AutismKB 2.0

Annotation Detail for CEP135


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Basic Information Top
Gene Symbol:CEP135 ( CEP4,KIAA0635 )
Gene Full Name: centrosomal protein 135kDa
Band: 4q12
Quick LinksEntrez ID:9662; OMIM: 611423; Uniprot ID:CP135_HUMAN; ENSEMBL ID: ENSG00000174799; HGNC ID: 29086
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus9 / 56401215
neonate3 / 3109796
infant1 / 2362042
juvenile0 / 555560 
adult19 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal38 / 336030711
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue1 / 1492556
ear1 / 1621261
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx1 / 2414541
liver0 / 2077430 
lung0 / 3369740 
lymph1 / 4427022
lymph node3 / 9161032
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach2 / 9661920
testis3 / 3304429
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord3 / 13680219
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206003_at
Cell line Expression level Expression bar
721_B_lymphoblasts25.6
Adipocyte7.5
AdrenalCortex8.6
Adrenalgland6.8
Amygdala8.15
Appendix9.4
AtrioventricularNode7.15
BDCA4+_DentriticCells11.45
Bonemarrow8.4
BronchialEpithelialCells7.75
CD105+_Endothelial46.55
CD14+_Monocytes9.15
CD19+_BCells(neg._sel.)24.4
CD33+_Myeloid22
CD34+29.35
CD4+_Tcells11.25
CD56+_NKCells17.55
CD71+_EarlyErythroid22.05
CD8+_Tcells9.35
CardiacMyocytes12.1
Caudatenucleus6.85
Cerebellum6.35
CerebellumPeduncles9.15
CiliaryGanglion7.85
CingulateCortex8.1
Colorectaladenocarcinoma8.9
DorsalRootGanglion6.7
FetalThyroid7.7
Fetalbrain9.55
Fetalliver7.1
Fetallung5.65
GlobusPallidus6.15
Heart12.6
Hypothalamus7.85
Kidney6.95
Leukemia_chronicMyelogenousK-5626.6
Leukemia_promyelocytic-HL-607
Leukemialymphoblastic(MOLT-4)10.05
Liver10.7
Lung8.3
Lymphnode6.9
Lymphoma_burkitts(Daudi)10.95
Lymphoma_burkitts(Raji)12.4
MedullaOblongata6.95
OccipitalLobe6.95
OlfactoryBulb6.2
Ovary5.5
Pancreas6.5
PancreaticIslet8.55
ParietalLobe8.65
Pituitary9.15
Placenta7.35
Pons7.65
PrefrontalCortex9.25
Prostate9.1
Salivarygland6.65
SkeletalMuscle17.9
Skin7.05
SmoothMuscle8.45
Spinalcord8
SubthalamicNucleus7.25
SuperiorCervicalGanglion12.8
TemporalLobe7.3
Testis6.35
TestisGermCell7.25
TestisIntersitial7.3
TestisLeydigCell8
TestisSeminiferousTubule7.7
Thalamus8.1
Thymus5.9
Thyroid10.05
Tongue8.1
Tonsil7.9
Trachea6.35
TrigeminalGanglion8.85
Uterus8.2
UterusCorpus7.9
WholeBlood8.8
Wholebrain5.8
colon7.85
pineal_day9.92
pineal_night10.32
retina9.275
small_intestine7.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9978_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.8 ± 0.53
Basal Forebrain4.68 ± 0.4
Basal Part of Pons5.04 ± 0.4
Cerebellar Cortex4.97 ± 0.39
Cerebellar Nuclei5.04 ± 0.4
Claustrum4.94 ± 0.68
Epithalamus5.46 ± 0.31
Frontal Lobe4.58 ± 0.49
Globus Pallidus5.27 ± 0.4
Hypothalamus4.55 ± 0.41
Insula4.59 ± 0.34
Limbic Lobe4.81 ± 0.55
Mesencephalon4.94 ± 0.59
Myelencephalon4.79 ± 0.51
Occipital Lobe5.28 ± 0.54
Parietal Lobe4.78 ± 0.43
Pontine Tegmentum4.64 ± 0.48
Striatum4.85 ± 0.49
Subthalamus5.17 ± 0.34
Temporal Lobe4.6 ± 0.52
Thalamus4.82 ± 0.44
White Matter5.84 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cep135CBCerebellum3.96
5.64
Cep135CTXCerebral cortex2.3
2.13
Cep135HIPHippocampal region3.08
4.07
Cep135HPFHippocampal formation2.76
3.3
Cep135HYHypothalamus0.28
0.35
Cep135LSXLateral septal complex0.78
0.74
Cep135MBMidbrain1.83
2.54
Cep135MYMedulla4.74
5.26
Cep135OLFOlfactory bulb3.91
4.02
Cep135PPons2.13
2.57
Cep135PALPallidum0.21
1.25
Cep135RHPRetrohippocampal region2.11
2.11
Cep135sAMYStriatum-like amygdalar nuclei0.36
0.49
Cep135STRStriatum1.03
1.29
Cep135STRdStriatum dorsal region1.37
1.81
Cep135STRvStriatum ventral region0.35
0.37
Cep135THThalamus1.15
1.53
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00537148 7 955 961 RLEEELR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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