Annotation Detail for TRAF4
Basic Information Top
| Gene Symbol: | TRAF4 ( CART1,MLN62,RNF83 ) |
|---|---|
| Gene Full Name: | TNF receptor-associated factor 4 |
| Band: | 17q11.2 |
| Quick Links | Entrez ID:9618; OMIM: 602464; Uniprot ID:TRAF4_HUMAN; ENSEMBL ID: ENSG00000076604; HGNC ID: 12034 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.8375
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 11 / 70761 | 155 |  |
| blastocyst | 7 / 62319 | 112 | |
| fetus | 38 / 564012 | 67 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 |  |
| juvenile | 10 / 55556 | 179 | |
| adult | 142 / 1939121 | 73 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 5 / 17475 | 286 |  |
| breast (mammary gland) tumor | 6 / 94178 | 63 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 14 / 114246 | 122 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 15 / 119369 | 125 | |
| germ cell tumor | 16 / 263845 | 60 | |
| glioma | 9 / 106883 | 84 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 8 / 103127 | 77 | |
| lymphoma | 7 / 71755 | 97 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 171 / 3360307 | 50 | |
| ovarian tumor | 9 / 76682 | 117 | |
| pancreatic tumor | 5 / 104616 | 47 | |
| primitive neuroectodermal tumor of the CNS | 14 / 125680 | 111 | |
| prostate cancer | 16 / 102680 | 155 | |
| retinoblastoma | 4 / 46356 | 86 | |
| skin tumor | 1 / 124949 | 8 |  |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 14 / 90257 | 155 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 10 / 123478 | 80 | |
| bone | 7 / 71655 | 97 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 46 / 1100989 | 41 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 28 / 215722 | 129 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 13 / 211054 | 61 | |
| heart | 2 / 89626 | 22 | |
| intestine | 24 / 234472 | 102 | |
| kidney | 7 / 211777 | 33 | |
| larynx | 0 / 24145 | 0 | |
| liver | 10 / 207743 | 48 | |
| lung | 15 / 336974 | 44 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 7 / 91610 | 76 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 12 / 102051 | 117 | |
| pancreas | 6 / 214812 | 27 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 11 / 280825 | 39 | |
| prostate | 18 / 189345 | 95 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 4 / 210574 | 18 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 23 / 96619 | 238 | |
| testis | 6 / 330442 | 18 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 22 / 232878 | 94 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202871_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 194.95 | |
| Adipocyte | 50.6 | |
| AdrenalCortex | 57.45 | |
| Adrenalgland | 47.2 | |
| Amygdala | 39.95 | |
| Appendix | 33.6 | |
| AtrioventricularNode | 38.1 | |
| BDCA4+_DentriticCells | 941.55 | |
| Bonemarrow | 46.65 | |
| BronchialEpithelialCells | 113.65 | |
| CD105+_Endothelial | 38.25 | |
| CD14+_Monocytes | 29.9 | |
| CD19+_BCells(neg._sel.) | 68.1 | |
| CD33+_Myeloid | 54.25 | |
| CD34+ | 63.6 | |
| CD4+_Tcells | 54.25 | |
| CD56+_NKCells | 60.65 | |
| CD71+_EarlyErythroid | 38.6 | |
| CD8+_Tcells | 42.85 | |
| CardiacMyocytes | 50.8 | |
| Caudatenucleus | 45.65 | |
| Cerebellum | 38.45 | |
| CerebellumPeduncles | 57.7 | |
| CiliaryGanglion | 30.05 | |
| CingulateCortex | 51.4 | |
| Colorectaladenocarcinoma | 127.7 | |
| DorsalRootGanglion | 42.2 | |
| FetalThyroid | 49.7 | |
| Fetalbrain | 48.85 | |
| Fetalliver | 43.15 | |
