AutismKB 2.0

Annotation Detail for SDC3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SDC3 ( SDCN,SYND3 )
Gene Full Name: syndecan 3
Band: 1p35.2
Quick LinksEntrez ID:9672; OMIM: 186357; Uniprot ID:SDC3_HUMAN; ENSEMBL ID: ENSG00000162512; HGNC ID: 10660
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst2 / 6231932
fetus56 / 56401299
neonate3 / 3109796
infant5 / 23620211
juvenile0 / 555560 
adult81 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor13 / 26384549
glioma17 / 106883159
head and neck tumor6 / 13630244
kidney tumor5 / 6895972
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal199 / 336030759
ovarian tumor3 / 7668239
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor46 / 124949368
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone4 / 7165555
bone marrow2 / 4880140
brain119 / 1100989108
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue19 / 21572288
esophagus1 / 2020949
eye30 / 211054142
heart4 / 8962644
intestine5 / 23447221
kidney7 / 21177733
larynx2 / 2414582
liver1 / 2077434
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth2 / 6705229
muscle15 / 107715139
nerve3 / 15768190
ovary4 / 10205139
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate6 / 18934531
salivary gland0 / 201550 
skin51 / 210574242
spleen2 / 5395237
stomach0 / 966190 
testis9 / 33044227
thymus4 / 8113149
thyroid3 / 4747363
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord4 / 13680292
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P74887
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.33 ± 0.31
Basal Forebrain6.67 ± 0.42
Basal Part of Pons5.88 ± 0.43
Cerebellar Cortex5.92 ± 0.28
Cerebellar Nuclei6.27 ± 0.6
Claustrum5.97 ± 0.43
Epithalamus6.14 ± 0.53
Frontal Lobe6.32 ± 0.47
Globus Pallidus7.67 ± 0.45
Hypothalamus6.35 ± 0.32
Insula6.43 ± 0.53
Limbic Lobe6.33 ± 0.51
Mesencephalon6.49 ± 0.6
Myelencephalon6.47 ± 0.51
Occipital Lobe6.32 ± 0.41
Parietal Lobe6.19 ± 0.42
Pontine Tegmentum6.39 ± 0.41
Striatum6.54 ± 0.49
Subthalamus6.33 ± 0.56
Temporal Lobe6.48 ± 0.4
Thalamus6.59 ± 0.57
White Matter6 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sdc3CBCerebellum50.83
95.66
Sdc3CTXCerebral cortex100
100
Sdc3HIPHippocampal region73.28
100
Sdc3HPFHippocampal formation93.66
100
Sdc3HYHypothalamus100
100
Sdc3LSXLateral septal complex100
100
Sdc3MBMidbrain82.33
84.85
Sdc3MYMedulla64.12
86.94
Sdc3OLFOlfactory bulb100
100
Sdc3PPons75.01
100
Sdc3PALPallidum82.29
86.42
Sdc3RHPRetrohippocampal region100
100
Sdc3sAMYStriatum-like amygdalar nuclei100
100
Sdc3STRStriatum70.49
60.83
Sdc3STRdStriatum dorsal region57.53
48.67
Sdc3STRvStriatum ventral region65.38
51.22
Sdc3THThalamus98.81
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018