AutismKB 2.0

Annotation Detail for GREB1


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Basic Information Top
Gene Symbol:GREB1 ( KIAA0575 )
Gene Full Name: growth regulation by estrogen in breast cancer 1
Band: 2p25.1
Quick LinksEntrez ID:9687; OMIM: 611736; Uniprot ID:GREB1_HUMAN; ENSEMBL ID: ENSG00000196208; HGNC ID: 24885
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor12 / 94178127
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal44 / 336030713
ovarian tumor7 / 7668291
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland20 / 153271130
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary9 / 10205188
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate9 / 18934547
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205862_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.85
Adipocyte8.45
AdrenalCortex12.75
Adrenalgland8.3
Amygdala12.15
Appendix12.85
AtrioventricularNode10.9
BDCA4+_DentriticCells7.9
Bonemarrow10.45
BronchialEpithelialCells8.2
CD105+_Endothelial8.6
CD14+_Monocytes9.35
CD19+_BCells(neg._sel.)9
CD33+_Myeloid10.55
CD34+10.3
CD4+_Tcells8.9
CD56+_NKCells9.5
CD71+_EarlyErythroid8.45
CD8+_Tcells7.85
CardiacMyocytes19.2
Caudatenucleus8.05
Cerebellum7.3
CerebellumPeduncles11
CiliaryGanglion10.8
CingulateCortex9.35
Colorectaladenocarcinoma8.5
DorsalRootGanglion9.2
FetalThyroid8.85
Fetalbrain8.2
Fetalliver8.05
Fetallung6.15
GlobusPallidus7.7
Heart17.05
Hypothalamus9.35
Kidney8.55
Leukemia_chronicMyelogenousK-5627.7
Leukemia_promyelocytic-HL-607.75
Leukemialymphoblastic(MOLT-4)6.35
Liver14.8
Lung9.35
Lymphnode6.85
Lymphoma_burkitts(Daudi)11.9
Lymphoma_burkitts(Raji)14.4
MedullaOblongata7.75
OccipitalLobe7.7
OlfactoryBulb6.9
Ovary129.95
Pancreas7.85
PancreaticIslet9.5
ParietalLobe10.3
Pituitary10.35
Placenta9
Pons8.7
PrefrontalCortex10.9
Prostate610.45
Salivarygland7.45
SkeletalMuscle16.45
Skin9.6
SmoothMuscle9.85
Spinalcord9.15
SubthalamicNucleus9.6
SuperiorCervicalGanglion18.4
TemporalLobe8.25
Testis7.65
TestisGermCell7.2
TestisIntersitial8.65
TestisLeydigCell11.15
TestisSeminiferousTubule7.6
Thalamus9.4
Thymus6.3
Thyroid9.85
Tongue10.95
Tonsil8.8
Trachea7.1
TrigeminalGanglion14.45
Uterus280.75
UterusCorpus11.4
WholeBlood9.05
Wholebrain7.25
colon8.55
pineal_day10.8
pineal_night10.4
retina11.125
small_intestine8.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P329768
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.02 ± 0.55
Basal Forebrain3.67 ± 0.74
Basal Part of Pons3.54 ± 0.46
Cerebellar Cortex3.05 ± 0.49
Cerebellar Nuclei3.93 ± 0.57
Claustrum3.6 ± 0.86
Epithalamus2.74 ± 0.77
Frontal Lobe3.74 ± 0.74
Globus Pallidus3.96 ± 0.55
Hypothalamus4 ± 0.95
Insula3.67 ± 0.71
Limbic Lobe3.81 ± 0.68
Mesencephalon4.06 ± 0.62
Myelencephalon3.7 ± 0.7
Occipital Lobe4.07 ± 0.63
Parietal Lobe4.01 ± 0.61
Pontine Tegmentum3.88 ± 0.7
Striatum4.29 ± 0.61
Subthalamus3.69 ± 0.52
Temporal Lobe3.85 ± 0.65
Thalamus3.55 ± 0.64
White Matter2.42 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Greb1CBCerebellum5.53
6.9
Greb1CTXCerebral cortex2.63
2.09
Greb1HIPHippocampal region1.29
1.65
Greb1HPFHippocampal formation1.47
1.57
Greb1HYHypothalamus2.01
1.66
Greb1LSXLateral septal complex0.21
0.32
Greb1MBMidbrain1.73
1.82
Greb1MYMedulla7.05
8.25
Greb1OLFOlfactory bulb5.09
3.93
Greb1PPons4.47
4.97
Greb1PALPallidum7.4
6.89
Greb1RHPRetrohippocampal region1.7
1.41
Greb1sAMYStriatum-like amygdalar nuclei12.46
9.83
Greb1STRStriatum2.48
1.97
Greb1STRdStriatum dorsal region1.26
1.03
Greb1STRvStriatum ventral region2.97
2.07
Greb1THThalamus2.28
2.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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