AutismKB 2.0

Annotation Detail for FAM65B


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Basic Information Top
Gene Symbol:FAM65B ( C6orf32,DIFF40,DIFF48,KIAA0386,PL48 )
Gene Full Name: family with sequence similarity 65, member B
Band: 6p22.3-p21.32
Quick LinksEntrez ID:9750; OMIM: 611410; Uniprot ID:FA65B_HUMAN; ENSEMBL ID: ENSG00000111913; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult83 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor13 / 26384549
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia17 / 95842177
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal257 / 336030776
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood81 / 123478655
bone0 / 716550 
bone marrow9 / 48801184
brain34 / 110098930
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine4 / 23447217
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung3 / 3369748
lymph0 / 442700 
lymph node29 / 91610316
mammary gland2 / 15327113
mouth0 / 670520 
muscle8 / 10771574
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx8 / 41328193
pituitary gland2 / 16585120
placenta28 / 28082599
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen28 / 53952518
stomach1 / 9661910
testis14 / 33044242
thymus11 / 81131135
thyroid1 / 4747321
tonsil1 / 1699958
trachea2 / 5241338
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209829_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.55
Adipocyte6.8
AdrenalCortex7.85
Adrenalgland6.2
Amygdala83.55
Appendix8.3
AtrioventricularNode6.75
BDCA4+_DentriticCells121
Bonemarrow10.5
BronchialEpithelialCells6.35
CD105+_Endothelial7.8
CD14+_Monocytes134.5
CD19+_BCells(neg._sel.)499.75
CD33+_Myeloid188.35
CD34+17.85
CD4+_Tcells549.6
CD56+_NKCells282.15
CD71+_EarlyErythroid6.6
CD8+_Tcells605.45
CardiacMyocytes10.45
Caudatenucleus6.75
Cerebellum5.45
CerebellumPeduncles8.4
CiliaryGanglion5.9
CingulateCortex7.3
Colorectaladenocarcinoma6.65
DorsalRootGanglion6.15
FetalThyroid6.9
Fetalbrain21.9
Fetalliver6
Fetallung6.3
GlobusPallidus5.5
Heart9.85
Hypothalamus10.1
Kidney5.95
Leukemia_chronicMyelogenousK-5626.1
Leukemia_promyelocytic-HL-6029
Leukemialymphoblastic(MOLT-4)5.65
Liver9.8
Lung7.35
Lymphnode105.85
Lymphoma_burkitts(Daudi)16.2
Lymphoma_burkitts(Raji)45.1
MedullaOblongata6.4
OccipitalLobe10.25
OlfactoryBulb5.3
Ovary4.95
Pancreas5.75
PancreaticIslet7.15
ParietalLobe7.65
Pituitary13.15
Placenta13.05
Pons6.95
PrefrontalCortex15.9
Prostate7.9
Salivarygland6.55
SkeletalMuscle9.4
Skin6.2
SmoothMuscle7.85
Spinalcord7.25
SubthalamicNucleus6.65
SuperiorCervicalGanglion13.1
TemporalLobe6.65
Testis5.75
TestisGermCell5.4
TestisIntersitial5.85
TestisLeydigCell7.05
TestisSeminiferousTubule6.05
Thalamus7.2
Thymus9.9
Thyroid8.1
Tongue7.4
Tonsil31.7
Trachea6.1
TrigeminalGanglion8.65
Uterus69.3
UterusCorpus6.75
WholeBlood1175.75
Wholebrain8
colon6.7
pineal_day8.28
pineal_night8.1
retina8.625
small_intestine6.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6675_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.71 ± 0.46
Basal Forebrain5.24 ± 0.49
Basal Part of Pons4.14 ± 0.78
Cerebellar Cortex3.35 ± 0.57
Cerebellar Nuclei3.75 ± 0.34
Claustrum4.37 ± 0.68
Epithalamus4.26 ± 0.7
Frontal Lobe4.13 ± 0.72
Globus Pallidus3.42 ± 1.28
Hypothalamus3.94 ± 0.63
Insula4.56 ± 0.31
Limbic Lobe4.66 ± 0.71
Mesencephalon4.07 ± 0.73
Myelencephalon4.14 ± 0.74
Occipital Lobe3.29 ± 0.94
Parietal Lobe3.96 ± 0.65
Pontine Tegmentum4.05 ± 0.91
Striatum5.03 ± 0.42
Subthalamus3.49 ± 0.84
Temporal Lobe4.37 ± 0.74
Thalamus3.34 ± 0.77
White Matter2.16 ± 0.69
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
6330500D04RikCBCerebellum12.59
15.81
6330500D04RikCTXCerebral cortex12.81
10.41
6330500D04RikHIPHippocampal region17.74
20.22
6330500D04RikHPFHippocampal formation21.12
22.67
6330500D04RikHYHypothalamus1.39
1.11
6330500D04RikLSXLateral septal complex78.76
78
6330500D04RikMBMidbrain2.79
2.9
6330500D04RikMYMedulla3.06
3.33
6330500D04RikOLFOlfactory bulb22.14
18.81
6330500D04RikPPons1.26
1.41
6330500D04RikPALPallidum7.16
6.6
6330500D04RikRHPRetrohippocampal region26.31
25.57
6330500D04RiksAMYStriatum-like amygdalar nuclei13.96
10.59
6330500D04RikSTRStriatum19
15.97
6330500D04RikSTRdStriatum dorsal region11.62
9.94
6330500D04RikSTRvStriatum ventral region25.82
18.07
6330500D04RikTHThalamus6
5.3
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00039726 17 35 51 CNSFIENSSALKKPQAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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