AutismKB 2.0

Annotation Detail for CD44


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Basic Information Top
Gene Symbol:CD44 ( CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MGC10468,MIC4,Pgp1 )
Gene Full Name: CD44 molecule (Indian blood group)
Band: 11p13
Quick LinksEntrez ID:960; OMIM: 107269; Uniprot ID:CD44_HUMAN; ENSEMBL ID: ENSG00000026508; HGNC ID: 1681
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body13 / 70761183
blastocyst4 / 6231964
fetus97 / 564012171
neonate23 / 31097739
infant3 / 23620127
juvenile8 / 55556143
adult655 / 1939121337
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma16 / 17475915
breast (mammary gland) tumor52 / 94178552
cervical tumor9 / 34366261
chondrosarcoma27 / 82823325
colorectal tumor38 / 114246332
esophageal tumor42 / 172902429
gastrointestinal tumor124 / 1193691038
germ cell tumor41 / 263845155
glioma182 / 1068831702
head and neck tumor104 / 136302763
kidney tumor50 / 68959725
leukemia18 / 95842187
liver tumor43 / 96359446
lung tumor45 / 103127436
lymphoma9 / 71755125
non-neoplasia73 / 97250750
normal854 / 3360307254
ovarian tumor4 / 7668252
pancreatic tumor46 / 104616439
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor40 / 124949320
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor29 / 90257321
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland4 / 33197120
ascites70 / 400151749
bladder32 / 297571075
blood37 / 123478299
bone17 / 71655237
bone marrow20 / 48801409
brain354 / 1100989321
cervix10 / 48171207
connective tissue102 / 149255683
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus42 / 202092078
eye40 / 211054189
heart10 / 89626111
intestine56 / 234472238
kidney91 / 211777429
larynx13 / 24145538
liver59 / 207743284
lung176 / 336974522
lymph0 / 442700 
lymph node42 / 91610458
mammary gland77 / 153271502
mouth80 / 670521193
muscle6 / 10771555
nerve1 / 1576863
ovary9 / 10205188
pancreas88 / 214812409
parathyroid0 / 205390 
pharynx9 / 41328217
pituitary gland0 / 165850 
placenta45 / 280825160
prostate30 / 189345158
salivary gland5 / 20155248
skin124 / 210574588
spleen12 / 53952222
stomach65 / 96619672
testis26 / 33044278
thymus28 / 81131345
thyroid12 / 47473252
tonsil2 / 16999117
trachea62 / 524131182
umbilical cord0 / 136800 
uterus192 / 232878824
vascular104 / 517802008
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210916_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts40.1
Adipocyte71.55
AdrenalCortex8.45
Adrenalgland6.85
Amygdala7.45
Appendix9.1
AtrioventricularNode6.35
BDCA4+_DentriticCells68.55
Bonemarrow17.35
BronchialEpithelialCells79.4
CD105+_Endothelial8
CD14+_Monocytes249.45
CD19+_BCells(neg._sel.)39.95
CD33+_Myeloid304.25
CD34+25.2
CD4+_Tcells228.5
CD56+_NKCells85.1
CD71+_EarlyErythroid20.7
CD8+_Tcells181.35
CardiacMyocytes52.7
Caudatenucleus6.6
Cerebellum6
CerebellumPeduncles8.9
CiliaryGanglion8.55
