AutismKB 2.0

Annotation Detail for PHF16


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Basic Information Top
Gene Symbol:PHF16 ( JADE3,KIAA0215,MGC138748,MGC138749 )
Gene Full Name: PHD finger protein 16
Band: Xp11.23
Quick LinksEntrez ID:9767; OMIM: 300618; Uniprot ID:JADE3_HUMAN; ENSEMBL ID: ENSG00000102221; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor11 / 26384541
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal49 / 336030714
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood1 / 1234788
bone1 / 7165513
bone marrow1 / 4880120
brain10 / 11009899
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine1 / 2344724
kidney4 / 21177718
larynx0 / 241450 
liver3 / 20774314
lung0 / 3369740 
lymph1 / 4427022
lymph node1 / 9161010
mammary gland3 / 15327119
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach1 / 9661910
testis14 / 33044242
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204866_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.8
Adipocyte6.9
AdrenalCortex10.45
Adrenalgland17.35
Amygdala7.25
Appendix11.15
AtrioventricularNode7.2
BDCA4+_DentriticCells7.55
Bonemarrow7.4
BronchialEpithelialCells6.6
CD105+_Endothelial6.75
CD14+_Monocytes7.35
CD19+_BCells(neg._sel.)7.4
CD33+_Myeloid8.45
CD34+10.65
CD4+_Tcells6.85
CD56+_NKCells7.7
CD71+_EarlyErythroid6.65
CD8+_Tcells4.95
CardiacMyocytes11.8
Caudatenucleus6.45
Cerebellum5.7
CerebellumPeduncles8.5
CiliaryGanglion6.35
CingulateCortex7.3
Colorectaladenocarcinoma11.85
DorsalRootGanglion8.55
FetalThyroid7.65
Fetalbrain7.05
Fetalliver6.35
Fetallung6.3
GlobusPallidus6.2
Heart10.75
Hypothalamus7.2
Kidney6.35
Leukemia_chronicMyelogenousK-5626.25
Leukemia_promyelocytic-HL-606.25
Leukemialymphoblastic(MOLT-4)7.8
Liver10.5
Lung7.7
Lymphnode5.85
Lymphoma_burkitts(Daudi)9.15
Lymphoma_burkitts(Raji)11.85
MedullaOblongata6.05
OccipitalLobe6.15
OlfactoryBulb5.45
Ovary5.95
Pancreas5.85
PancreaticIslet7.35
ParietalLobe8.3
Pituitary7.95
Placenta24.85
Pons7.15
PrefrontalCortex8.4
Prostate8
Salivarygland6.1
SkeletalMuscle10.5
Skin8.15
SmoothMuscle7.95
Spinalcord7.45
SubthalamicNucleus6.8
SuperiorCervicalGanglion16.85
TemporalLobe6.75
Testis7.15
TestisGermCell9.7
TestisIntersitial6.75
TestisLeydigCell24.1
TestisSeminiferousTubule6.1
Thalamus7.4
Thymus5.55
Thyroid8.35
Tongue9.2
Tonsil7.2
Trachea5.85
TrigeminalGanglion10.55
Uterus6.55
UterusCorpus18.15
WholeBlood7.2
Wholebrain5.65
colon7.9
pineal_day8.58
pineal_night7.78
retina8.35
small_intestine6.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P11362
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.85 ± 1
Basal Forebrain1.42 ± 0.22
Basal Part of Pons1.17 ± 0.48
Cerebellar Cortex1.48 ± 0.67
Cerebellar Nuclei1.79 ± 0.69
Claustrum2.35 ± 0.8
Epithalamus1.47 ± 0.78
Frontal Lobe1.4 ± 0.64
Globus Pallidus2.03 ± 0.52
Hypothalamus1.53 ± 0.66
Insula1.43 ± 0.47
Limbic Lobe1.49 ± 0.59
Mesencephalon1.76 ± 0.73
Myelencephalon1.62 ± 0.62
Occipital Lobe1.68 ± 0.74
Parietal Lobe1.57 ± 0.7
Pontine Tegmentum1.62 ± 0.64
Striatum1.73 ± 0.59
Subthalamus1.66 ± 0.71
Temporal Lobe1.42 ± 0.62
Thalamus1.55 ± 0.58
White Matter3.69 ± 0.82
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Phf16CBCerebellum2.04
3.46
Phf16CTXCerebral cortex1.38
1.5
Phf16HIPHippocampal region1.25
1.19
Phf16HPFHippocampal formation0.93
0.84
Phf16HYHypothalamus0.06
0.13
Phf16LSXLateral septal complex0.12
0.08
Phf16MBMidbrain0.35
0.53
Phf16MYMedulla0.49
0.7
Phf16OLFOlfactory bulb0.56
0.51
Phf16PPons0.18
0.16
Phf16PALPallidum0.06
0.13
Phf16RHPRetrohippocampal region0.41
0.39
Phf16sAMYStriatum-like amygdalar nuclei0.08
0.04
Phf16STRStriatum0.15
0.14
Phf16STRdStriatum dorsal region0.2
0.17
Phf16STRvStriatum ventral region0.08
0.13
Phf16THThalamus0.73
0.63
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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