | 78 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 15 / 211054 | 71 | |
| heart | 7 / 89626 | 78 | |
| intestine | 12 / 234472 | 51 | |
| kidney | 33 / 211777 | 155 | |
| larynx | 0 / 24145 | 0 | |
| liver | 9 / 207743 | 43 | |
| lung | 19 / 336974 | 56 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 11 / 67052 | 164 | |
| muscle | 10 / 107715 | 92 | |
| nerve | 7 / 15768 | 443 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 23 / 214812 | 107 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 10 / 280825 | 35 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 35 / 210574 | 166 | |
| spleen | 4 / 53952 | 74 | |
| stomach | 1 / 96619 | 10 | |
| testis | 68 / 330442 | 205 | |
| thymus | 10 / 81131 | 123 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 26 / 52413 | 496 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 22 / 232878 | 94 | |
| vascular | 4 / 51780 | 77 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 212216_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 138.45 | |
| Adipocyte | 8.75 | |
| AdrenalCortex | 6.9 | |
| Adrenalgland | 5.3 | |
| Amygdala | 65.4 | |
| Appendix | 6.6 | |
| AtrioventricularNode | 5 | |
| BDCA4+_DentriticCells | 24.75 | |
| Bonemarrow | 6.45 | |
| BronchialEpithelialCells | 7.5 | |
| CD105+_Endothelial | 8.75 | |
| CD14+_Monocytes | 10.2 | |
| CD19+_BCells(neg._sel.) | 8.3 | |
| CD33+_Myeloid | 7.5 | |
| CD34+ | 7.65 | |
| CD4+_Tcells | 20.85 | |
| CD56+_NKCells | 13.35 | |
| CD71+_EarlyErythroid | 6.1 | |
| CD8+_Tcells | 22.3 | |
| CardiacMyocytes | 8.4 | |
| Caudatenucleus | 38.15 | |
| Cerebellum | 40.05 | |
| CerebellumPeduncles | 117.2 | |
| CiliaryGanglion | 4.65 | |
| CingulateCortex | 81.7 | |
| Colorectaladenocarcinoma | 6.15 | |
| DorsalRootGanglion | 5.1 | |
| FetalThyroid | 6.9 | |
| Fetalbrain | 22.15 | |
| Fetalliver | 5.5 | |
| Fetallung | 4.7 | |
| GlobusPallidus | 44.15 | |
| Heart | 8.25 | |
| Hypothalamus | 74.3 | |
| Kidney | 5.8 | |
| Leukemia_chronicMyelogenousK-562 | 5.95 | |
| Leukemia_promyelocytic-HL-60 | 5.8 | |
| Leukemialymphoblastic(MOLT-4) | 4.6 | |
| Liver | 6.45 | |
| Lung | 6.3 | |
| Lymphnode | 5.25 | |
| Lymphoma_burkitts(Daudi) | 8.6 | |
| Lymphoma_burkitts(Raji) | 9.1 | |
| MedullaOblongata | 75.2 | |
| OccipitalLobe | 216.1 | |
| OlfactoryBulb | 5.15 | |
| Ovary | 11.1 | |
| Pancreas | 5.3 | |
| PancreaticIslet | 6.75 | |
| ParietalLobe | 76.75 | |
| Pituitary | 97.9 | |
| Placenta | 6.1 | |
| Pons | 45.35 | |
| PrefrontalCortex | 92.4 | |
| Prostate | 7.3 | |
| Salivarygland | 5.95 | |
| SkeletalMuscle | 7.9 | |
| Skin | 3.9 | |
| SmoothMuscle | 43.65 | |
| Spinalcord | 7 | |
| SubthalamicNucleus | 114.65 | |
| SuperiorCervicalGanglion | 7.9 | |
| TemporalLobe | 67.65 | |
| Testis | 5.5 | |
| TestisGermCell | 12.65 | |
| TestisIntersitial | 5.85 | |
| TestisLeydigCell | 8.1 | |
| TestisSeminiferousTubule | 5.55 | |
| Thalamus | 39.3 | |
| Thymus | 4.55 | |
| Thyroid | 8.15 | |
| Tongue | 6.5 | |
| Tonsil | 5.95 | |
| Trachea | 5.4 | |
| TrigeminalGanglion | 6.65 | |
| Uterus | 5.75 | |
| UterusCorpus | 5.8 | |
| WholeBlood | 6.8 | |
| Wholebrain | 40.15 | |
| colon | 8.5 | |
| pineal_day | 320.58 | |
| pineal_night | 356.42 | |
| retina | 25.25 | |
| small_intestine | 6.05 | |
- Probe name: A_23_P165325
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 11.86 ± 0.26 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 11.56 ± 0.16 | |
| Basal Part of Pons | 12.14 ± 0.2 | |
| Cerebellar Cortex | 11.67 ± 0.14 | |
| Cerebellar Nuclei | 11.28 ± 0.32 | |
| Claustrum | 11.63 ± 0.19 | |
| Epithalamus | 11.13 ± 0.46 | |
| Frontal Lobe | 11.8 ± 0.34 | |
| Globus Pallidus | 10.73 ± 0.37 | |
| Hypothalamus | 11.76 ± 0.31 | |
| Insula | 11.67 ± 0.25 | |
| Limbic Lobe | 11.99 ± 0.29 | |
| Mesencephalon | 11.7 ± 0.41 | |
| Myelencephalon | 11.73 ± 0.36 | |
| Occipital Lobe | 11.99 ± 0.24 | |
| Parietal Lobe | 11.91 ± 0.31 | |
| Pontine Tegmentum | 11.66 ± 0.31 | |
| Striatum | 11.79 ± 0.26 | |
| Subthalamus | 11.65 ± 0.25 | |
| Temporal Lobe | 11.78 ± 0.24 | |
| Thalamus | 11.8 ± 0.24 | |
| White Matter | 10.89 ± 0.41 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Prepl | CB | Cerebellum | 100 | |
| 100 | | |||
| Prepl | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Prepl | HIP | Hippocampal region | 100 | |
| 100 | | |||
| Prepl | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Prepl | HY | Hypothalamus | 100 | |
| 100 | | |||
| Prepl | LSX | Lateral septal complex | 100 | |
| 100 | | |||
| Prepl | MB | Midbrain | 100 | |
| 100 | | |||
| Prepl | MY | Medulla | 100 | |
| 100 | | |||
| Prepl | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Prepl | P | Pons | 100 | |
| 100 | | |||
| Prepl | PAL | Pallidum | 100 | |
| 100 | | |||
| Prepl | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Prepl | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Prepl | STR | Striatum | 100 | |
| 100 | | |||
| Prepl | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Prepl | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Prepl | TH | Thalamus | 100 | |
| 100 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00070915 | 15 | 174 | 188 | IRTEDSEASTCVIIK | Peptide Atlas |