AutismKB 2.0

Annotation Detail for ZFYVE16


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Basic Information Top
Gene Symbol:ZFYVE16 ( DKFZp686E13162,ENDOFIN,KIAA0305 )
Gene Full Name: zinc finger, FYVE domain containing 16
Band: 5q14.1
Quick LinksEntrez ID:9765; OMIM: 608880; Uniprot ID:ZFY16_HUMAN; ENSEMBL ID: ENSG00000039319; HGNC ID: 20756
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus12 / 56401221
neonate0 / 310970 
infant5 / 23620211
juvenile0 / 555560 
adult82 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor8 / 9417884
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor5 / 26384518
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal139 / 336030741
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder3 / 29757100
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain50 / 110098945
cervix1 / 4817120
connective tissue0 / 1492550 
ear2 / 16212123
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye5 / 21105423
heart2 / 8962622
intestine0 / 2344720 
kidney5 / 21177723
larynx0 / 241450 
liver2 / 2077439
lung8 / 33697423
lymph1 / 4427022
lymph node4 / 9161043
mammary gland14 / 15327191
mouth0 / 670520 
muscle9 / 10771583
nerve1 / 1576863
ovary1 / 1020519
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta9 / 28082532
prostate8 / 18934542
salivary gland0 / 201550 
skin5 / 21057423
spleen2 / 5395237
stomach2 / 9661920
testis10 / 33044230
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203651_at
Cell line Expression level Expression bar
721_B_lymphoblasts24.4
Adipocyte27.95
AdrenalCortex37.5
Adrenalgland18.7
Amygdala64.6
Appendix32.25
AtrioventricularNode14.9
BDCA4+_DentriticCells31.75
Bonemarrow22.05
BronchialEpithelialCells23.35
CD105+_Endothelial31.65
CD14+_Monocytes81.1
CD19+_BCells(neg._sel.)29.4
CD33+_Myeloid70.85
CD34+38.25
CD4+_Tcells29.25
CD56+_NKCells34.15
CD71+_EarlyErythroid10.8
CD8+_Tcells29
CardiacMyocytes42.5
Caudatenucleus53.1
Cerebellum20.75
CerebellumPeduncles35.35
CiliaryGanglion24
CingulateCortex40.05
Colorectaladenocarcinoma30.5
DorsalRootGanglion23.35
FetalThyroid30.6
Fetalbrain78.8
Fetalliver27.7
Fetallung59
GlobusPallidus27.9
Heart19.3
Hypothalamus190.05
Kidney20.25
Leukemia_chronicMyelogenousK-56221.45
Leukemia_promyelocytic-HL-6013.1
Leukemialymphoblastic(MOLT-4)19.25
Liver25.6
Lung23.95
Lymphnode36.2
Lymphoma_burkitts(Daudi)31.7
Lymphoma_burkitts(Raji)40.1
MedullaOblongata56.8
OccipitalLobe77.5
OlfactoryBulb22.7
Ovary23.45
Pancreas24.7
PancreaticIslet28.2
ParietalLobe52.7
Pituitary57.35
Placenta17.3
Pons35.35
PrefrontalCortex81.15
Prostate41.6
Salivarygland24.25
SkeletalMuscle43.85
Skin27.75
SmoothMuscle31.75
Spinalcord154.85
SubthalamicNucleus27.95
SuperiorCervicalGanglion36.2
TemporalLobe27.95
Testis19
TestisGermCell65.3
TestisIntersitial18.1
TestisLeydigCell30.2
TestisSeminiferousTubule29.8
Thalamus84.25
Thymus16.65
Thyroid51.85
Tongue33.85
Tonsil26.05
Trachea19.5
TrigeminalGanglion38.7
Uterus129
UterusCorpus34.35
WholeBlood44.7
Wholebrain23.25
colon30.95
pineal_day68.74
pineal_night71.92
retina77.1
small_intestine26.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P7543
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.4 ± 0.48
Basal Forebrain7.14 ± 0.43
Basal Part of Pons6.9 ± 0.45
Cerebellar Cortex6.51 ± 0.35
Cerebellar Nuclei7.5 ± 0.54
Claustrum6.63 ± 0.54
Epithalamus7.18 ± 0.45
Frontal Lobe6.67 ± 0.56
Globus Pallidus8.08 ± 0.38
Hypothalamus6.72 ± 0.26
Insula6.44 ± 0.26
Limbic Lobe6.43 ± 0.52
Mesencephalon6.89 ± 0.59
Myelencephalon6.82 ± 0.54
Occipital Lobe6.94 ± 0.49
Parietal Lobe6.71 ± 0.54
Pontine Tegmentum6.9 ± 0.47
Striatum7.33 ± 0.57
Subthalamus7.08 ± 0.52
Temporal Lobe6.61 ± 0.41
Thalamus7.18 ± 0.42
White Matter9.18 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfyve16CBCerebellum2.1
1.66
Zfyve16CTXCerebral cortex9.7
3.42
Zfyve16HIPHippocampal region7.61
4.73
Zfyve16HPFHippocampal formation6.85
3.43
Zfyve16HYHypothalamus2.91
0.9
Zfyve16LSXLateral septal complex0.52
0.44
Zfyve16MBMidbrain6.64
3.02
Zfyve16MYMedulla16.37
7.3
Zfyve16OLFOlfactory bulb7.48
3.6
Zfyve16PPons10.54
4.34
Zfyve16PALPallidum4.57
1.53
Zfyve16RHPRetrohippocampal region5.73
1.72
Zfyve16sAMYStriatum-like amygdalar nuclei1.49
0.62
Zfyve16STRStriatum1.3
0.65
Zfyve16STRdStriatum dorsal region1.06
0.65
Zfyve16STRvStriatum ventral region2.1
0.73
Zfyve16THThalamus2.08
0.91
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00496900 31 156 186 SNADSLIGLDLSSVSDTPCVSSTDHDSDTVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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