AutismKB 2.0

Annotation Detail for TMEM63A


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Basic Information Top
Gene Symbol:TMEM63A ( KIAA0489,KIAA0792 )
Gene Full Name: transmembrane protein 63A
Band: 1q42.12
Quick LinksEntrez ID:9725; OMIM: NA; Uniprot ID:TM63A_HUMAN; ENSEMBL ID: ENSG00000196187; HGNC ID: 29118
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst1 / 6231916
fetus20 / 56401235
neonate2 / 3109764
infant0 / 236200 
juvenile4 / 5555671
adult147 / 193912175
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor25 / 114246218
esophageal tumor2 / 17290115
gastrointestinal tumor6 / 11936950
germ cell tumor18 / 26384568
glioma3 / 10688328
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia16 / 95842166
liver tumor2 / 9635920
lung tumor7 / 10312767
lymphoma2 / 7175527
non-neoplasia10 / 97250102
normal234 / 336030769
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer12 / 102680116
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland2 / 3319760
ascites1 / 4001524
bladder1 / 2975733
blood13 / 123478105
bone2 / 7165527
bone marrow4 / 4880181
brain96 / 110098987
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus2 / 2020998
eye4 / 21105418
heart3 / 8962633
intestine50 / 234472213
kidney19 / 21177789
larynx1 / 2414541
liver5 / 20774324
lung22 / 33697465
lymph0 / 442700 
lymph node8 / 9161087
mammary gland25 / 153271163
mouth6 / 6705289
muscle4 / 10771537
nerve2 / 15768126
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta21 / 28082574
prostate15 / 18934579
salivary gland2 / 2015599
skin5 / 21057423
spleen9 / 53952166
stomach5 / 9661951
testis12 / 33044236
thymus9 / 81131110
thyroid6 / 47473126
tonsil0 / 169990 
trachea10 / 52413190
umbilical cord0 / 136800 
uterus19 / 23287881
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202699_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.05
Adipocyte3.9
AdrenalCortex4.1
Adrenalgland3.3
Amygdala4.3
Appendix3.85
AtrioventricularNode2.9
BDCA4+_DentriticCells16.85
Bonemarrow3.85
BronchialEpithelialCells3.85
CD105+_Endothelial4.05
CD14+_Monocytes4.7
CD19+_BCells(neg._sel.)7.7
CD33+_Myeloid5.5
CD34+5.1
CD4+_Tcells74.8
CD56+_NKCells4.85
CD71+_EarlyErythroid3.7
CD8+_Tcells56.85
CardiacMyocytes5.25
Caudatenucleus3.8
Cerebellum3.15
CerebellumPeduncles4.45
CiliaryGanglion2.65
CingulateCortex4.05
Colorectaladenocarcinoma5.3
DorsalRootGanglion2.95
FetalThyroid3.8
Fetalbrain3.9
Fetalliver3.4
Fetallung3.3
GlobusPallidus2.8
Heart5
Hypothalamus7.8
Kidney3.15
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-603.6
Leukemialymphoblastic(MOLT-4)3.2
Liver8.05
Lung4.65
Lymphnode4.2
Lymphoma_burkitts(Daudi)5
Lymphoma_burkitts(Raji)5.45
MedullaOblongata3.7
OccipitalLobe3.65
OlfactoryBulb3.05
Ovary2.6
Pancreas3.2
PancreaticIslet4.2
ParietalLobe4.15
Pituitary4.6
Placenta4.15
Pons3.7
PrefrontalCortex5.7
Prostate6.35
Salivarygland3.1
SkeletalMuscle4.55
Skin2.9
SmoothMuscle4.45
Spinalcord5.35
SubthalamicNucleus3.55
SuperiorCervicalGanglion4.35
TemporalLobe3.6
Testis3.4
TestisGermCell3.15
TestisIntersitial3.25
TestisLeydigCell3.85
TestisSeminiferousTubule3.35
Thalamus4
Thymus3.15
Thyroid5
Tongue3.8
Tonsil3.8
Trachea3.3
TrigeminalGanglion3.8
Uterus3.3
UterusCorpus3.45
WholeBlood4.4
Wholebrain4.5
colon3.95
pineal_day4.92
pineal_night4.84
retina7.225
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1316_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.97 ± 0.67
Basal Forebrain4.82 ± 0.56
Basal Part of Pons4.59 ± 0.77
Cerebellar Cortex4.18 ± 0.53
Cerebellar Nuclei5.92 ± 0.59
Claustrum4.47 ± 0.55
Epithalamus4.8 ± 0.51
Frontal Lobe4.55 ± 0.83
Globus Pallidus6.17 ± 0.42
Hypothalamus3.74 ± 0.66
Insula4.06 ± 0.64
Limbic Lobe4.36 ± 0.79
Mesencephalon4.64 ± 0.71
Myelencephalon4.75 ± 0.7
Occipital Lobe4.75 ± 0.65
Parietal Lobe4.55 ± 0.77
Pontine Tegmentum4.62 ± 0.81
Striatum5.23 ± 0.56
Subthalamus5.1 ± 0.57
Temporal Lobe4.37 ± 0.63
Thalamus5.04 ± 0.5
White Matter7.45 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem63aCBCerebellum19.82
18.87
Tmem63aCTXCerebral cortex12.02
7.9
Tmem63aHIPHippocampal region11.98
9.93
Tmem63aHPFHippocampal formation14.33
11.04
Tmem63aHYHypothalamus21.09
14.51
Tmem63aLSXLateral septal complex19.58
11.89
Tmem63aMBMidbrain33.38
25.09
Tmem63aMYMedulla58.17
49.96
Tmem63aOLFOlfactory bulb28.3
20.04
Tmem63aPPons57.13
49.74
Tmem63aPALPallidum23.32
17.26
Tmem63aRHPRetrohippocampal region19.31
13.37
Tmem63asAMYStriatum-like amygdalar nuclei14.96
11.81
Tmem63aSTRStriatum20.32
14.28
Tmem63aSTRdStriatum dorsal region22.78
16.49
Tmem63aSTRvStriatum ventral region15.35
9.85
Tmem63aTHThalamus22.99
16.18
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00742836 9 229 237 TLFITGLPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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