AutismKB 2.0

Annotation Detail for NCOR2


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Basic Information Top
Gene Symbol:NCOR2 ( CTG26,FLJ25011,N-CoR2,SMAP270,SMRT,SMRTE,SMRTE-tau,TNRC14,TRAC,TRAC-1,TRAC1 )
Gene Full Name: nuclear receptor corepressor 2
Band: 12q24.31
Quick LinksEntrez ID:9612; OMIM: 600848; Uniprot ID:NCOR2_HUMAN; ENSEMBL ID: ENSG00000196498; HGNC ID: 7673
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst8 / 62319128
fetus42 / 56401274
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult206 / 1939121106
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor24 / 114246210
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor20 / 26384575
glioma21 / 106883196
head and neck tumor21 / 136302154
kidney tumor6 / 6895987
leukemia22 / 95842229
liver tumor7 / 9635972
lung tumor16 / 103127155
lymphoma7 / 7175597
non-neoplasia2 / 9725020
normal228 / 336030767
ovarian tumor16 / 76682208
pancreatic tumor19 / 104616181
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer4 / 10268038
retinoblastoma9 / 46356194
skin tumor27 / 124949216
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood9 / 12347872
bone4 / 7165555
bone marrow0 / 488010 
brain58 / 110098952
cervix2 / 4817141
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue27 / 215722125
esophagus0 / 202090 
eye27 / 211054127
heart3 / 8962633
intestine30 / 234472127
kidney13 / 21177761
larynx13 / 24145538
liver9 / 20774343
lung41 / 336974121
lymph2 / 4427045
lymph node25 / 91610272
mammary gland16 / 153271104
mouth4 / 6705259
muscle11 / 107715102
nerve2 / 15768126
ovary17 / 102051166
pancreas31 / 214812144
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta26 / 28082592
prostate13 / 18934568
salivary gland1 / 2015549
skin36 / 210574170
spleen1 / 5395218
stomach8 / 9661982
testis3 / 3304429
thymus4 / 8113149
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207760_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts648.9
Adipocyte220.65
AdrenalCortex250.95
Adrenalgland241.6
Amygdala462.3
Appendix100
AtrioventricularNode103.35
BDCA4+_DentriticCells659.9
Bonemarrow131.9
BronchialEpithelialCells178.6
CD105+_Endothelial473.55
CD14+_Monocytes634.55
CD19+_BCells(neg._sel.)335
CD33+_Myeloid976
CD34+567.35
CD4+_Tcells246.6
CD56+_NKCells429.65
CD71+_EarlyErythroid169.65
CD8+_Tcells223.2
CardiacMyocytes267.75
Caudatenucleus187.8
Cerebellum224.3
CerebellumPeduncles257.45
CiliaryGanglion124.2
CingulateCortex287.55
Colorectaladenocarcinoma240.25
DorsalRootGanglion135.45
FetalThyroid280.8
Fetalbrain216.05
Fetalliver123.45
Fetallung239.65
GlobusPallidus155.75
Heart373.5
Hypothalamus350.7
Kidney139.35
Leukemia_chronicMyelogenousK-562200.7
Leukemia_promyelocytic-HL-60161.5
Leukemialymphoblastic(MOLT-4)492.6
Liver270.65
Lung1065.55
Lymphnode184.5
Lymphoma_burkitts(Daudi)267.35
Lymphoma_burkitts(Raji)519.5
MedullaOblongata225.1
OccipitalLobe212.05
OlfactoryBulb250.65
Ovary86.65
Pancreas226.8
PancreaticIslet258.35
ParietalLobe220.55
Pituitary318.95
Placenta273.6
Pons170
PrefrontalCortex617.75
Prostate603.4
Salivarygland160.65
SkeletalMuscle177.5
Skin119.35
SmoothMuscle498
Spinalcord251.05
SubthalamicNucleus191.45
SuperiorCervicalGanglion159.45
TemporalLobe204.15
Testis186.4
TestisGermCell277.65
TestisIntersitial149.15
TestisLeydigCell142.8
TestisSeminiferousTubule120.3
Thalamus222.05
Thymus286.65
Thyroid362.6
Tongue120.15
Tonsil184.75
Trachea184.05
TrigeminalGanglion81.9
Uterus608.45
UterusCorpus147.35
WholeBlood235.45
Wholebrain320.9
colon204.95
pineal_day326.38
pineal_night374.58
retina632.4
small_intestine195.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P203891
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.22 ± 0.29
Basal Forebrain11.91 ± 0.22
Basal Part of Pons12.36 ± 0.21
Cerebellar Cortex12.11 ± 0.29
Cerebellar Nuclei12.19 ± 0.25
Claustrum11.97 ± 0.22
Epithalamus11.79 ± 0.27
Frontal Lobe12 ± 0.3
Globus Pallidus11.74 ± 0.2
Hypothalamus11.64 ± 0.2
Insula12.1 ± 0.32
Limbic Lobe12.25 ± 0.31
Mesencephalon11.89 ± 0.28
Myelencephalon12.03 ± 0.31
Occipital Lobe12.31 ± 0.22
Parietal Lobe12.21 ± 0.23
Pontine Tegmentum12 ± 0.29
Striatum11.52 ± 0.39
Subthalamus12.08 ± 0.22
Temporal Lobe12.21 ± 0.21
Thalamus11.8 ± 0.26
White Matter11.92 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ncor2CBCerebellum11.03
11.94
Ncor2CTXCerebral cortex80.9
64.42
Ncor2HIPHippocampal region71.25
100
Ncor2HPFHippocampal formation68.02
85.08
Ncor2HYHypothalamus19.09
15.19
Ncor2LSXLateral septal complex62.78
51.1
Ncor2MBMidbrain19.47
18.38
Ncor2MYMedulla27.77
31.08
Ncor2OLFOlfactory bulb57.76
53.92
Ncor2PPons26.74
29.73
Ncor2PALPallidum14.34
11.86
Ncor2RHPRetrohippocampal region64.86
56.1
Ncor2sAMYStriatum-like amygdalar nuclei15.14
10.7
Ncor2STRStriatum10.75
8.4
Ncor2STRdStriatum dorsal region6.81
5.61
Ncor2STRvStriatum ventral region6.5
4.39
Ncor2THThalamus16.5
14.44
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011510 26 2420 2445 SPAPGLASGDRPPSVSSVHSEGDCNR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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