AutismKB 2.0

Annotation Detail for USP6NL


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Basic Information Top
Gene Symbol:USP6NL ( KIAA0019,RNTRE,TRE2NL )
Gene Full Name: USP6 N-terminal like
Band: 10p14
Quick LinksEntrez ID:9712; OMIM: 605405; Uniprot ID:US6NL_HUMAN; ENSEMBL ID: ENSG00000148429; HGNC ID: 16858
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus21 / 56401237
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor5 / 9417853
cervical tumor3 / 3436687
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor6 / 26384522
glioma3 / 10688328
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal88 / 336030726
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites4 / 4001599
bladder3 / 29757100
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain10 / 11009899
cervix3 / 4817162
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye11 / 21105452
heart1 / 8962611
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver6 / 20774328
lung4 / 33697411
lymph0 / 442700 
lymph node14 / 91610152
mammary gland5 / 15327132
mouth4 / 6705259
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta6 / 28082521
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach1 / 9661910
testis15 / 33044245
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord2 / 13680146
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204761_at
Cell line Expression level Expression bar
721_B_lymphoblasts20.15
Adipocyte16.35
AdrenalCortex32.1
Adrenalgland15.8
Amygdala12.15
Appendix22.45
AtrioventricularNode60.7
BDCA4+_DentriticCells16.6
Bonemarrow20.2
BronchialEpithelialCells12.9
CD105+_Endothelial24.2
CD14+_Monocytes21
CD19+_BCells(neg._sel.)41.8
CD33+_Myeloid20.05
CD34+23.55
CD4+_Tcells16.45
CD56+_NKCells16.85
CD71+_EarlyErythroid21.55
CD8+_Tcells14.2
CardiacMyocytes26.05
Caudatenucleus14.8
Cerebellum13.4
CerebellumPeduncles24.65
CiliaryGanglion28.9
CingulateCortex19.9
Colorectaladenocarcinoma17.2
DorsalRootGanglion21.7
FetalThyroid22.15
Fetalbrain18.55
Fetalliver14.7
Fetallung11.2
GlobusPallidus17.9
Heart25.25
Hypothalamus16.05
Kidney18
Leukemia_chronicMyelogenousK-56215.2
Leukemia_promyelocytic-HL-6017.7
Leukemialymphoblastic(MOLT-4)13.3
Liver24.65
Lung16.1
Lymphnode16.15
Lymphoma_burkitts(Daudi)26.8
Lymphoma_burkitts(Raji)39.05
MedullaOblongata14.75
OccipitalLobe14.6
OlfactoryBulb15.05
Ovary18
Pancreas16.55
PancreaticIslet18.7
ParietalLobe21.45
Pituitary22.9
Placenta22.25
Pons18
PrefrontalCortex16.6
Prostate15.55
Salivarygland20.85
SkeletalMuscle26
Skin26.45
SmoothMuscle19.15
Spinalcord21.55
SubthalamicNucleus19.8
SuperiorCervicalGanglion24.2
TemporalLobe16.55
Testis14.8
TestisGermCell15.45
TestisIntersitial18.15
TestisLeydigCell22.15
TestisSeminiferousTubule26.6
Thalamus18.1
Thymus10.8
Thyroid15.1
Tongue23.25
Tonsil18.05
Trachea13.3
TrigeminalGanglion36.55
Uterus11.55
UterusCorpus19.3
WholeBlood15.75
Wholebrain10.6
colon16.6
pineal_day21.46
pineal_night21.16
retina18.125
small_intestine15.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P138426
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.21 ± 0.39
Basal Forebrain6.34 ± 0.3
Basal Part of Pons7.03 ± 0.29
Cerebellar Cortex6.64 ± 0.34
Cerebellar Nuclei7.25 ± 0.33
Claustrum6.24 ± 0.59
Epithalamus6.65 ± 0.28
Frontal Lobe6.59 ± 0.35
Globus Pallidus7.56 ± 0.23
Hypothalamus6.22 ± 0.27
Insula6.51 ± 0.33
Limbic Lobe6.78 ± 0.38
Mesencephalon6.71 ± 0.44
Myelencephalon6.64 ± 0.4
Occipital Lobe6.98 ± 0.56
Parietal Lobe6.71 ± 0.37
Pontine Tegmentum6.59 ± 0.38
Striatum6.47 ± 0.37
Subthalamus6.93 ± 0.12
Temporal Lobe6.53 ± 0.37
Thalamus6.88 ± 0.26
White Matter7.46 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Usp6nlCBCerebellum28.07
43.41
Usp6nlCTXCerebral cortex21.72
16.71
Usp6nlHIPHippocampal region10.6
10.61
Usp6nlHPFHippocampal formation11.01
9.87
Usp6nlHYHypothalamus8.46
6.46
Usp6nlLSXLateral septal complex16.9
12.16
Usp6nlMBMidbrain14.27
13.57
Usp6nlMYMedulla17.02
17.33
Usp6nlOLFOlfactory bulb37.92
35.24
Usp6nlPPons18.61
19.42
Usp6nlPALPallidum17.11
16.94
Usp6nlRHPRetrohippocampal region11.88
9.01
Usp6nlsAMYStriatum-like amygdalar nuclei8.33
5.98
Usp6nlSTRStriatum11.16
8.28
Usp6nlSTRdStriatum dorsal region10.94
8.58
Usp6nlSTRvStriatum ventral region12.27
7.83
Usp6nlTHThalamus17.52
16.13
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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