AutismKB 2.0

Annotation Detail for IFT140


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Basic Information Top
Gene Symbol:IFT140 ( DKFZp564L232,FLJ10306,FLJ30571,KIAA0590,WDTC2,c305C8.4,c380F5.1,gs114 )
Gene Full Name: intraflagellar transport 140 homolog (Chlamydomonas)
Band: 16p13.3
Quick LinksEntrez ID:9742; OMIM: NA; Uniprot ID:IF140_HUMAN; ENSEMBL ID: ENSG00000187535; HGNC ID: 29077
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst6 / 6231996
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult52 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor7 / 26384526
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor5 / 10312748
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal65 / 336030719
ovarian tumor10 / 76682130
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood5 / 12347840
bone0 / 716550 
bone marrow0 / 488010 
brain21 / 110098919
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye8 / 21105437
heart2 / 8962622
intestine5 / 23447221
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung10 / 33697429
lymph1 / 4427022
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary11 / 102051107
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach3 / 9661931
testis23 / 33044269
thymus3 / 8113136
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204792_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.75
Adipocyte6.9
AdrenalCortex9.15
Adrenalgland6.3
Amygdala7.35
Appendix8.25
AtrioventricularNode7.65
BDCA4+_DentriticCells7.3
Bonemarrow7.3
BronchialEpithelialCells6.85
CD105+_Endothelial7
CD14+_Monocytes7.55
CD19+_BCells(neg._sel.)7.25
CD33+_Myeloid8.65
CD34+8.8
CD4+_Tcells7.3
CD56+_NKCells9.5
CD71+_EarlyErythroid6.75
CD8+_Tcells6.8
CardiacMyocytes13.75
Caudatenucleus6.45
Cerebellum6.05
CerebellumPeduncles8.75
CiliaryGanglion5.5
CingulateCortex7.75
Colorectaladenocarcinoma7.25
DorsalRootGanglion6.55
FetalThyroid12
Fetalbrain7.95
Fetalliver6.35
Fetallung6.05
GlobusPallidus5.9
Heart11.8
Hypothalamus11.45
Kidney6.55
Leukemia_chronicMyelogenousK-5626.4
Leukemia_promyelocytic-HL-606.3
Leukemialymphoblastic(MOLT-4)5.5
Liver11.05
Lung11.05
Lymphnode5.8
Lymphoma_burkitts(Daudi)9.5
Lymphoma_burkitts(Raji)11.25
MedullaOblongata6.45
OccipitalLobe6.4
OlfactoryBulb5.8
Ovary5.45
Pancreas5.9
PancreaticIslet7.8
ParietalLobe8.25
Pituitary8.6
Placenta7.1
Pons7.2
PrefrontalCortex10.15
Prostate9.15
Salivarygland6.1
SkeletalMuscle10.9
Skin7.1
SmoothMuscle8.15
Spinalcord8.15
SubthalamicNucleus6.85
SuperiorCervicalGanglion14.55
TemporalLobe6.85
Testis7.4
TestisGermCell5.75
TestisIntersitial7.55
TestisLeydigCell7.45
TestisSeminiferousTubule6.35
Thalamus7.6
Thymus5.4
Thyroid55.55
Tongue8.65
Tonsil7
Trachea5.95
TrigeminalGanglion7.85
Uterus8.9
UterusCorpus7.5
WholeBlood7.7
Wholebrain6.1
colon7.2
pineal_day8.96
pineal_night8.82
retina10.975
small_intestine6.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8626_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.29 ± 0.54
Basal Forebrain4.22 ± 0.47
Basal Part of Pons4.27 ± 0.71
Cerebellar Cortex4.17 ± 0.52
Cerebellar Nuclei4.04 ± 0.43
Claustrum4.42 ± 0.84
Epithalamus4.2 ± 0.59
Frontal Lobe4.31 ± 0.58
Globus Pallidus4.66 ± 0.56
Hypothalamus4.06 ± 0.43
Insula4.16 ± 0.5
Limbic Lobe4.53 ± 0.74
Mesencephalon4.29 ± 0.51
Myelencephalon4.39 ± 0.6
Occipital Lobe4.37 ± 0.69
Parietal Lobe4.22 ± 0.51
Pontine Tegmentum4.19 ± 0.59
Striatum4.33 ± 0.67
Subthalamus4.01 ± 0.43
Temporal Lobe4.33 ± 0.53
Thalamus4.25 ± 0.57
White Matter4.49 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ift140CBCerebellum2.34
2.24
Ift140CTXCerebral cortex2.25
1.6
Ift140HIPHippocampal region3.78
3.29
Ift140HPFHippocampal formation3.48
2.78
Ift140HYHypothalamus1.53
1.4
Ift140LSXLateral septal complex0.06
0.06
Ift140MBMidbrain0.66
0.67
Ift140MYMedulla2.79
3.41
Ift140OLFOlfactory bulb8.19
6.93
Ift140PPons1.33
1.5
Ift140PALPallidum1.4
1.05
Ift140RHPRetrohippocampal region3.07
2.15
Ift140sAMYStriatum-like amygdalar nuclei0.79
0.71
Ift140STRStriatum0.62
0.5
Ift140STRdStriatum dorsal region0.31
0.23
Ift140STRvStriatum ventral region1.71
1.29
Ift140THThalamus1.29
1.02
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
IF140_HUMAN_1142 9 1142 1150 AVELLLAAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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