AutismKB 2.0

Annotation Detail for TM9SF4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TM9SF4 ( KIAA0255,dJ836N17.2 )
Gene Full Name: transmembrane 9 superfamily protein member 4
Band: 20q11.21
Quick LinksEntrez ID:9777; OMIM: NA; Uniprot ID:TM9S4_HUMAN; ENSEMBL ID: ENSG00000101337; HGNC ID: 30797
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst5 / 6231980
fetus51 / 56401290
neonate4 / 31097128
infant0 / 236200 
juvenile3 / 5555653
adult188 / 193912196
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor13 / 94178138
cervical tumor1 / 3436629
chondrosarcoma10 / 82823120
colorectal tumor23 / 114246201
esophageal tumor6 / 17290347
gastrointestinal tumor14 / 119369117
germ cell tumor30 / 263845113
glioma32 / 106883299
head and neck tumor38 / 136302278
kidney tumor5 / 6895972
leukemia5 / 9584252
liver tumor3 / 9635931
lung tumor8 / 10312777
lymphoma4 / 7175555
non-neoplasia10 / 97250102
normal355 / 3360307105
ovarian tumor22 / 76682286
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS20 / 125680159
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor5 / 12494940
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites2 / 4001549
bladder2 / 2975767
blood2 / 12347816
bone6 / 7165583
bone marrow3 / 4880161
brain216 / 1100989196
cervix4 / 4817183
connective tissue20 / 149255133
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus6 / 20209296
eye13 / 21105461
heart6 / 8962666
intestine48 / 234472204
kidney15 / 21177770
larynx0 / 241450 
liver11 / 20774352
lung21 / 33697462
lymph1 / 4427022
lymph node13 / 91610141
mammary gland20 / 153271130
mouth37 / 67052551
muscle13 / 107715120
nerve3 / 15768190
ovary21 / 102051205
pancreas20 / 21481293
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta35 / 280825124
prostate7 / 18934536
salivary gland0 / 201550 
skin15 / 21057471
spleen2 / 5395237
stomach6 / 9661962
testis45 / 330442136
thymus10 / 81131123
thyroid2 / 4747342
tonsil0 / 169990 
trachea16 / 52413305
umbilical cord1 / 1368073
uterus26 / 232878111
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212198_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts118.45
Adipocyte88.75
AdrenalCortex97.25
Adrenalgland93.8
Amygdala95.25
Appendix92.95
AtrioventricularNode67.1
BDCA4+_DentriticCells107.6
Bonemarrow92.6
BronchialEpithelialCells87.5
CD105+_Endothelial27.55
CD14+_Monocytes202.1
CD19+_BCells(neg._sel.)48.25
CD33+_Myeloid130.55
CD34+49.8
CD4+_Tcells93.45
CD56+_NKCells62.6
CD71+_EarlyErythroid79.85
CD8+_Tcells87.65
CardiacMyocytes112.55
Caudatenucleus111.6
Cerebellum110.05
CerebellumPeduncles165.65
CiliaryGanglion42.25
CingulateCortex114.45
Colorectaladenocarcinoma89.05
DorsalRootGanglion77.45
FetalThyroid120.85
Fetalbrain123.75
Fetalliver69.3
Fetallung74.7
GlobusPallidus75.75
Heart107.25
Hypothalamus103.6
Kidney109.05
Leukemia_chronicMyelogenousK-56282.95
Leukemia_promyelocytic-HL-6079
Leukemialymphoblastic(MOLT-4)104.2
Liver120.05
Lung70.55
Lymphnode75.55
Lymphoma_burkitts(Daudi)180.45
Lymphoma_burkitts(Raji)126.5
MedullaOblongata83.2
OccipitalLobe89.85
OlfactoryBulb87.75
Ovary63.35
Pancreas61.65
PancreaticIslet107.55
ParietalLobe119.8
Pituitary110
Placenta152.4
Pons90.4
PrefrontalCortex148.55
Prostate88.5
Salivarygland71.95
SkeletalMuscle132.2
Skin62.15
SmoothMuscle113.5
Spinalcord96.3
SubthalamicNucleus83.05
SuperiorCervicalGanglion122.6
TemporalLobe93.15
Testis73.8
TestisGermCell77.15
TestisIntersitial64.65
TestisLeydigCell90.7
TestisSeminiferousTubule79
Thalamus124.45
Thymus63.75
Thyroid86
Tongue86.25
Tonsil86.65
Trachea75.35
TrigeminalGanglion118.15
Uterus58.8
UterusCorpus79.8
WholeBlood111.4
Wholebrain75.15
colon72.8
pineal_day120.22
pineal_night111.2
retina112.2
small_intestine86.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P210872
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.91 ± 0.53
Basal Forebrain7.27 ± 0.31
Basal Part of Pons7.19 ± 0.33
Cerebellar Cortex7.14 ± 0.3
Cerebellar Nuclei7.22 ± 0.41
Claustrum7.17 ± 0.65
Epithalamus7.2 ± 0.58
Frontal Lobe7.04 ± 0.32
Globus Pallidus7.19 ± 0.37
Hypothalamus7.08 ± 0.28
Insula7.09 ± 0.28
Limbic Lobe7.04 ± 0.36
Mesencephalon7.13 ± 0.36
Myelencephalon7.06 ± 0.36
Occipital Lobe7.11 ± 0.31
Parietal Lobe7.08 ± 0.35
Pontine Tegmentum7.08 ± 0.42
Striatum7.02 ± 0.41
Subthalamus7.21 ± 0.25
Temporal Lobe7.14 ± 0.33
Thalamus7.07 ± 0.31
White Matter7.16 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tm9sf4CBCerebellum63.54
97.56
Tm9sf4CTXCerebral cortex46.93
32.58
Tm9sf4HIPHippocampal region29.94
36.26
Tm9sf4HPFHippocampal formation30.84
31.45
Tm9sf4HYHypothalamus36.81
30.16
Tm9sf4LSXLateral septal complex46.19
33.84
Tm9sf4MBMidbrain41.12
36.43
Tm9sf4MYMedulla44.64
43.64
Tm9sf4OLFOlfactory bulb45.66
39.67
Tm9sf4PPons44.79
44.98
Tm9sf4PALPallidum31.19
25.45
Tm9sf4RHPRetrohippocampal region32.3
25.05
Tm9sf4sAMYStriatum-like amygdalar nuclei36.89
26.48
Tm9sf4STRStriatum30
21.2
Tm9sf4STRdStriatum dorsal region26.02
18.12
Tm9sf4STRvStriatum ventral region35.74
24.92
Tm9sf4THThalamus43.27
33.51
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001636 21 308 328 DIANYNKEDDIEDTMEESGWK Peptide Atlas
TM9S4_HUMAN_22 13 22 34 PVEIKAVKLTSSR PRIDE
TM9S4_HUMAN_68 14 68 81 IVNTPFQVLMNSEK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved