AutismKB 2.0

Annotation Detail for SERTAD2


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Basic Information Top
Gene Symbol:SERTAD2 ( MGC126688,MGC126690,Sei-2,TRIP-Br2 )
Gene Full Name: SERTA domain containing 2
Band: 2p14
Quick LinksEntrez ID:9792; OMIM: NA; Uniprot ID:SRTD2_HUMAN; ENSEMBL ID: ENSG00000179833; HGNC ID: 30784
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus39 / 56401269
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor6 / 11424652
esophageal tumor2 / 17290115
gastrointestinal tumor2 / 11936916
germ cell tumor12 / 26384545
glioma3 / 10688328
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal147 / 336030743
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood7 / 12347856
bone8 / 71655111
bone marrow4 / 4880181
brain16 / 110098914
cervix2 / 4817141
connective tissue7 / 14925546
ear1 / 1621261
embryonic tissue8 / 21572237
esophagus2 / 2020998
eye6 / 21105428
heart10 / 89626111
intestine7 / 23447229
kidney14 / 21177766
larynx1 / 2414541
liver5 / 20774324
lung10 / 33697429
lymph0 / 442700 
lymph node10 / 91610109
mammary gland3 / 15327119
mouth3 / 6705244
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas2 / 2148129
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta9 / 28082532
prostate6 / 18934531
salivary gland0 / 201550 
skin17 / 21057480
spleen0 / 539520 
stomach6 / 9661962
testis5 / 33044215
thymus9 / 81131110
thyroid0 / 474730 
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord0 / 136800 
uterus11 / 23287847
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202656_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts126.9
Adipocyte14.85
AdrenalCortex6.4
Adrenalgland5.35
Amygdala4.6
Appendix6.75
AtrioventricularNode4.25
BDCA4+_DentriticCells372.9
Bonemarrow53.35
BronchialEpithelialCells14.8
CD105+_Endothelial28.15
CD14+_Monocytes50.65
CD19+_BCells(neg._sel.)211.6
CD33+_Myeloid320.45
CD34+122
CD4+_Tcells61.25
CD56+_NKCells105.85
CD71+_EarlyErythroid300.6
CD8+_Tcells74.75
CardiacMyocytes7.35
Caudatenucleus4.6
Cerebellum6.1
CerebellumPeduncles10.6
CiliaryGanglion4.6
CingulateCortex5.9
Colorectaladenocarcinoma6.75
DorsalRootGanglion4.9
FetalThyroid7.25
Fetalbrain7.5
Fetalliver9.15
Fetallung7.25
GlobusPallidus4.85
Heart6.15
Hypothalamus7.2
Kidney3.75
Leukemia_chronicMyelogenousK-5627.05
Leukemia_promyelocytic-HL-6028.15
Leukemialymphoblastic(MOLT-4)15.05
Liver7.2
Lung7.25
Lymphnode11.35
Lymphoma_burkitts(Daudi)39.8
Lymphoma_burkitts(Raji)16.45
MedullaOblongata7.15
OccipitalLobe5.9
OlfactoryBulb7.75
Ovary4.55
Pancreas4.65
PancreaticIslet6.8
ParietalLobe6.95
Pituitary7.55
Placenta63.45
Pons6.45
PrefrontalCortex8.85
Prostate17.95
Salivarygland10.55
SkeletalMuscle7.4
Skin7
SmoothMuscle23.6
Spinalcord4.85
SubthalamicNucleus6
SuperiorCervicalGanglion7.4
TemporalLobe6.1
Testis5.45
TestisGermCell21.95
TestisIntersitial5.6
TestisLeydigCell6.4
TestisSeminiferousTubule6.4
Thalamus6.35
Thymus98.2
Thyroid8.25
Tongue7.55
Tonsil36.65
Trachea18.95
TrigeminalGanglion6.75
Uterus12.45
UterusCorpus9.65
WholeBlood14.3
Wholebrain5.8
colon11.75
pineal_day63.56
pineal_night88.62
retina43.15
small_intestine17.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P56949
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.81 ± 0.34
Basal Forebrain5.95 ± 0.1
Basal Part of Pons5.66 ± 0.3
Cerebellar Cortex5.87 ± 0.3
Cerebellar Nuclei5.98 ± 0.49
Claustrum5.82 ± 0.59
Epithalamus5.95 ± 0.28
Frontal Lobe5.73 ± 0.35
Globus Pallidus6.19 ± 0.38
Hypothalamus5.72 ± 0.51
Insula5.63 ± 0.77
Limbic Lobe5.94 ± 0.46
Mesencephalon5.81 ± 0.44
Myelencephalon5.88 ± 0.45
Occipital Lobe6.4 ± 0.39
Parietal Lobe5.82 ± 0.37
Pontine Tegmentum5.98 ± 0.46
Striatum6.25 ± 0.34
Subthalamus5.8 ± 0.28
Temporal Lobe5.83 ± 0.35
Thalamus5.83 ± 0.41
White Matter7.12 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sertad2CBCerebellum27.97
38.48
Sertad2CTXCerebral cortex41.53
32.51
Sertad2HIPHippocampal region24.12
33.62
Sertad2HPFHippocampal formation29.31
33.46
Sertad2HYHypothalamus5.54
4.5
Sertad2LSXLateral septal complex8.68
8.75
Sertad2MBMidbrain5.92
6.71
Sertad2MYMedulla17.14
20.17
Sertad2OLFOlfactory bulb40.95
35.83
Sertad2PPons8.12
9.25
Sertad2PALPallidum10.53
9.79
Sertad2RHPRetrohippocampal region39.8
35.07
Sertad2sAMYStriatum-like amygdalar nuclei8.71
7.57
Sertad2STRStriatum23.31
18.64
Sertad2STRdStriatum dorsal region24.95
18.76
Sertad2STRvStriatum ventral region34.07
27.37
Sertad2THThalamus11.41
11.38
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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