Annotation Detail for TBC1D5
Basic Information Top
| Gene Symbol: | TBC1D5 ( KIAA0210 ) |
|---|---|
| Gene Full Name: | TBC1 domain family, member 5 |
| Band: | 3p24.3 |
| Quick Links | Entrez ID:9779; OMIM: NA; Uniprot ID:TBCD5_HUMAN; ENSEMBL ID: ENSG00000131374; HGNC ID: 19166 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.475629
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 8 / 70761 | 113 |  |
| blastocyst | 3 / 62319 | 48 |  |
| fetus | 56 / 564012 | 99 | |
| neonate | 4 / 31097 | 128 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 5 / 55556 | 89 | |
| adult | 139 / 1939121 | 71 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 12 / 82823 | 144 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 11 / 119369 | 92 | |
| germ cell tumor | 37 / 263845 | 140 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 10 / 136302 | 73 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 7 / 95842 | 73 | |
| liver tumor | 5 / 96359 | 51 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 14 / 97250 | 143 | |
| normal | 263 / 3360307 | 78 | |
| ovarian tumor | 7 / 76682 | 91 | |
| pancreatic tumor | 10 / 104616 | 95 | |
| primitive neuroectodermal tumor of the CNS | 10 / 125680 | 79 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 8 / 124949 | 64 | |
| soft tissue/muscle tissue tumor | 6 / 125191 | 47 | |
| uterine tumor | 7 / 90257 | 77 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 1 / 29757 | 33 | |
| blood | 8 / 123478 | 64 | |
| bone | 7 / 71655 | 97 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 78 / 1100989 | 70 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 16 / 149255 | 107 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 14 / 215722 | 64 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 8 / 211054 | 37 | |
| heart | 9 / 89626 | 100 | |
| intestine | 8 / 234472 | 34 | |
| kidney | 14 / 211777 | 66 | |
| larynx | 3 / 24145 | 124 | |
| liver | 9 / 207743 | 43 | |
| lung | 28 / 336974 | 83 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 17 / 91610 | 185 | |
| mammary gland | 10 / 153271 | 65 | |
| mouth | 8 / 67052 | 119 | |
| muscle | 9 / 107715 | 83 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 7 / 102051 | 68 | |
| pancreas | 19 / 214812 | 88 | |
| parathyroid | 5 / 20539 | 243 |  |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 12 / 280825 | 42 | |
| prostate | 7 / 189345 | 36 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 21 / 210574 | 99 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 11 / 96619 | 113 | |
| testis | 38 / 330442 | 114 | |
| thymus | 9 / 81131 | 110 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 3 / 16999 | 176 | |
| trachea | 8 / 52413 | 152 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 16 / 232878 | 68 | |
| vascular | 4 / 51780 | 77 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 201814_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 182 | |
| Adipocyte | 72.05 | |
| AdrenalCortex | 48.85 | |
| Adrenalgland | 59.2 | |
| Amygdala | 125.8 | |
| Appendix | 33.5 | |
| AtrioventricularNode | 37.5 | |
| BDCA4+_DentriticCells | 177.15 | |
| Bonemarrow | 55.7 | |
| BronchialEpithelialCells | 53.8 | |
| CD105+_Endothelial | 278.05 | |
| CD14+_Monocytes | 152.6 | |
| CD19+_BCells(neg._sel.) | 332.15 | |
| CD33+_Myeloid | 314.7 | |
| CD34+ | 273.95 | |
| CD4+_Tcells | 70.6 | |
| CD56+_NKCells | 246.1 | |
| CD71+_EarlyErythroid | 85.85 | |
| CD8+_Tcells | 62.1 | |
| CardiacMyocytes | 55.6 | |
| Caudatenucleus | 52.7 | |
| Cerebellum | 43.8 | |
| CerebellumPeduncles | 48.4 | |
| CiliaryGanglion | 26.45 | |
| CingulateCortex | 82.7 | |
| Colorectaladenocarcinoma | 54.45 | |
