AutismKB 2.0

Annotation Detail for MTSS1


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Basic Information Top
Gene Symbol:MTSS1 ( DKFZp781P2223,FLJ44694,KIAA0429,MIM,MIMA,MIMB )
Gene Full Name: metastasis suppressor 1
Band: 8q24.13
Quick LinksEntrez ID:9788; OMIM: 608486; Uniprot ID:MTSS1_HUMAN; ENSEMBL ID: ENSG00000170873; HGNC ID: 20443
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus51 / 56401290
neonate0 / 310970 
infant1 / 2362042
juvenile3 / 5555653
adult87 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma12 / 106883112
head and neck tumor23 / 136302168
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor8 / 9635983
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal221 / 336030765
ovarian tumor3 / 7668239
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder2 / 2975767
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain112 / 1100989101
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye14 / 21105466
heart10 / 89626111
intestine3 / 23447212
kidney14 / 21177766
larynx3 / 24145124
liver13 / 20774362
lung21 / 33697462
lymph0 / 442700 
lymph node3 / 9161032
mammary gland1 / 1532716
mouth19 / 67052283
muscle3 / 10771527
nerve2 / 15768126
ovary3 / 10205129
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta15 / 28082553
prostate5 / 18934526
salivary gland0 / 201550 
skin7 / 21057433
spleen6 / 53952111
stomach0 / 966190 
testis21 / 33044263
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210360_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.1
Adipocyte4.15
AdrenalCortex4.55
Adrenalgland3.6
Amygdala4.4
Appendix4.4
AtrioventricularNode3.25
BDCA4+_DentriticCells4.6
Bonemarrow4.1
BronchialEpithelialCells4.1
CD105+_Endothelial4.2
CD14+_Monocytes4.45
CD19+_BCells(neg._sel.)4.5
CD33+_Myeloid5.35
CD34+5.25
CD4+_Tcells4.55
CD56+_NKCells5.35
CD71+_EarlyErythroid3.85
CD8+_Tcells4.05
CardiacMyocytes5.55
Caudatenucleus3.7
Cerebellum3.4
CerebellumPeduncles4.9
CiliaryGanglion2.9
CingulateCortex4.35
Colorectaladenocarcinoma4.2
DorsalRootGanglion3.25
FetalThyroid4.05
Fetalbrain4.2
Fetalliver3.7
Fetallung3.45
GlobusPallidus3.1
Heart5.45
Hypothalamus4.5
Kidney3.45
Leukemia_chronicMyelogenousK-5623.8
Leukemia_promyelocytic-HL-603.7
Leukemialymphoblastic(MOLT-4)3.35
Liver5.55
Lung4.6
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.35
Lymphoma_burkitts(Raji)5.95
MedullaOblongata3.8
OccipitalLobe3.8
OlfactoryBulb3.3
Ovary2.75
Pancreas3.4
PancreaticIslet4.45
ParietalLobe4.45
Pituitary4.9
Placenta4.25
Pons4.1
PrefrontalCortex5.2
Prostate4.9
Salivarygland3.35
SkeletalMuscle4.9
Skin3.2
SmoothMuscle4.8
Spinalcord4.45
SubthalamicNucleus3.8
SuperiorCervicalGanglion4.8
TemporalLobe3.85
Testis3.65
TestisGermCell3.5
TestisIntersitial3.5
TestisLeydigCell4.25
TestisSeminiferousTubule3.6
Thalamus4.25
Thymus3.3
Thyroid5.15
Tongue4.1
Tonsil4.05
Trachea3.5
TrigeminalGanglion4.6
Uterus3.4
UterusCorpus3.75
WholeBlood4.6
Wholebrain3.55
colon4.2
pineal_day5.22
pineal_night5.12
retina5.175
small_intestine4.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1533_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.16 ± 1.15
Basal Forebrain2.68 ± 0.46
Basal Part of Pons2.49 ± 0.55
Cerebellar Cortex3.47 ± 0.44
Cerebellar Nuclei3.21 ± 0.7
Claustrum3.3 ± 0.69
Epithalamus2.58 ± 0.88
Frontal Lobe2.7 ± 0.72
Globus Pallidus3.24 ± 0.89
Hypothalamus2.63 ± 0.79
Insula2.42 ± 0.7
Limbic Lobe2.66 ± 0.69
Mesencephalon2.95 ± 0.74
Myelencephalon2.78 ± 0.68
Occipital Lobe2.59 ± 0.79
Parietal Lobe2.77 ± 0.84
Pontine Tegmentum2.87 ± 0.83
Striatum2.88 ± 0.94
Subthalamus3.19 ± 1.02
Temporal Lobe2.62 ± 0.72
Thalamus2.86 ± 0.59
White Matter4.25 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mtss1CBCerebellum31.05
87.19
Mtss1CTXCerebral cortex13.43
9.24
Mtss1HIPHippocampal region31.74
21.93
Mtss1HPFHippocampal formation24.75
16.37
Mtss1HYHypothalamus21.3
12.75
Mtss1LSXLateral septal complex19.56
10.42
Mtss1MBMidbrain22.81
16.43
Mtss1MYMedulla37.8
31.68
Mtss1OLFOlfactory bulb26.5
15.57
Mtss1PPons32.61
24.88
Mtss1PALPallidum13.73
8.95
Mtss1RHPRetrohippocampal region13.38
9.08
Mtss1sAMYStriatum-like amygdalar nuclei12.68
7.55
Mtss1STRStriatum8.67
4.88
Mtss1STRdStriatum dorsal region3.76
2.28
Mtss1STRvStriatum ventral region16.54
8.32
Mtss1THThalamus22.94
14.68
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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