Annotation Detail for RIMS3
Basic Information Top
| Gene Symbol: | RIMS3 ( KIAA0237,NIM3,RIM3 ) |
|---|---|
| Gene Full Name: | regulating synaptic membrane exocytosis 3 |
| Band: | 1p34.2 |
| Quick Links | Entrez ID:9783; OMIM: 611600; Uniprot ID:RIMS3_HUMAN; ENSEMBL ID: ENSG00000117016; HGNC ID: 21292 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.654808
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 2 / 62319 | 32 | |
| fetus | 11 / 564012 | 19 | |
| neonate | 0 / 31097 | 0 | |
| infant | 3 / 23620 | 127 |  |
| juvenile | 5 / 55556 | 89 | |
| adult | 34 / 1939121 | 17 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 11 / 263845 | 41 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 15 / 71755 | 209 |  |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 113 / 3360307 | 33 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 12 / 125680 | 95 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 100 / 1100989 | 90 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 8 / 211054 | 37 | |
| heart | 0 / 89626 | 0 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 0 / 24145 | 0 | |
| liver | 3 / 207743 | 14 | |
| lung | 3 / 336974 | 8 | |
| lymph | 15 / 44270 | 338 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 5 / 330442 | 15 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204730_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 19.1 | |
| Adipocyte | 4.55 | |
| AdrenalCortex | 5.1 | |
| Adrenalgland | 4 | |
| Amygdala | 245.75 | |
| Appendix | 4.85 | |
| AtrioventricularNode | 3.65 | |
| BDCA4+_DentriticCells | 92.15 | |
| Bonemarrow | 4.7 | |
| BronchialEpithelialCells | 4.5 | |
| CD105+_Endothelial | 23.55 | |
| CD14+_Monocytes | 4.85 | |
| CD19+_BCells(neg._sel.) | 4.95 | |
| CD33+_Myeloid | 5.85 | |
| CD34+ | 12.75 | |
| CD4+_Tcells | 4.8 | |
| CD56+_NKCells | 5.35 | |
| CD71+_EarlyErythroid | 4.35 | |
| CD8+_Tcells | 4.3 | |
| CardiacMyocytes | 6.15 | |
| Caudatenucleus | 117.7 | |
| Cerebellum | 234.45 | |
| CerebellumPeduncles | 354.15 | |
| CiliaryGanglion | 3.45 | |
| CingulateCortex | 727 | |
| Colorectaladenocarcinoma | 4.6 | |
| DorsalRootGanglion | 3.6 | |
| FetalThyroid | 7.1 | |
| Fetalbrain | 110.55 | |
| Fetalliver | 4.1 | |
| Fetallung | 3.7 | |
| GlobusPallidus | 299.4 | |
| Heart | 5.95 | |
| Hypothalamus | 579.65 | |
| Kidney | 3.85 | |
| Leukemia_chronicMyelogenousK-562 | 4.15 | |
| Leukemia_promyelocytic-HL-60 | 55.45 | |
| Leukemialymphoblastic(MOLT-4) | 21.35 | |
| Liver | 6.1 | |
| Lung | 7.8 | |
| Lymphnode | 3.85 | |
| Lymphoma_burkitts(Daudi) | 556.95 | |
| Lymphoma_burkitts(Raji) | 143.35 | |
| MedullaOblongata | 422.1 | |
| OccipitalLobe | 498.7 | |
| OlfactoryBulb | 3.7 | |
| Ovary | 3.05 | |
| Pancreas | 3.65 | |
| PancreaticIslet | 5.3 | |
