AutismKB 2.0

Annotation Detail for TTI1


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Basic Information Top
Gene Symbol:TTI1 ( KIAA0406 )
Gene Full Name: Tel2 interacting protein 1 homolog (S. pombe)
Band: 20q11.23
Quick LinksEntrez ID:9675; OMIM: NA; Uniprot ID:TTI1_HUMAN; ENSEMBL ID: ENSG00000101407; HGNC ID: 29029
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst2 / 6231932
fetus22 / 56401239
neonate2 / 3109764
infant0 / 236200 
juvenile2 / 5555635
adult74 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor6 / 34366174
chondrosarcoma5 / 8282360
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor22 / 26384583
glioma3 / 10688328
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia5 / 9584252
liver tumor8 / 9635983
lung tumor1 / 1031279
lymphoma8 / 71755111
non-neoplasia1 / 9725010
normal116 / 336030734
ovarian tumor5 / 7668265
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites5 / 40015124
bladder1 / 2975733
blood5 / 12347840
bone5 / 7165569
bone marrow2 / 4880140
brain49 / 110098944
cervix8 / 48171166
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye3 / 21105414
heart4 / 8962644
intestine7 / 23447229
kidney5 / 21177723
larynx0 / 241450 
liver9 / 20774343
lung5 / 33697414
lymph6 / 44270135
lymph node2 / 9161021
mammary gland10 / 15327165
mouth6 / 6705289
muscle1 / 1077159
nerve0 / 157680 
ovary5 / 10205148
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta13 / 28082546
prostate3 / 18934515
salivary gland0 / 201550 
skin5 / 21057423
spleen4 / 5395274
stomach1 / 9661910
testis30 / 33044290
thymus6 / 8113173
thyroid1 / 4747321
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212898_at
Cell line Expression level Expression bar
721_B_lymphoblasts69.5
Adipocyte9.6
AdrenalCortex25.3
Adrenalgland22.25
Amygdala56.95
Appendix39.75
AtrioventricularNode6.4
BDCA4+_DentriticCells16.75
Bonemarrow33.35
BronchialEpithelialCells25.9
CD105+_Endothelial49.05
CD14+_Monocytes35.05
CD19+_BCells(neg._sel.)28.35
CD33+_Myeloid39.25
CD34+59.35
CD4+_Tcells30.45
CD56+_NKCells34.3
CD71+_EarlyErythroid36.85
CD8+_Tcells43
CardiacMyocytes19.65
Caudatenucleus18.45
Cerebellum17.4
CerebellumPeduncles32
CiliaryGanglion6.05
CingulateCortex27.05
Colorectaladenocarcinoma188.45
DorsalRootGanglion23.5
FetalThyroid27.7
Fetalbrain25.25
Fetalliver20.3
Fetallung21.5
GlobusPallidus12.95
Heart45.75
Hypothalamus20.75
Kidney12.9
Leukemia_chronicMyelogenousK-56238.2
Leukemia_promyelocytic-HL-6022.05
Leukemialymphoblastic(MOLT-4)49.95
Liver49.85
Lung45.9
Lymphnode15.4
Lymphoma_burkitts(Daudi)38.75
Lymphoma_burkitts(Raji)113.2
MedullaOblongata15.25
OccipitalLobe21.05
OlfactoryBulb14.25
Ovary17.85
Pancreas26.85
PancreaticIslet52.4
ParietalLobe30.55
Pituitary38.2
Placenta26.6
Pons23.45
PrefrontalCortex31.95
Prostate89.3
Salivarygland18.35
SkeletalMuscle22.1
Skin34.5
SmoothMuscle23
Spinalcord21
SubthalamicNucleus30.1
SuperiorCervicalGanglion58.7
TemporalLobe22.5
Testis21.85
TestisGermCell17.7
TestisIntersitial27.2
TestisLeydigCell29.75
TestisSeminiferousTubule18.15
Thalamus23.3
Thymus28.2
Thyroid107.25
Tongue9.7
Tonsil26.25
Trachea15.9
TrigeminalGanglion25.1
Uterus43.65
UterusCorpus26.25
WholeBlood29.7
Wholebrain57.8
colon29.15
pineal_day50.54
pineal_night53
retina35.575
small_intestine31
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P109001
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.53 ± 0.62
Basal Forebrain3.61 ± 0.41
Basal Part of Pons3.42 ± 0.42
Cerebellar Cortex3.65 ± 0.42
Cerebellar Nuclei3.34 ± 0.48
Claustrum3.45 ± 0.85
Epithalamus3.62 ± 0.38
Frontal Lobe3.4 ± 0.52
Globus Pallidus3.39 ± 0.45
Hypothalamus3.26 ± 0.33
Insula3.32 ± 0.66
Limbic Lobe3.34 ± 0.41
Mesencephalon3.53 ± 0.61
Myelencephalon3.42 ± 0.51
Occipital Lobe3.4 ± 0.55
Parietal Lobe3.54 ± 0.52
Pontine Tegmentum3.54 ± 0.53
Striatum3.3 ± 0.49
Subthalamus3.77 ± 0.48
Temporal Lobe3.57 ± 0.45
Thalamus3.41 ± 0.55
White Matter4.49 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2610036D13RikCBCerebellum8.43
7.84
2610036D13RikCTXCerebral cortex6.87
4.26
2610036D13RikHIPHippocampal region6.66
5.91
2610036D13RikHPFHippocampal formation6.07
4.93
2610036D13RikHYHypothalamus0.67
0.74
2610036D13RikLSXLateral septal complex4.08
4.2
2610036D13RikMBMidbrain3.09
4.16
2610036D13RikMYMedulla4.13
3.79
2610036D13RikOLFOlfactory bulb8.89
6.05
2610036D13RikPPons2.79
3.19
2610036D13RikPALPallidum1.44
1.17
2610036D13RikRHPRetrohippocampal region5.58
3.99
2610036D13RiksAMYStriatum-like amygdalar nuclei1.26
1.2
2610036D13RikSTRStriatum2.23
1.72
2610036D13RikSTRdStriatum dorsal region2.09
1.67
2610036D13RikSTRvStriatum ventral region2.97
1.73
2610036D13RikTHThalamus3.97
3.11
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00063530 19 369 387 ALADILSESLHSLATSLPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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