Annotation Detail for MTRF1
Basic Information Top
| Gene Symbol: | MTRF1 ( MGC47721,MRF1,MTTRF1,RF1 ) |
|---|---|
| Gene Full Name: | mitochondrial translational release factor 1 |
| Band: | 13q14.11 |
| Quick Links | Entrez ID:9617; OMIM: 604601; Uniprot ID:RF1M_HUMAN; ENSEMBL ID: ENSG00000120662; HGNC ID: 7469 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.382176
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 21 / 564012 | 37 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 17 / 1939121 | 8 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 2 / 34366 | 58 |  |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 69 / 3360307 | 20 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 16 / 1100989 | 14 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 1 / 89626 | 11 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 1 / 24145 | 41 | |
| liver | 1 / 207743 | 4 | |
| lung | 2 / 336974 | 5 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 3 / 280825 | 10 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 4 / 330442 | 12 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 219822_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 30.85 | |
| Adipocyte | 9.7 | |
| AdrenalCortex | 12.9 | |
| Adrenalgland | 8.65 | |
| Amygdala | 9.45 | |
| Appendix | 10.75 | |
| AtrioventricularNode | 8.45 | |
| BDCA4+_DentriticCells | 26.45 | |
| Bonemarrow | 10.6 | |
| BronchialEpithelialCells | 9.25 | |
| CD105+_Endothelial | 12.5 | |
| CD14+_Monocytes | 10.45 | |
| CD19+_BCells(neg._sel.) | 22.6 | |
| CD33+_Myeloid | 12.45 | |
| CD34+ | 44.85 | |
| CD4+_Tcells | 130.7 | |
| CD56+_NKCells | 16.1 | |
| CD71+_EarlyErythroid | 9.55 | |
| CD8+_Tcells | 169.7 | |
| CardiacMyocytes | 23.75 | |
| Caudatenucleus | 8.8 | |
| Cerebellum | 7.9 | |
| CerebellumPeduncles | 11.8 | |
| CiliaryGanglion | 7.7 | |
| CingulateCortex | 10.55 | |
| Colorectaladenocarcinoma | 11.4 | |
| DorsalRootGanglion | 8.1 | |
| FetalThyroid | 9.85 | |
| Fetalbrain | 9.8 | |
| Fetalliver | 8.85 | |
| Fetallung | 6.35 | |
| GlobusPallidus | 7.65 | |
| Heart | 15.75 | |
| Hypothalamus | 10.6 | |
| Kidney | 8.55 | |
| Leukemia_chronicMyelogenousK-562 | 10.05 | |
| Leukemia_promyelocytic-HL-60 | 10.95 | |
| Leukemialymphoblastic(MOLT-4) | 8.05 | |
| Liver | 14 | |
| Lung | 10.5 | |
| Lymphnode | 10.7 | |
| Lymphoma_burkitts(Daudi) | 15.8 | |
| Lymphoma_burkitts(Raji) | 16.7 | |
| MedullaOblongata | 8.85 | |
| OccipitalLobe | 8.2 | |
| OlfactoryBulb | 7.8 | |
| Ovary | 7.25 | |
| Pancreas | 12.1 | |
| PancreaticIslet | 10.3 | |
| ParietalLobe | 11.55 | |
| Pituitary | 10.65 | |
| Placenta | 8.4 | |
| Pons | 9.7 | |
| PrefrontalCortex | 11.05 | |
| Prostate | 11.3 | |
| Salivarygland | 8.3 | |
| SkeletalMuscle | 17.2 | |
| Skin | 9.8 | |
| SmoothMuscle | 11.15 | |
| Spinalcord | 10.35 | |
| SubthalamicNucleus | 9.75 | |
| SuperiorCervicalGanglion | 12.55 | |
| TemporalLobe | 9.35 | |
| Testis | 8.1 | |
| TestisGermCell | 11.5 | |
| TestisIntersitial | 10.2 | |
| TestisLeydigCell | 13.35 | |
| TestisSeminiferousTubule | 11.4 | |
| Thalamus | 10.15 | |
| Thymus | 7.6 | |
| Thyroid | 12.2 | |
| Tongue | 13 | |
| Tonsil | 10.05 | |
| Trachea | 7.75 | |
| TrigeminalGanglion | 14.05 | |
| Uterus | 7.4 | |
| UterusCorpus | 10.9 | |
| WholeBlood | 10.9 | |
| Wholebrain | 7.8 | |
| colon | 12.5 | |
| pineal_day | 12.36 | |
| pineal_night | 13.02 | |
| retina | 11.9 | |
| small_intestine | 9.7 | |
- Probe name: A_24_P349821
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.83 ± 0.51 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.83 ± 0.23 | |
| Basal Part of Pons | 4.92 ± 0.33 | |
| Cerebellar Cortex | 4.98 ± 0.3 | |
| Cerebellar Nuclei | 4.73 ± 0.47 | |
| Claustrum | 4.45 ± 0.79 | |
| Epithalamus | 4.67 ± 0.6 | |
| Frontal Lobe | 4.58 ± 0.37 | |
| Globus Pallidus | 5.24 ± 0.45 | |
| Hypothalamus | 4.4 ± 0.45 | |
| Insula | 4.48 ± 0.33 | |
| Limbic Lobe | 4.74 ± 0.43 | |
| Mesencephalon | 4.63 ± 0.52 | |
| Myelencephalon | 4.66 ± 0.46 | |
| Occipital Lobe | 5.01 ± 0.4 | |
| Parietal Lobe | 4.72 ± 0.4 | |
| Pontine Tegmentum | 4.66 ± 0.45 | |
| Striatum | 4.79 ± 0.54 | |
| Subthalamus | 4.28 ± 0.19 | |
| Temporal Lobe | 4.59 ± 0.5 | |
| Thalamus | 4.65 ± 0.36 | |
| White Matter | 5.11 ± 0.55 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Mtrf1 | CB | Cerebellum | 7.49 | |
| 9.18 | | |||
| Mtrf1 | CTX | Cerebral cortex | 26.74 | |
| 20.02 | | |||
| Mtrf1 | HIP | Hippocampal region | 24.74 | |
| 26.08 | | |||
| Mtrf1 | HPF | Hippocampal formation | 26.42 | |
| 25.34 | | |||
| Mtrf1 | HY | Hypothalamus | 7.68 | |
| 5.68 | | |||
| Mtrf1 | LSX | Lateral septal complex | 1.65 | |
| 2.32 | | |||
| Mtrf1 | MB | Midbrain | 2.4 | |
| 3.35 | | |||
| Mtrf1 | MY | Medulla | 5.57 | |
| 7.13 | | |||
| Mtrf1 | OLF | Olfactory bulb | 35.99 | |
| 29.88 | | |||
| Mtrf1 | P | Pons | 6.14 | |
| 7.94 | | |||
| Mtrf1 | PAL | Pallidum | 3.83 | |
| 3.25 | | |||
| Mtrf1 | RHP | Retrohippocampal region | 31.36 | |
| 25.91 | | |||
| Mtrf1 | sAMY | Striatum-like amygdalar nuclei | 10.65 | |
| 7.66 | | |||
| Mtrf1 | STR | Striatum | 6.49 | |
| 4.82 | | |||
| Mtrf1 | STRd | Striatum dorsal region | 5.38 | |
| 4 | | |||
| Mtrf1 | STRv | Striatum ventral region | 11.26 | |
| 7.36 | | |||
| Mtrf1 | TH | Thalamus | 3.59 | |
| 3.01 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| RF1M_HUMAN_0 | 1 | 0 | 0 | QNRNCILHLLSK | PRIDE |