AutismKB 2.0

Annotation Detail for FEZ1


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Basic Information Top
Gene Symbol:FEZ1 ( - )
Gene Full Name: fasciculation and elongation protein zeta 1 (zygin I)
Band: 11q24.2
Quick LinksEntrez ID:9638; OMIM: 604825; Uniprot ID:FEZ1_HUMAN; ENSEMBL ID: ENSG00000149557; HGNC ID: 3659
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus53 / 56401293
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult114 / 193912158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma17 / 106883159
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia14 / 97250143
normal234 / 336030769
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow3 / 4880161
brain185 / 1100989168
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye19 / 21105490
heart6 / 8962666
intestine3 / 23447212
kidney2 / 2117779
larynx0 / 241450 
liver3 / 20774314
lung8 / 33697423
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth1 / 6705214
muscle3 / 10771527
nerve2 / 15768126
ovary3 / 10205129
pancreas2 / 2148129
parathyroid3 / 20539146
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta11 / 28082539
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach1 / 9661910
testis12 / 33044236
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus3 / 23287812
vascular3 / 5178057
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203562_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.65
Adipocyte54.95
AdrenalCortex6.1
Adrenalgland7.15
Amygdala1873.55
Appendix37.05
AtrioventricularNode18.9
BDCA4+_DentriticCells6.3
Bonemarrow5.75
BronchialEpithelialCells446.05
CD105+_Endothelial7.6
CD14+_Monocytes5.7
CD19+_BCells(neg._sel.)5.6
CD33+_Myeloid7.55
CD34+6.65
CD4+_Tcells5
CD56+_NKCells72.15
CD71+_EarlyErythroid5.45
CD8+_Tcells5.35
CardiacMyocytes74.1
Caudatenucleus1832.05
Cerebellum1056.8
CerebellumPeduncles1606.45
CiliaryGanglion67.9
CingulateCortex1211.25
Colorectaladenocarcinoma5.85
DorsalRootGanglion175.35
FetalThyroid6.55
Fetalbrain1372.35
Fetalliver26.55
Fetallung16.65
GlobusPallidus512.6
Heart118.95
Hypothalamus3753.1
Kidney4.45
Leukemia_chronicMyelogenousK-56225.25
Leukemia_promyelocytic-HL-605.15
Leukemialymphoblastic(MOLT-4)4.85
Liver27.1
Lung128
Lymphnode10.8
Lymphoma_burkitts(Daudi)7.4
Lymphoma_burkitts(Raji)8.05
MedullaOblongata1880.35
OccipitalLobe2011.9
OlfactoryBulb987.15
Ovary4
Pancreas5.5
PancreaticIslet6.25
ParietalLobe2746.05
Pituitary41.2
Placenta11
Pons906.6
PrefrontalCortex1718.25
Prostate9.4
Salivarygland4.9
SkeletalMuscle6.95
Skin4.6
SmoothMuscle438.75
Spinalcord4555.85
SubthalamicNucleus681
SuperiorCervicalGanglion19.05
TemporalLobe614.25
Testis110.8
TestisGermCell90.25
TestisIntersitial28.5
TestisLeydigCell23.25
TestisSeminiferousTubule53.05
Thalamus2404.3
Thymus5.05
Thyroid8
Tongue5.65
Tonsil6.1
Trachea7.8
TrigeminalGanglion89.25
Uterus38.45
UterusCorpus6.75
WholeBlood5.85
Wholebrain2878.2
colon8.4
pineal_day142.46
pineal_night92.08
retina2256.05
small_intestine14.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15576_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.4 ± 0.4
Basal Forebrain8.57 ± 0.17
Basal Part of Pons8.32 ± 0.33
Cerebellar Cortex8.14 ± 0.16
Cerebellar Nuclei8.91 ± 0.42
Claustrum8.71 ± 0.43
Epithalamus8.19 ± 0.4
Frontal Lobe8.45 ± 0.31
Globus Pallidus9.13 ± 0.2
Hypothalamus8.44 ± 0.52
Insula8.18 ± 0.26
Limbic Lobe8.29 ± 0.34
Mesencephalon8.57 ± 0.37
Myelencephalon8.44 ± 0.37
Occipital Lobe8.16 ± 0.31
Parietal Lobe8.44 ± 0.34
Pontine Tegmentum8.45 ± 0.34
Striatum8.52 ± 0.33
Subthalamus8.51 ± 0.05
Temporal Lobe8.37 ± 0.27
Thalamus8.45 ± 0.33
White Matter9.75 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fez1CBCerebellum100
100
Fez1CTXCerebral cortex100
100
Fez1HIPHippocampal region100
100
Fez1HPFHippocampal formation100
100
Fez1HYHypothalamus100
100
Fez1LSXLateral septal complex100
100
Fez1MBMidbrain100
100
Fez1MYMedulla100
100
Fez1OLFOlfactory bulb100
100
Fez1PPons100
100
Fez1PALPallidum100
100
Fez1RHPRetrohippocampal region100
100
Fez1sAMYStriatum-like amygdalar nuclei100
100
Fez1STRStriatum100
100
Fez1STRdStriatum dorsal region100
100
Fez1STRvStriatum ventral region100
100
Fez1THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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