AutismKB 2.0

Annotation Detail for ENTPD4


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Basic Information Top
Gene Symbol:ENTPD4 ( KIAA0392,LALP70,LAP70,LYSAL1,NTPDase-4,UDPase )
Gene Full Name: ectonucleoside triphosphate diphosphohydrolase 4
Band: 8p21.3
Quick LinksEntrez ID:9583; OMIM: 607577; Uniprot ID:ENTP4_HUMAN; ENSEMBL ID: ENSG00000197217; HGNC ID: 14573
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst7 / 62319112
fetus24 / 56401242
neonate0 / 310970 
infant1 / 2362042
juvenile3 / 5555653
adult85 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor19 / 26384572
glioma2 / 10688318
head and neck tumor7 / 13630251
kidney tumor2 / 6895929
leukemia27 / 95842281
liver tumor4 / 9635941
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal170 / 336030750
ovarian tumor5 / 7668265
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone8 / 71655111
bone marrow6 / 48801122
brain57 / 110098951
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue25 / 215722115
esophagus1 / 2020949
eye7 / 21105433
heart2 / 8962622
intestine8 / 23447234
kidney5 / 21177723
larynx1 / 2414541
liver10 / 20774348
lung11 / 33697432
lymph0 / 442700 
lymph node36 / 91610392
mammary gland6 / 15327139
mouth6 / 6705289
muscle10 / 10771592
nerve0 / 157680 
ovary6 / 10205158
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta17 / 28082560
prostate3 / 18934515
salivary gland0 / 201550 
skin8 / 21057437
spleen1 / 5395218
stomach2 / 9661920
testis16 / 33044248
thymus7 / 8113186
thyroid3 / 4747363
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus3 / 23287812
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204076_at
Cell line Expression level Expression bar
721_B_lymphoblasts31.1
Adipocyte6.95
AdrenalCortex8.75
Adrenalgland5.35
Amygdala92.65
Appendix9.35
AtrioventricularNode4.3
BDCA4+_DentriticCells187.35
Bonemarrow7.35
BronchialEpithelialCells18.95
CD105+_Endothelial20.15
CD14+_Monocytes36.15
CD19+_BCells(neg._sel.)94.4
CD33+_Myeloid84.75
CD34+51.2
CD4+_Tcells203.05
CD56+_NKCells101.4
CD71+_EarlyErythroid5.55
CD8+_Tcells229
CardiacMyocytes23.2
Caudatenucleus16.4
Cerebellum15.9
CerebellumPeduncles25.2
CiliaryGanglion12.9
CingulateCortex64.3
Colorectaladenocarcinoma60.95
DorsalRootGanglion8.15
FetalThyroid8.55
Fetalbrain41.35
Fetalliver4.85
Fetallung18.95
GlobusPallidus18.9
Heart7
Hypothalamus59.7
Kidney5.55
Leukemia_chronicMyelogenousK-56214.3
Leukemia_promyelocytic-HL-6064.85
Leukemialymphoblastic(MOLT-4)51.45
Liver5.75
Lung5.85
Lymphnode86.2
Lymphoma_burkitts(Daudi)49.8
Lymphoma_burkitts(Raji)21.35
MedullaOblongata55.75
OccipitalLobe43.75
OlfactoryBulb5.25
Ovary4.65
Pancreas8.15
PancreaticIslet23.4
ParietalLobe23.3
Pituitary22.3
Placenta31.65
Pons21.35
PrefrontalCortex113.65
Prostate26.6
Salivarygland28.5
SkeletalMuscle8.55
Skin13.7
SmoothMuscle27.9
Spinalcord21.2
SubthalamicNucleus50.85
SuperiorCervicalGanglion15.5
TemporalLobe26.5
Testis9.25
TestisGermCell19
TestisIntersitial8.9
TestisLeydigCell11.7
TestisSeminiferousTubule20.55
Thalamus33.85
Thymus8.35
Thyroid14.15
Tongue8.8
Tonsil33.35
Trachea13.45
TrigeminalGanglion9.75
Uterus26.8
UterusCorpus7.25
WholeBlood77.25
Wholebrain50.4
colon27.35
pineal_day107.78
pineal_night85.34
retina20.575
small_intestine17
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P216017
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.28 ± 0.54
Basal Forebrain6.31 ± 0.26
Basal Part of Pons6.69 ± 0.41
Cerebellar Cortex6.67 ± 0.23
Cerebellar Nuclei6.47 ± 0.51
Claustrum6.15 ± 0.37
Epithalamus6.05 ± 0.5
Frontal Lobe6.47 ± 0.45
Globus Pallidus5.49 ± 0.41
Hypothalamus6.17 ± 0.54
Insula6.42 ± 0.3
Limbic Lobe6.32 ± 0.47
Mesencephalon6.28 ± 0.45
Myelencephalon6.35 ± 0.49
Occipital Lobe6.6 ± 0.44
Parietal Lobe6.58 ± 0.39
Pontine Tegmentum6.39 ± 0.47
Striatum5.73 ± 0.36
Subthalamus6.28 ± 0.62
Temporal Lobe6.5 ± 0.35
Thalamus6.49 ± 0.41
White Matter6.19 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Entpd4CBCerebellum27.28
41.44
Entpd4CTXCerebral cortex39.8
33.52
Entpd4HIPHippocampal region24.75
29.15
Entpd4HPFHippocampal formation26.18
28.92
Entpd4HYHypothalamus19.98
17.57
Entpd4LSXLateral septal complex6.31
4.11
Entpd4MBMidbrain26.34
28.8
Entpd4MYMedulla36.01
53.31
Entpd4OLFOlfactory bulb36.33
31.47
Entpd4PPons29.84
42.13
Entpd4PALPallidum21.31
20.82
Entpd4RHPRetrohippocampal region28.08
28.35
Entpd4sAMYStriatum-like amygdalar nuclei13.58
10.24
Entpd4STRStriatum15.93
11.66
Entpd4STRdStriatum dorsal region13.78
9.58
Entpd4STRvStriatum ventral region27.32
20.22
Entpd4THThalamus15.76
13.95
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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