AutismKB 2.0

Annotation Detail for USP34


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Basic Information Top
Gene Symbol:USP34 ( FLJ43910,KIAA0570,KIAA0729,MGC104459 )
Gene Full Name: ubiquitin specific peptidase 34
Band: 2p15
Quick LinksEntrez ID:9736; OMIM: NA; Uniprot ID:UBP34_HUMAN; ENSEMBL ID: ENSG00000115464; HGNC ID: 20066
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst5 / 6231980
fetus91 / 564012161
neonate2 / 3109764
infant0 / 236200 
juvenile9 / 55556161
adult247 / 1939121127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor12 / 94178127
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor7 / 11424661
esophageal tumor2 / 17290115
gastrointestinal tumor12 / 119369100
germ cell tumor35 / 263845132
glioma6 / 10688356
head and neck tumor17 / 136302124
kidney tumor4 / 6895958
leukemia10 / 95842104
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma4 / 7175555
non-neoplasia5 / 9725051
normal403 / 3360307119
ovarian tumor9 / 76682117
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer12 / 102680116
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland5 / 33197150
ascites2 / 4001549
bladder4 / 29757134
blood9 / 12347872
bone3 / 7165541
bone marrow2 / 4880140
brain107 / 110098997
cervix1 / 4817120
connective tissue8 / 14925553
ear1 / 1621261
embryonic tissue24 / 215722111
esophagus2 / 2020998
eye19 / 21105490
heart10 / 89626111
intestine12 / 23447251
kidney15 / 21177770
larynx1 / 2414541
liver17 / 20774381
lung15 / 33697444
lymph0 / 442700 
lymph node22 / 91610240
mammary gland52 / 153271339
mouth5 / 6705274
muscle12 / 107715111
nerve4 / 15768253
ovary9 / 10205188
pancreas15 / 21481269
parathyroid3 / 20539146
pharynx9 / 41328217
pituitary gland2 / 16585120
placenta25 / 28082589
prostate26 / 189345137
salivary gland0 / 201550 
skin10 / 21057447
spleen2 / 5395237
stomach12 / 96619124
testis59 / 330442178
thymus13 / 81131160
thyroid3 / 4747363
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus15 / 23287864
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212066_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts342.8
Adipocyte88.65
AdrenalCortex67.1
Adrenalgland33.6
Amygdala126.7
Appendix66.1
AtrioventricularNode14.85
BDCA4+_DentriticCells343.35
Bonemarrow18.2
BronchialEpithelialCells65.8
CD105+_Endothelial283
CD14+_Monocytes159
CD19+_BCells(neg._sel.)503.75
CD33+_Myeloid402.7
CD34+487.05
CD4+_Tcells447.05
CD56+_NKCells588.85
CD71+_EarlyErythroid91
CD8+_Tcells575
CardiacMyocytes34.05
Caudatenucleus72.25
Cerebellum15
CerebellumPeduncles39.6
CiliaryGanglion18.3
CingulateCortex90.2
Colorectaladenocarcinoma83.1
DorsalRootGanglion30.75
FetalThyroid119.65
Fetalbrain286.6
Fetalliver50.1
Fetallung172.75
GlobusPallidus25.4
Heart22.2
Hypothalamus202.5
Kidney23.25
Leukemia_chronicMyelogenousK-562120.9
Leukemia_promyelocytic-HL-60182.95
Leukemialymphoblastic(MOLT-4)109
Liver30.7
Lung27.7
Lymphnode178.05
Lymphoma_burkitts(Daudi)510.2
Lymphoma_burkitts(Raji)201.6
MedullaOblongata58.45
OccipitalLobe88.2
OlfactoryBulb95.1
Ovary61.65
Pancreas82
PancreaticIslet93.15
ParietalLobe69.75
Pituitary162.6
Placenta32.1
Pons52
PrefrontalCortex292.4
Prostate151.4
Salivarygland130.7
SkeletalMuscle48.3
Skin28.85
SmoothMuscle90.05
Spinalcord102.35
SubthalamicNucleus84.1
SuperiorCervicalGanglion32.9
TemporalLobe25
Testis54.5
TestisGermCell247.8
TestisIntersitial161
TestisLeydigCell144.1
TestisSeminiferousTubule168.35
Thalamus88.7
Thymus67.2
Thyroid187.75
Tongue41.8
Tonsil178.55
Trachea42.9
TrigeminalGanglion36.65
Uterus179.75
UterusCorpus45.5
WholeBlood156.3
Wholebrain27.15
colon104.6
pineal_day275.58
pineal_night270.74
retina127.6
small_intestine58.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P28676
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.71 ± 0.3
Basal Forebrain6.88 ± 0.19
Basal Part of Pons6.41 ± 0.28
Cerebellar Cortex7.01 ± 0.17
Cerebellar Nuclei6.47 ± 0.35
Claustrum6.71 ± 0.48
Epithalamus6.81 ± 0.29
Frontal Lobe6.7 ± 0.33
Globus Pallidus6.86 ± 0.36
Hypothalamus6.98 ± 0.18
Insula6.67 ± 0.29
Limbic Lobe6.53 ± 0.36
Mesencephalon6.73 ± 0.41
Myelencephalon6.64 ± 0.42
Occipital Lobe6.54 ± 0.42
Parietal Lobe6.68 ± 0.35
Pontine Tegmentum6.68 ± 0.37
Striatum6.24 ± 0.31
Subthalamus6.71 ± 0.14
Temporal Lobe6.65 ± 0.31
Thalamus6.69 ± 0.38
White Matter7.49 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Usp34CBCerebellum12.49
15.19
Usp34CTXCerebral cortex19.89
14.92
Usp34HIPHippocampal region22.1
25.04
Usp34HPFHippocampal formation19.3
19.44
Usp34HYHypothalamus7.46
5.7
Usp34LSXLateral septal complex3.13
2.39
Usp34MBMidbrain7.95
7.7
Usp34MYMedulla10.32
9.95
Usp34OLFOlfactory bulb19.2
14.06
Usp34PPons6.16
6
Usp34PALPallidum4.94
4.04
Usp34RHPRetrohippocampal region14.79
11.67
Usp34sAMYStriatum-like amygdalar nuclei3.88
2.57
Usp34STRStriatum2.73
1.97
Usp34STRdStriatum dorsal region1.92
1.5
Usp34STRvStriatum ventral region4.5
2.82
Usp34THThalamus7.52
6.36
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00025456 17 3509 3525 GLFSHMQQHDILDTLCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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