CingulateCortex7.45
Colorectaladenocarcinoma11
DorsalRootGanglion7.05
FetalThyroid7.55
Fetalbrain7.45
Fetalliver6.8
Fetallung28.65
GlobusPallidus5.8
Heart11.05
Hypothalamus8.15
Kidney6.55
Leukemia_chronicMyelogenousK-5628.65
Leukemia_promyelocytic-HL-606.8
Leukemialymphoblastic(MOLT-4)6.3
Liver10.5
Lung73.95
Lymphnode12.45
Lymphoma_burkitts(Daudi)10.05
Lymphoma_burkitts(Raji)10.4
MedullaOblongata6.6
OccipitalLobe6.65
OlfactoryBulb6.55
Ovary5.35
Pancreas6.45
PancreaticIslet21.6
ParietalLobe8.35
Pituitary8.85
Placenta10.35
Pons7.2
PrefrontalCortex8.65
Prostate27.6
Salivarygland8.65
SkeletalMuscle8.8
Skin10.95
SmoothMuscle126.35
Spinalcord10.2
SubthalamicNucleus6.95
SuperiorCervicalGanglion9.4
TemporalLobe6.9
Testis6.5
TestisGermCell6.6
TestisIntersitial6.4
TestisLeydigCell7.7
TestisSeminiferousTubule6.7
Thalamus7.6
Thymus35.35
Thyroid10.7
Tongue9.25
Tonsil48.15
Trachea15.25
TrigeminalGanglion8.1
Uterus57.5
UterusCorpus13.45
WholeBlood49.9
Wholebrain6.05
colon8.8
pineal_day9.16
pineal_night9.02
retina11.55
small_intestine7.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P24870
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.9 ± 0.86
Basal Forebrain5.13 ± 0.67
Basal Part of Pons4.23 ± 0.45
Cerebellar Cortex4.5 ± 0.6
Cerebellar Nuclei5.79 ± 0.83
Claustrum3.99 ± 0.85
Epithalamus6.93 ± 0.5
Frontal Lobe4.55 ± 1.12
Globus Pallidus7.42 ± 0.69
Hypothalamus5.3 ± 1.59
Insula4.22 ± 0.85
Limbic Lobe4.14 ± 1.23
Mesencephalon4.83 ± 0.96
Myelencephalon4.82 ± 0.84
Occipital Lobe4.16 ± 0.94
Parietal Lobe4.22 ± 1.14
Pontine Tegmentum4.68 ± 0.68
Striatum5.08 ± 1.29
Subthalamus4.66 ± 0.36
Temporal Lobe4.05 ± 1.18
Thalamus4.78 ± 0.81
White Matter6.55 ± 0.69
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cd44CBCerebellum4.69
6.32
Cd44CTXCerebral cortex0.18
0.22
Cd44HIPHippocampal region0.58
0.72
Cd44HPFHippocampal formation0.6
0.68
Cd44HYHypothalamus0.24
0.51
Cd44LSXLateral septal complex0.12
0.11
Cd44MBMidbrain0.26
0.33
Cd44MYMedulla0.22
0.4
Cd44OLFOlfactory bulb0.61
0.6
Cd44PPons0.21
0.19
Cd44PALPallidum0.36
0.42
Cd44RHPRetrohippocampal region0.52
0.54
Cd44sAMYStriatum-like amygdalar nuclei0.74
0.85
Cd44STRStriatum0.28
0.52
Cd44STRdStriatum dorsal region0.2
0.37
Cd44STRvStriatum ventral region0.25
0.77
Cd44THThalamus0.24
0.32
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CD44_HUMAN_29 9 29 37 FAGVFHVEK PRIDE
CD44_HUMAN_41 13 41 53 YSISRTEAADLCK PRIDE
CD44_HUMAN_68 10 68 77 ALSIGFETCR PRIDE
CD44_HUMAN_706 10 706 715 SQEMVHLVNK PRIDE
CD44_HUMAN_706 26 706 731 SQEMVHLVNKESSETPDQFMTADETR PRIDE
CD44_HUMAN_715 16 715 730 ESSETPDQFMTADETR PRIDE
CD44_HUMAN_716 16 716 731 ESSETPDQFMTADETR PRIDE
CD44_HUMAN_732 8 732 739 NLQNVDMK PRIDE
CD44_HUMAN_78 12 78 89 YGFIEGHVVIPR PRIDE
PAp00000556 10 69 78 ALSIGFETCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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