| Fetallung | 48.2 | |
| GlobusPallidus | 33.6 | |
| Heart | 59.8 | |
| Hypothalamus | 49.7 | |
| Kidney | 59.3 | |
| Leukemia_chronicMyelogenousK-562 | 54.6 | |
| Leukemia_promyelocytic-HL-60 | 124.5 | |
| Leukemialymphoblastic(MOLT-4) | 50.65 | |
| Liver | 70.85 | |
| Lung | 56.7 | |
| Lymphnode | 44.2 | |
| Lymphoma_burkitts(Daudi) | 72.9 | |
| Lymphoma_burkitts(Raji) | 522.45 | |
| MedullaOblongata | 38.25 | |
| OccipitalLobe | 37.1 | |
| OlfactoryBulb | 42.45 | |
| Ovary | 33.85 | |
| Pancreas | 105.4 | |
| PancreaticIslet | 68.15 | |
| ParietalLobe | 53.7 | |
| Pituitary | 57.45 | |
| Placenta | 52.7 | |
| Pons | 44.3 | |
| PrefrontalCortex | 52.85 | |
| Prostate | 66.6 | |
| Salivarygland | 61.1 | |
| SkeletalMuscle | 59.8 | |
| Skin | 39.8 | |
| SmoothMuscle | 63.1 | |
| Spinalcord | 52.9 | |
| SubthalamicNucleus | 39.5 | |
| SuperiorCervicalGanglion | 35.4 | |
| TemporalLobe | 46.05 | |
| Testis | 53.85 | |
| TestisGermCell | 64.85 | |
| TestisIntersitial | 46.7 | |
| TestisLeydigCell | 55.7 | |
| TestisSeminiferousTubule | 79.65 | |
| Thalamus | 50.6 | |
| Thymus | 59.75 | |
| Thyroid | 74.9 | |
| Tongue | 50.65 | |
| Tonsil | 85.55 | |
| Trachea | 52.45 | |
| TrigeminalGanglion | 52 | |
| Uterus | 30.9 | |
| UterusCorpus | 34.7 | |
| WholeBlood | 29.25 | |
| Wholebrain | 40.85 | |
| colon | 51.7 | |
| pineal_day | 57.72 | |
| pineal_night | 63.06 | |
| retina | 61.075 | |
| small_intestine | 49.5 | |
- Probe name: CUST_10040_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.57 ± 0.84 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.91 ± 0.41 | |
| Basal Part of Pons | 1.91 ± 0.59 | |
| Cerebellar Cortex | 2.02 ± 0.73 | |
| Cerebellar Nuclei | 2.39 ± 0.84 | |
| Claustrum | 2.35 ± 0.84 | |
| Epithalamus | 2.14 ± 0.57 | |
| Frontal Lobe | 2.11 ± 0.7 | |
| Globus Pallidus | 2.71 ± 0.66 | |
| Hypothalamus | 1.9 ± 0.6 | |
| Insula | 1.82 ± 0.62 | |
| Limbic Lobe | 2.16 ± 0.7 | |
| Mesencephalon | 2.16 ± 0.76 | |
| Myelencephalon | 2.27 ± 0.78 | |
| Occipital Lobe | 2.47 ± 0.81 | |
| Parietal Lobe | 2.25 ± 0.68 | |
| Pontine Tegmentum | 2.16 ± 0.75 | |
| Striatum | 2.29 ± 0.73 | |
| Subthalamus | 2.34 ± 0.41 | |
| Temporal Lobe | 2.03 ± 0.77 | |
| Thalamus | 2.37 ± 0.67 | |
| White Matter | 2.65 ± 0.41 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Traf4 | CB | Cerebellum | 1.94 | |
| 2.36 | | |||
| Traf4 | CTX | Cerebral cortex | 1.15 | |
| 1.36 | | |||
| Traf4 | HIP | Hippocampal region | 0.67 | |
| 0.7 | | |||
| Traf4 | HPF | Hippocampal formation | 0.53 | |
| 0.52 | | |||
| Traf4 | HY | Hypothalamus | 0.31 | |
| 0.21 | | |||
| Traf4 | LSX | Lateral septal complex | 0.91 | |
| 0.65 | | |||
| Traf4 | MB | Midbrain | 0.97 | |
| 1.34 | | |||
| Traf4 | MY | Medulla | 0.73 | |
| 0.9 | | |||
| Traf4 | OLF | Olfactory bulb | 1.19 | |
| 1.65 | | |||
| Traf4 | P | Pons | 0.6 | |
| 0.68 | | |||
| Traf4 | PAL | Pallidum | 0.52 | |
| 0.46 | | |||
| Traf4 | RHP | Retrohippocampal region | 0.31 | |
| 0.27 | | |||
| Traf4 | sAMY | Striatum-like amygdalar nuclei | 0.47 | |
| 0.5 | | |||
| Traf4 | STR | Striatum | 0.93 | |
| 1.18 | | |||
| Traf4 | STRd | Striatum dorsal region | 1.09 | |
| 1.58 | | |||
| Traf4 | STRv | Striatum ventral region | 0.28 | |
| 0.18 | | |||
| Traf4 | TH | Thalamus | 0.7 | |
| 0.73 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00009930 | 16 | 201 | 216 | EFVFDTIQSHQYQCPR | Peptide Atlas |
| TRAF4_HUMAN_290 | 7 | 290 | 296 | QELQELR | PRIDE |