| ParietalLobe | 451.9 | |
| Pituitary | 5.45 | |
| Placenta | 5.3 | |
| Pons | 217.45 | |
| PrefrontalCortex | 1189.05 |  |
| Prostate | 5.35 | |
| Salivarygland | 3.7 | |
| SkeletalMuscle | 5.5 | |
| Skin | 3.6 | |
| SmoothMuscle | 5.15 | |
| Spinalcord | 23.15 | |
| SubthalamicNucleus | 405.1 | |
| SuperiorCervicalGanglion | 6.25 | |
| TemporalLobe | 449.5 | |
| Testis | 4 | |
| TestisGermCell | 3.8 | |
| TestisIntersitial | 3.8 | |
| TestisLeydigCell | 4.6 | |
| TestisSeminiferousTubule | 4 | |
| Thalamus | 1300.2 | |
| Thymus | 3.75 | |
| Thyroid | 5.7 | |
| Tongue | 4.45 | |
| Tonsil | 4.55 | |
| Trachea | 3.9 | |
| TrigeminalGanglion | 8.9 | |
| Uterus | 3.75 | |
| UterusCorpus | 4.25 | |
| WholeBlood | 4.95 | |
| Wholebrain | 952.6 | |
| colon | 5 | |
| pineal_day | 54.02 | |
| pineal_night | 93.02 | |
| retina | 30.475 | |
| small_intestine | 4.35 | |
- Probe name: CUST_12382_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.86 ± 1.01 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.46 ± 0.48 | |
| Basal Part of Pons | 3.44 ± 0.55 | |
| Cerebellar Cortex | 4.05 ± 0.49 | |
| Cerebellar Nuclei | 3.5 ± 0.6 | |
| Claustrum | 5.08 ± 0.47 | |
| Epithalamus | 3.4 ± 0.69 | |
| Frontal Lobe | 4.1 ± 0.63 | |
| Globus Pallidus | 2.39 ± 0.66 | |
| Hypothalamus | 3.87 ± 0.76 | |
| Insula | 4.47 ± 0.35 | |
| Limbic Lobe | 3.51 ± 0.62 | |
| Mesencephalon | 3.99 ± 0.74 | |
| Myelencephalon | 3.97 ± 0.78 | |
| Occipital Lobe | 3.78 ± 0.77 | |
| Parietal Lobe | 4.3 ± 0.62 | |
| Pontine Tegmentum | 3.89 ± 0.77 | |
| Striatum | 2.78 ± 0.94 | |
| Subthalamus | 3.63 ± 0.43 | |
| Temporal Lobe | 4.09 ± 0.57 | |
| Thalamus | 4.55 ± 0.57 | |
| White Matter | 2.29 ± 0.54 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Rims3 | CB | Cerebellum | 100 | |
| 100 | | |||
| Rims3 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Rims3 | HIP | Hippocampal region | 24.51 | |
| 31.83 | | |||
| Rims3 | HPF | Hippocampal formation | 35.87 | |
| 41.22 | | |||
| Rims3 | HY | Hypothalamus | 91.01 | |
| 97.26 | | |||
| Rims3 | LSX | Lateral septal complex | 14.58 | |
| 13.46 | | |||
| Rims3 | MB | Midbrain | 90.95 | |
| 100 | | |||
| Rims3 | MY | Medulla | 30.61 | |
| 37.74 | | |||
| Rims3 | OLF | Olfactory bulb | 57.96 | |
| 69.29 | | |||
| Rims3 | P | Pons | 42.14 | |
| 52.96 | | |||
| Rims3 | PAL | Pallidum | 65.97 | |
| 71.61 | | |||
| Rims3 | RHP | Retrohippocampal region | 57 | |
| 56.52 | | |||
| Rims3 | sAMY | Striatum-like amygdalar nuclei | 72.32 | |
| 71.58 | | |||
| Rims3 | STR | Striatum | 33.27 | |
| 31.11 | | |||
| Rims3 | STRd | Striatum dorsal region | 27.7 | |
| 26.23 | | |||
| Rims3 | STRv | Striatum ventral region | 44.21 | |
| 36.81 | | |||
| Rims3 | TH | Thalamus | 100 | |
| 100 | |
Peptide