AutismKB 2.0

Annotation Detail for APOBEC3B


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Basic Information Top
Gene Symbol:APOBEC3B ( APOBEC1L,ARCD3,ARP4,DJ742C19.2,FLJ21201,PHRBNL,bK150C2.2 )
Gene Full Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
Band: 22q13.1
Quick LinksEntrez ID:9582; OMIM: 607110; Uniprot ID:ABC3B_HUMAN; ENSEMBL ID: ENSG00000179750; HGNC ID: 17352
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206632_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts650
Adipocyte10.55
AdrenalCortex14.7
Adrenalgland9.2
Amygdala9.45
Appendix15.25
AtrioventricularNode12.65
BDCA4+_DentriticCells61.55
Bonemarrow53.75
BronchialEpithelialCells9.65
CD105+_Endothelial483.45
CD14+_Monocytes10.6
CD19+_BCells(neg._sel.)10.1
CD33+_Myeloid12.5
CD34+12.2
CD4+_Tcells8.65
CD56+_NKCells12.55
CD71+_EarlyErythroid180.9
CD8+_Tcells8.55
CardiacMyocytes32.55
Caudatenucleus9
Cerebellum8.2
CerebellumPeduncles12.85
CiliaryGanglion10.8
CingulateCortex10.25
Colorectaladenocarcinoma816.2
DorsalRootGanglion11.4
FetalThyroid11.9
Fetalbrain9.15
Fetalliver21.45
Fetallung7.8
GlobusPallidus9
Heart18.35
Hypothalamus9.8
Kidney9.55
Leukemia_chronicMyelogenousK-56228.65
Leukemia_promyelocytic-HL-608.8
Leukemialymphoblastic(MOLT-4)6.85
Liver19.3
Lung10.95
Lymphnode7.7
Lymphoma_burkitts(Daudi)15.95
Lymphoma_burkitts(Raji)17.1
MedullaOblongata8.85
OccipitalLobe8.6
OlfactoryBulb7.25
Ovary17.6
Pancreas10.05
PancreaticIslet13.25
ParietalLobe12.1
Pituitary11.45
Placenta9.8
Pons10
PrefrontalCortex10.55
Prostate11.15
Salivarygland8.75
SkeletalMuscle21.5
Skin16.35
SmoothMuscle12.7
Spinalcord9.6
SubthalamicNucleus9.4
SuperiorCervicalGanglion31.25
TemporalLobe14.45
Testis8.25
TestisGermCell7.75
TestisIntersitial8.8
TestisLeydigCell10.8
TestisSeminiferousTubule8.5
Thalamus10.25
Thymus7.75
Thyroid11.7
Tongue13.1
Tonsil12.75
Trachea8.15
TrigeminalGanglion18.65
Uterus8.35
UterusCorpus13.25
WholeBlood10.7
Wholebrain7.35
colon68.95
pineal_day10.92
pineal_night10.8
retina11.375
small_intestine30.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P66027
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.88 ± 1.04
Basal Forebrain2.33 ± 0.27
Basal Part of Pons2.27 ± 0.68
Cerebellar Cortex2.26 ± 0.71
Cerebellar Nuclei2.81 ± 0.48
Claustrum3.28 ± 1.01
Epithalamus2.21 ± 0.78
Frontal Lobe2.55 ± 0.87
Globus Pallidus3.24 ± 0.76
Hypothalamus2.52 ± 0.79
Insula2.05 ± 0.55
Limbic Lobe2.67 ± 0.79
Mesencephalon2.71 ± 0.65
Myelencephalon2.63 ± 0.7
Occipital Lobe2.74 ± 0.71
Parietal Lobe2.46 ± 0.77
Pontine Tegmentum2.61 ± 0.79
Striatum2.75 ± 0.74
Subthalamus2.39 ± 0.76
Temporal Lobe2.5 ± 0.73
Thalamus2.56 ± 0.76
White Matter2.51 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Apobec3CBCerebellum0.62
1.05
Apobec3CTXCerebral cortex0.25
0.46
Apobec3HIPHippocampal region0.34
0.91
Apobec3HPFHippocampal formation0.53
0.98
Apobec3HYHypothalamus1.74
2.36
Apobec3LSXLateral septal complex0.36
0.41
Apobec3MBMidbrain0.53
0.9
Apobec3MYMedulla1.15
1.99
Apobec3OLFOlfactory bulb2.46
5
Apobec3PPons2
4.18
Apobec3PALPallidum0.24
0.25
Apobec3RHPRetrohippocampal region0.9
1.06
Apobec3sAMYStriatum-like amygdalar nuclei0.53
1.23
Apobec3STRStriatum0.46
0.71
Apobec3STRdStriatum dorsal region0.35
0.62
Apobec3STRvStriatum ventral region0.86
0.95
Apobec3THThalamus0.68
0.77
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00512608 16 15 30 DTFYDNFENEPILYGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018