AutismKB 2.0

Annotation Detail for NCOR1


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Basic Information Top
Gene Symbol:NCOR1 ( KIAA1047,MGC104216,N-CoR,N-CoR1,TRAC1,hN-CoR )
Gene Full Name: nuclear receptor corepressor 1
Band: 17p12-p11.2
Quick LinksEntrez ID:9611; OMIM: 600849; Uniprot ID:NCOR1_HUMAN; ENSEMBL ID: ENSG00000141027; HGNC ID: 7672
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst5 / 6231980
fetus50 / 56401288
neonate2 / 3109764
infant1 / 2362042
juvenile4 / 5555671
adult228 / 1939121117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma3 / 17475171
breast (mammary gland) tumor9 / 9417895
cervical tumor5 / 34366145
chondrosarcoma5 / 8282360
colorectal tumor23 / 114246201
esophageal tumor4 / 17290231
gastrointestinal tumor12 / 119369100
germ cell tumor24 / 26384590
glioma5 / 10688346
head and neck tumor14 / 136302102
kidney tumor8 / 68959116
leukemia13 / 95842135
liver tumor11 / 96359114
lung tumor3 / 10312729
lymphoma3 / 7175541
non-neoplasia18 / 97250185
normal289 / 336030786
ovarian tumor5 / 7668265
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer10 / 10268097
retinoblastoma4 / 4635686
skin tumor6 / 12494948
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor19 / 90257210
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland5 / 33197150
ascites3 / 4001574
bladder5 / 29757168
blood13 / 123478105
bone9 / 71655125
bone marrow4 / 4880181
brain89 / 110098980
cervix5 / 48171103
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue25 / 215722115
esophagus4 / 20209197
eye20 / 21105494
heart7 / 8962678
intestine42 / 234472179
kidney24 / 211777113
larynx4 / 24145165
liver19 / 20774391
lung34 / 336974100
lymph1 / 4427022
lymph node14 / 91610152
mammary gland13 / 15327184
mouth7 / 67052104
muscle8 / 10771574
nerve0 / 157680 
ovary6 / 10205158
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta24 / 28082585
prostate21 / 189345110
salivary gland1 / 2015549
skin10 / 21057447
spleen1 / 5395218
stomach14 / 96619144
testis36 / 330442108
thymus7 / 8113186
thyroid7 / 47473147
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus30 / 232878128
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200854_at
Cell line Expression level Expression bar
721_B_lymphoblasts199
Adipocyte24.7
AdrenalCortex27.25
Adrenalgland37.7
Amygdala60.4
Appendix30.15
AtrioventricularNode26
BDCA4+_DentriticCells117.35
Bonemarrow34.2
BronchialEpithelialCells20.95
CD105+_Endothelial84.6
CD14+_Monocytes83.15
CD19+_BCells(neg._sel.)127.15
CD33+_Myeloid121.4
CD34+207.1
CD4+_Tcells132.65
CD56+_NKCells206.5
CD71+_EarlyErythroid69.4
CD8+_Tcells142.7
CardiacMyocytes34.15
Caudatenucleus53.75
Cerebellum49.85
CerebellumPeduncles77.45
CiliaryGanglion23.95
CingulateCortex41.2
Colorectaladenocarcinoma43.25
DorsalRootGanglion22.45
FetalThyroid55.15
Fetalbrain74.45
Fetalliver34.6
Fetallung51.65
GlobusPallidus37.15
Heart18.15
Hypothalamus47.65
Kidney55.7
Leukemia_chronicMyelogenousK-56230.7
Leukemia_promyelocytic-HL-6034.5
Leukemialymphoblastic(MOLT-4)56.75
Liver28.65
Lung25.55
Lymphnode49.4
Lymphoma_burkitts(Daudi)58.9
Lymphoma_burkitts(Raji)24.8
MedullaOblongata61.9
OccipitalLobe57.7
OlfactoryBulb45.8
Ovary30.5
Pancreas32.05
PancreaticIslet43
ParietalLobe48.95
Pituitary53.3
Placenta43.55
Pons32.8
PrefrontalCortex103.35
Prostate48.65
Salivarygland38.25
SkeletalMuscle42.55
Skin31.05
SmoothMuscle27.9
Spinalcord49.35
SubthalamicNucleus38.85
SuperiorCervicalGanglion29.55
TemporalLobe44.9
Testis40.85
TestisGermCell47.25
TestisIntersitial38.35
TestisLeydigCell47.95
TestisSeminiferousTubule40.75
Thalamus46.6
Thymus84
Thyroid61.45
Tongue28.8
Tonsil45.7
Trachea35.55
TrigeminalGanglion28.45
Uterus47.45
UterusCorpus50.75
WholeBlood88.6
Wholebrain44.9
colon48.5
pineal_day237.28
pineal_night206.46
retina67.025
small_intestine58.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P204214
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.86 ± 0.15
Basal Forebrain9.92 ± 0.1
Basal Part of Pons9.71 ± 0.17
Cerebellar Cortex9.96 ± 0.13
Cerebellar Nuclei9.72 ± 0.23
Claustrum9.98 ± 0.17
Epithalamus9.9 ± 0.12
Frontal Lobe9.74 ± 0.21
Globus Pallidus9.82 ± 0.13
Hypothalamus9.76 ± 0.19
Insula9.85 ± 0.18
Limbic Lobe9.8 ± 0.23
Mesencephalon9.78 ± 0.21
Myelencephalon9.78 ± 0.21
Occipital Lobe9.93 ± 0.14
Parietal Lobe9.86 ± 0.21
Pontine Tegmentum9.81 ± 0.21
Striatum9.67 ± 0.16
Subthalamus9.65 ± 0.13
Temporal Lobe9.84 ± 0.18
Thalamus9.78 ± 0.14
White Matter10.35 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ncor1CBCerebellum29.41
23.95
Ncor1CTXCerebral cortex11.76
7.61
Ncor1HIPHippocampal region56.05
48.47
Ncor1HPFHippocampal formation42.24
34
Ncor1HYHypothalamus3.12
1.79
Ncor1LSXLateral septal complex3.29
2.09
Ncor1MBMidbrain2.03
1.5
Ncor1MYMedulla3.68
2.77
Ncor1OLFOlfactory bulb47.25
27.34
Ncor1PPons4.27
3.43
Ncor1PALPallidum1.41
0.85
Ncor1RHPRetrohippocampal region20.31
14.57
Ncor1sAMYStriatum-like amygdalar nuclei2.96
1.87
Ncor1STRStriatum3.05
1.85
Ncor1STRdStriatum dorsal region1.32
0.87
Ncor1STRvStriatum ventral region8.77
4.56
Ncor1THThalamus3.99
2.56
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NCOR1_HUMAN_1350 7 1350 1356 SIHEIPR PRIDE
NCOR1_HUMAN_234 11 234 244 SIVQIIYDENR PRIDE
PAp00011342 30 1876 1905 RSVQCLYTSSAFPSGKPQPHSSVVYSEAGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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