| DorsalRootGanglion | 40.75 | |
| FetalThyroid | 60.05 | |
| Fetalbrain | 57.55 | |
| Fetalliver | 48.95 | |
| Fetallung | 47.7 | |
| GlobusPallidus | 33.75 | |
| Heart | 48.85 | |
| Hypothalamus | 109.95 | |
| Kidney | 61.85 | |
| Leukemia_chronicMyelogenousK-562 | 42.9 | |
| Leukemia_promyelocytic-HL-60 | 51.5 | |
| Leukemialymphoblastic(MOLT-4) | 87.4 | |
| Liver | 52.15 | |
| Lung | 59.2 | |
| Lymphnode | 47.6 | |
| Lymphoma_burkitts(Daudi) | 85.95 | |
| Lymphoma_burkitts(Raji) | 64.2 | |
| MedullaOblongata | 49.95 | |
| OccipitalLobe | 63.3 | |
| OlfactoryBulb | 46.65 | |
| Ovary | 24 | |
| Pancreas | 27.15 | |
| PancreaticIslet | 47.9 | |
| ParietalLobe | 56.95 | |
| Pituitary | 54.2 | |
| Placenta | 53.85 | |
| Pons | 43.3 | |
| PrefrontalCortex | 150.35 | |
| Prostate | 66.35 | |
| Salivarygland | 37.5 | |
| SkeletalMuscle | 42.2 | |
| Skin | 25.25 | |
| SmoothMuscle | 55.1 | |
| Spinalcord | 133.45 | |
| SubthalamicNucleus | 37 | |
| SuperiorCervicalGanglion | 43.25 | |
| TemporalLobe | 45.6 | |
| Testis | 43.3 | |
| TestisGermCell | 46.1 | |
| TestisIntersitial | 35.85 | |
| TestisLeydigCell | 41.25 | |
| TestisSeminiferousTubule | 35 | |
| Thalamus | 65.15 | |
| Thymus | 36.75 | |
| Thyroid | 99.6 | |
| Tongue | 35.9 | |
| Tonsil | 51.55 | |
| Trachea | 39.95 | |
| TrigeminalGanglion | 31.7 | |
| Uterus | 45.55 | |
| UterusCorpus | 35.6 | |
| WholeBlood | 95.3 | |
| Wholebrain | 79.2 | |
| colon | 55.05 | |
| pineal_day | 69.42 | |
| pineal_night | 90.66 | |
| retina | 84.775 | |
| small_intestine | 56.8 | |
- Probe name: A_23_P355455
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.82 ± 0.66 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.14 ± 0.47 | |
| Basal Part of Pons | 5.18 ± 0.34 | |
| Cerebellar Cortex | 4.7 ± 0.41 | |
| Cerebellar Nuclei | 5.17 ± 0.4 | |
| Claustrum | 4.89 ± 0.68 | |
| Epithalamus | 5.18 ± 0.46 | |
| Frontal Lobe | 5 ± 0.5 | |
| Globus Pallidus | 5.36 ± 0.53 | |
| Hypothalamus | 4.5 ± 0.49 | |
| Insula | 4.87 ± 0.49 | |
| Limbic Lobe | 5.13 ± 0.6 | |
| Mesencephalon | 4.95 ± 0.47 | |
| Myelencephalon | 5.01 ± 0.5 | |
| Occipital Lobe | 5.19 ± 0.45 | |
| Parietal Lobe | 4.94 ± 0.51 | |
| Pontine Tegmentum | 5.03 ± 0.61 | |
| Striatum | 4.91 ± 0.57 | |
| Subthalamus | 5.05 ± 0.37 | |
| Temporal Lobe | 5.03 ± 0.39 | |
| Thalamus | 5.03 ± 0.45 | |
| White Matter | 6.06 ± 0.37 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Tbc1d5 | CB | Cerebellum | 8.01 | |
| 9.41 | | |||
| Tbc1d5 | CTX | Cerebral cortex | 8.42 | |
| 6.35 | | |||
| Tbc1d5 | HIP | Hippocampal region | 6.55 | |
| 6.74 | | |||
| Tbc1d5 | HPF | Hippocampal formation | 5.88 | |
| 5.39 | | |||
| Tbc1d5 | HY | Hypothalamus | 0.57 | |
| 0.45 | | |||
| Tbc1d5 | LSX | Lateral septal complex | 1.3 | |
| 0.91 | | |||
| Tbc1d5 | MB | Midbrain | 2.91 | |
| 3.04 | | |||
| Tbc1d5 | MY | Medulla | 8.03 | |
| 8.3 | | |||
| Tbc1d5 | OLF | Olfactory bulb | 7.72 | |
| 6.18 | | |||
| Tbc1d5 | P | Pons | 4.32 | |
| 4.77 | | |||
| Tbc1d5 | PAL | Pallidum | 1.34 | |
| 1.01 | | |||
| Tbc1d5 | RHP | Retrohippocampal region | 4.99 | |
| 3.76 | | |||
| Tbc1d5 | sAMY | Striatum-like amygdalar nuclei | 0.78 | |
| 0.49 | | |||
| Tbc1d5 | STR | Striatum | 1.95 | |
| 1.48 | | |||
| Tbc1d5 | STRd | Striatum dorsal region | 2.23 | |
| 1.8 | | |||
| Tbc1d5 | STRv | Striatum ventral region | 1.77 | |
| 1.08 | | |||
| Tbc1d5 | TH | Thalamus | 1.91 | |
| 1.81 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00004255 | 26 | 582 | 607 | KESEEELEAQISFLQGQLNDLDAMCK | Peptide Atlas |
| TBCD5_HUMAN_170 | 14 | 170 | 183 | TFPEMQFFQQENVR | PRIDE |
| TBCD5_HUMAN_73 | 10 | 73 | 82 | RQKGINGQLR | PRIDE |