AutismKB 2.0

Annotation Detail for ZNF516


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Basic Information Top
Gene Symbol:ZNF516 ( HsT287 )
Gene Full Name: zinc finger protein 516
Band: 18q23
Quick LinksEntrez ID:9658; OMIM: NA; Uniprot ID:ZN516_HUMAN; ENSEMBL ID: ENSG00000101493; HGNC ID: 28990
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus27 / 56401247
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal93 / 336030727
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma25 / 46356539
skin tumor1 / 1249498
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone1 / 7165513
bone marrow0 / 488010 
brain15 / 110098913
cervix1 / 4817120
connective tissue16 / 149255107
ear4 / 16212246
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye35 / 211054165
heart4 / 8962644
intestine4 / 23447217
kidney2 / 2117779
larynx0 / 241450 
liver3 / 20774314
lung21 / 33697462
lymph0 / 442700 
lymph node4 / 9161043
mammary gland4 / 15327126
mouth1 / 6705214
muscle1 / 1077159
nerve2 / 15768126
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach0 / 966190 
testis19 / 33044257
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203604_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.9
Adipocyte5.75
AdrenalCortex6.5
Adrenalgland5.2
Amygdala6.1
Appendix6.5
AtrioventricularNode5.1
BDCA4+_DentriticCells8.65
Bonemarrow6.1
BronchialEpithelialCells5.65
CD105+_Endothelial6
CD14+_Monocytes9.65
CD19+_BCells(neg._sel.)6.15
CD33+_Myeloid26.75
CD34+10.35
CD4+_Tcells6.2
CD56+_NKCells8.4
CD71+_EarlyErythroid5.55
CD8+_Tcells5.6
CardiacMyocytes8.65
Caudatenucleus5.25
Cerebellum4.7
CerebellumPeduncles6.8
CiliaryGanglion4.55
CingulateCortex5.9
Colorectaladenocarcinoma5.9
DorsalRootGanglion4.8
FetalThyroid5.7
Fetalbrain5.95
Fetalliver5.2
Fetallung4.55
GlobusPallidus5.7
Heart8.7
Hypothalamus6.15
Kidney5.1
Leukemia_chronicMyelogenousK-5625.15
Leukemia_promyelocytic-HL-605.2
Leukemialymphoblastic(MOLT-4)4.5
Liver7.95
Lung6.55
Lymphnode4.9
Lymphoma_burkitts(Daudi)7.65
Lymphoma_burkitts(Raji)8.75
MedullaOblongata5.25
OccipitalLobe5.15
OlfactoryBulb4.75
Ovary6
Pancreas4.6
PancreaticIslet8.3
ParietalLobe6.35
Pituitary6.85
Placenta5.85
Pons5.75
PrefrontalCortex7.25
Prostate7.6
Salivarygland4.85
SkeletalMuscle7.85
Skin4.6
SmoothMuscle6.75
Spinalcord6.25
SubthalamicNucleus5.45
SuperiorCervicalGanglion7.6
TemporalLobe5.4
Testis5.15
TestisGermCell11.05
TestisIntersitial5.45
TestisLeydigCell6.3
TestisSeminiferousTubule5.15
Thalamus5.85
Thymus4.45
Thyroid7.45
Tongue6.25
Tonsil5.8
Trachea5.15
TrigeminalGanglion6.45
Uterus65.1
UterusCorpus8.8
WholeBlood9.55
Wholebrain4.7
colon6.05
pineal_day7.22
pineal_night7.2
retina13.15
small_intestine6.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P55606
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.28 ± 0.23
Basal Forebrain5.95 ± 0.32
Basal Part of Pons5.76 ± 0.32
Cerebellar Cortex5.55 ± 0.24
Cerebellar Nuclei5.79 ± 0.39
Claustrum5.61 ± 0.64
Epithalamus6.03 ± 0.65
Frontal Lobe5.82 ± 0.38
Globus Pallidus6.63 ± 0.37
Hypothalamus5.76 ± 0.44
Insula5.87 ± 0.33
Limbic Lobe6.16 ± 0.42
Mesencephalon6.05 ± 0.39
Myelencephalon6.04 ± 0.47
Occipital Lobe6.18 ± 0.42
Parietal Lobe5.96 ± 0.44
Pontine Tegmentum5.93 ± 0.46
Striatum6.91 ± 0.41
Subthalamus5.51 ± 0.55
Temporal Lobe5.87 ± 0.33
Thalamus6.05 ± 0.41
White Matter5.23 ± 0.25
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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