AutismKB 2.0

Annotation Detail for NOS1AP


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Basic Information Top
Gene Symbol:NOS1AP ( 6330408P19Rik,CAPON,MGC138500 )
Gene Full Name: nitric oxide synthase 1 (neuronal) adaptor protein
Band: 1q23.3
Quick LinksEntrez ID:9722; OMIM: 605551; Uniprot ID:CAPON_HUMAN; ENSEMBL ID: ENSG00000198929; HGNC ID: 16859
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal29 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain16 / 110098914
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215153_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.65
Adipocyte18.15
AdrenalCortex23.25
Adrenalgland21.6
Amygdala39.05
Appendix18.25
AtrioventricularNode13.95
BDCA4+_DentriticCells9
Bonemarrow19.5
BronchialEpithelialCells17.3
CD105+_Endothelial10.85
CD14+_Monocytes9.9
CD19+_BCells(neg._sel.)15.1
CD33+_Myeloid15.25
CD34+8.95
CD4+_Tcells19.1
CD56+_NKCells7.35
CD71+_EarlyErythroid17.1
CD8+_Tcells14.95
CardiacMyocytes22.9
Caudatenucleus17.05
Cerebellum35.35
CerebellumPeduncles28.05
CiliaryGanglion13.3
CingulateCortex28.7
Colorectaladenocarcinoma18.35
DorsalRootGanglion17.4
FetalThyroid17.8
Fetalbrain20.7
Fetalliver15.75
Fetallung15.35
GlobusPallidus13.35
Heart23.05
Hypothalamus21.9
Kidney17.8
Leukemia_chronicMyelogenousK-56216.6
Leukemia_promyelocytic-HL-6015.25
Leukemialymphoblastic(MOLT-4)14.75
Liver23.9
Lung20.05
Lymphnode15.9
Lymphoma_burkitts(Daudi)23.3
Lymphoma_burkitts(Raji)25.4
MedullaOblongata16.8
OccipitalLobe24.9
OlfactoryBulb14.65
Ovary12.15
Pancreas17.45
PancreaticIslet21.25
ParietalLobe25.2
Pituitary21.9
Placenta19.15
Pons17.35
PrefrontalCortex82.75
Prostate21.45
Salivarygland15.55
SkeletalMuscle22.2
Skin13.9
SmoothMuscle20.05
Spinalcord19.5
SubthalamicNucleus30.1
SuperiorCervicalGanglion20.4
TemporalLobe16.75
Testis15.75
TestisGermCell16
TestisIntersitial15.3
TestisLeydigCell18.45
TestisSeminiferousTubule15.7
Thalamus19.15
Thymus14.55
Thyroid23
Tongue17.95
Tonsil17.8
Trachea16.05
TrigeminalGanglion18.5
Uterus15.15
UterusCorpus16.6
WholeBlood19
Wholebrain25.45
colon17.75
pineal_day158.16
pineal_night218.34
retina22.45
small_intestine17.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16868_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.62 ± 0.74
Basal Forebrain2.63 ± 0.25
Basal Part of Pons2.96 ± 0.48
Cerebellar Cortex3.63 ± 0.68
Cerebellar Nuclei3.2 ± 0.4
Claustrum3.73 ± 1.02
Epithalamus2.67 ± 0.85
Frontal Lobe3.39 ± 0.76
Globus Pallidus3.1 ± 0.73
Hypothalamus2.99 ± 0.36
Insula3.46 ± 0.49
Limbic Lobe3.87 ± 0.61
Mesencephalon3.26 ± 0.71
Myelencephalon3.34 ± 0.71
Occipital Lobe3.71 ± 0.82
Parietal Lobe3.37 ± 0.72
Pontine Tegmentum3.38 ± 0.75
Striatum2.29 ± 0.58
Subthalamus3.15 ± 0.66
Temporal Lobe3.35 ± 0.75
Thalamus3.19 ± 0.69
White Matter2.64 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nos1apCBCerebellum30.27
32.29
Nos1apCTXCerebral cortex100
100
Nos1apHIPHippocampal region94.81
100
Nos1apHPFHippocampal formation94.35
100
Nos1apHYHypothalamus24.28
21.95
Nos1apLSXLateral septal complex8.16
6.99
Nos1apMBMidbrain40.75
43.89
Nos1apMYMedulla35.74
41.37
Nos1apOLFOlfactory bulb69.86
67.04
Nos1apPPons27.1
31.85
Nos1apPALPallidum40.5
40.7
Nos1apRHPRetrohippocampal region93.33
100
Nos1apsAMYStriatum-like amygdalar nuclei84.35
81.35
Nos1apSTRStriatum67.04
60.71
Nos1apSTRdStriatum dorsal region65.8
60.92
Nos1apSTRvStriatum ventral region78.74
63.28
Nos1apTHThalamus85.08
91.06
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018