AutismKB 2.0

Annotation Detail for PDE4DIP


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Basic Information Top
Gene Symbol:PDE4DIP ( CMYA2,DKFZp781J054,MGC75440,MMGL )
Gene Full Name: phosphodiesterase 4D interacting protein
Band: 1q21.2
Quick LinksEntrez ID:9659; OMIM: 608117; Uniprot ID:MYOME_HUMAN; ENSEMBL ID: ENSG00000178104; HGNC ID: 15580
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult30 / 193912115
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult35 / 193912118
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal74 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal65 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal11 / 33603073
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain27 / 110098924
cervix0 / 481710 
connective tissue5 / 14925533
ear1 / 1621261
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye12 / 21105456
heart0 / 896260 
intestine4 / 23447217
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye5 / 21105423
heart3 / 8962633
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle11 / 107715102
nerve0 / 157680 
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate2 / 18934510
salivary gland1 / 2015549
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212390_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.5
Adipocyte12.15
AdrenalCortex4.6
Adrenalgland3.8
Amygdala33.35
Appendix4.5
AtrioventricularNode3.35
BDCA4+_DentriticCells4.85
Bonemarrow4.4
BronchialEpithelialCells3.7
CD105+_Endothelial3.75
CD14+_Monocytes4.55
CD19+_BCells(neg._sel.)4.8
CD33+_Myeloid5.05
CD34+5.75
CD4+_Tcells4.9
CD56+_NKCells5.35
CD71+_EarlyErythroid4.25
CD8+_Tcells4.5
CardiacMyocytes5.15
Caudatenucleus12.4
Cerebellum9.15
CerebellumPeduncles18.75
CiliaryGanglion3.3
CingulateCortex19.65
Colorectaladenocarcinoma4.05
DorsalRootGanglion3.5
FetalThyroid6.9
Fetalbrain48.6
Fetalliver3.9
Fetallung3.75
GlobusPallidus6.4
Heart32.95
Hypothalamus33.6
Kidney3.7
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)3.6
Liver5.45
Lung6.8
Lymphnode9.15
Lymphoma_burkitts(Daudi)5.65
Lymphoma_burkitts(Raji)6.2
MedullaOblongata16.45
OccipitalLobe27.55
OlfactoryBulb5.05
Ovary3
Pancreas3.65
PancreaticIslet4.8
ParietalLobe19.2
Pituitary6.8
Placenta5.45
Pons6.1
PrefrontalCortex56
Prostate5.3
Salivarygland3.65
SkeletalMuscle258.15
Skin3.4
SmoothMuscle5.1
Spinalcord22.15
SubthalamicNucleus8.8
SuperiorCervicalGanglion5.05
TemporalLobe7.55
Testis4
TestisGermCell3.75
TestisIntersitial3.8
TestisLeydigCell4.5
TestisSeminiferousTubule3.9
Thalamus33.95
Thymus3.55
Thyroid15
Tongue222.3
Tonsil4.45
Trachea3.75
TrigeminalGanglion4.55
Uterus3.7
UterusCorpus3.95
WholeBlood4.9
Wholebrain24.5
colon4.5
pineal_day5.72
pineal_night5.8
retina10.35
small_intestine4.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2487_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.73 ± 0.29
Basal Forebrain6.21 ± 0.16
Basal Part of Pons6.57 ± 0.3
Cerebellar Cortex6.65 ± 0.24
Cerebellar Nuclei5.96 ± 0.28
Claustrum6.68 ± 0.56
Epithalamus6.26 ± 0.3
Frontal Lobe6.19 ± 0.36
Globus Pallidus6.34 ± 0.39
Hypothalamus5.78 ± 0.32
Insula6.29 ± 0.33
Limbic Lobe6.64 ± 0.39
Mesencephalon6.25 ± 0.42
Myelencephalon6.29 ± 0.36
Occipital Lobe6.63 ± 0.44
Parietal Lobe6.32 ± 0.44
Pontine Tegmentum6.3 ± 0.4
Striatum6.19 ± 0.37
Subthalamus5.77 ± 0.08
Temporal Lobe6.37 ± 0.37
Thalamus6.37 ± 0.27
White Matter6.82 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pde4dipCBCerebellum37.71
49.77
Pde4dipCTXCerebral cortex94.27
73.51
Pde4dipHIPHippocampal region77.83
100
Pde4dipHPFHippocampal formation74.18
93.25
Pde4dipHYHypothalamus19.21
13.89
Pde4dipLSXLateral septal complex25.11
17.24
Pde4dipMBMidbrain22.82
18.81
Pde4dipMYMedulla25.5
24.76
Pde4dipOLFOlfactory bulb83.12
78.98
Pde4dipPPons25.86
24.21
Pde4dipPALPallidum26.67
23.05
Pde4dipRHPRetrohippocampal region70.47
59.44
Pde4dipsAMYStriatum-like amygdalar nuclei36.31
26.37
Pde4dipSTRStriatum68.34
50.63
Pde4dipSTRdStriatum dorsal region81.75
61.95
Pde4dipSTRvStriatum ventral region54.38
37.56
Pde4dipTHThalamus47.88
38.27
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00097061 27 347 373 TPVSYPLELSDLQELWDDLCEDYLPLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018