AutismKB 2.0

Annotation Detail for ARHGAP32


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Basic Information Top
Gene Symbol:ARHGAP32 ( GC-GAP,GRIT,KIAA0712,MGC1892,PX-RICS,RICS,p200RhoGAP,p250GAP )
Gene Full Name: Rho GTPase activating protein 32
Band: 11q24.3
Quick LinksEntrez ID:9743; OMIM: 608541; Uniprot ID:RHG32_HUMAN; ENSEMBL ID: ENSG00000134909; HGNC ID: 17399
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus36 / 56401263
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult122 / 193912162
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor9 / 9417895
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor22 / 114246192
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor14 / 26384553
glioma5 / 10688346
head and neck tumor18 / 136302132
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal187 / 336030755
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer5 / 10268048
retinoblastoma8 / 46356172
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder3 / 29757100
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain83 / 110098975
cervix0 / 481710 
connective tissue3 / 14925520
ear3 / 16212185
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye21 / 21105499
heart2 / 8962622
intestine34 / 234472145
kidney7 / 21177733
larynx1 / 2414541
liver4 / 20774319
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland15 / 15327197
mouth10 / 67052149
muscle8 / 10771574
nerve4 / 15768253
ovary2 / 10205119
pancreas11 / 21481251
parathyroid2 / 2053997
pharynx8 / 41328193
pituitary gland0 / 165850 
placenta10 / 28082535
prostate6 / 18934531
salivary gland0 / 201550 
skin7 / 21057433
spleen3 / 5395255
stomach14 / 96619144
testis17 / 33044251
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203431_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.8
Adipocyte4.3
AdrenalCortex4.55
Adrenalgland3.6
Amygdala16.9
Appendix4.8
AtrioventricularNode3.35
BDCA4+_DentriticCells4.7
Bonemarrow4.15
BronchialEpithelialCells4.35
CD105+_Endothelial4.35
CD14+_Monocytes4.45
CD19+_BCells(neg._sel.)4.65
CD33+_Myeloid5.5
CD34+5.7
CD4+_Tcells4.65
CD56+_NKCells4.6
CD71+_EarlyErythroid4.1
CD8+_Tcells3.95
CardiacMyocytes5.4
Caudatenucleus4.15
Cerebellum3.5
CerebellumPeduncles4.9
CiliaryGanglion3.1
CingulateCortex86.9
Colorectaladenocarcinoma4.6
DorsalRootGanglion3.25
FetalThyroid4.2
Fetalbrain4.4
Fetalliver3.7
Fetallung3.5
GlobusPallidus54.3
Heart5.4
Hypothalamus5
Kidney3.45
Leukemia_chronicMyelogenousK-5623.85
Leukemia_promyelocytic-HL-603.7
Leukemialymphoblastic(MOLT-4)3.45
Liver5.65
Lung4.7
Lymphnode3.65
Lymphoma_burkitts(Daudi)5.4
Lymphoma_burkitts(Raji)6
MedullaOblongata65.7
OccipitalLobe157.6
OlfactoryBulb4.8
Ovary2.9
Pancreas15.75
PancreaticIslet4.6
ParietalLobe102.5
Pituitary5.1
Placenta4.7
Pons27.8
PrefrontalCortex40.3
Prostate5.1
Salivarygland3.4
SkeletalMuscle5.05
Skin3.8
SmoothMuscle4.9
Spinalcord4.6
SubthalamicNucleus54.55
SuperiorCervicalGanglion5
TemporalLobe41.85
Testis4.6
TestisGermCell3.7
TestisIntersitial3.7
TestisLeydigCell4.25
TestisSeminiferousTubule3.7
Thalamus4.4
Thymus4.4
Thyroid5.35
Tongue5.05
Tonsil4.4
Trachea5.1
TrigeminalGanglion6.1
Uterus3.55
UterusCorpus3.85
WholeBlood4.5
Wholebrain22.2
colon12.7
pineal_day6.96
pineal_night5.78
retina6
small_intestine7.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P161686
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.73 ± 0.52
Basal Forebrain7.38 ± 0.29
Basal Part of Pons7.43 ± 0.47
Cerebellar Cortex6.98 ± 0.24
Cerebellar Nuclei7.22 ± 0.62
Claustrum7.43 ± 0.6
Epithalamus7.38 ± 0.63
Frontal Lobe7.69 ± 0.5
Globus Pallidus6.51 ± 0.8
Hypothalamus7.31 ± 0.4
Insula7.73 ± 0.37
Limbic Lobe7.45 ± 0.65
Mesencephalon7.26 ± 0.61
Myelencephalon7.42 ± 0.51
Occipital Lobe7.39 ± 0.63
Parietal Lobe7.69 ± 0.55
Pontine Tegmentum7.56 ± 0.55
Striatum7.48 ± 0.78
Subthalamus7.42 ± 0.45
Temporal Lobe7.84 ± 0.43
Thalamus7.33 ± 0.36
White Matter5.98 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
GritCBCerebellum46.26
100
GritCTXCerebral cortex100
100
GritHIPHippocampal region94.17
100
GritHPFHippocampal formation100
100
GritHYHypothalamus73.84
69.66
GritLSXLateral septal complex100
100
GritMBMidbrain85.8
90.44
GritMYMedulla78.78
100
GritOLFOlfactory bulb100
100
GritPPons73.89
92.5
GritPALPallidum69.62
74.83
GritRHPRetrohippocampal region100
100
GritsAMYStriatum-like amygdalar nuclei92.3
97.49
GritSTRStriatum100
100
GritSTRdStriatum dorsal region100
100
GritSTRvStriatum ventral region100
100
GritTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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