AutismKB 2.0

Annotation Detail for CKAP5


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Basic Information Top
Gene Symbol:CKAP5 ( CHTOG,FLJ35359,KIAA0097,MSPS,TOG,TOGp,ch-TOG )
Gene Full Name: cytoskeleton associated protein 5
Band: 11p11.2
Quick LinksEntrez ID:9793; OMIM: 611142; Uniprot ID:CKAP5_HUMAN; ENSEMBL ID: ENSG00000175216; HGNC ID: 28959
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst23 / 62319369
fetus77 / 564012136
neonate1 / 3109732
infant0 / 236200 
juvenile5 / 5555689
adult202 / 1939121104
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor13 / 94178138
cervical tumor4 / 34366116
chondrosarcoma13 / 82823156
colorectal tumor19 / 114246166
esophageal tumor1 / 1729057
gastrointestinal tumor11 / 11936992
germ cell tumor42 / 263845159
glioma7 / 10688365
head and neck tumor5 / 13630236
kidney tumor4 / 6895958
leukemia6 / 9584262
liver tumor11 / 96359114
lung tumor8 / 10312777
lymphoma6 / 7175583
non-neoplasia2 / 9725020
normal306 / 336030791
ovarian tumor6 / 7668278
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer9 / 10268087
retinoblastoma7 / 46356151
skin tumor14 / 124949112
soft tissue/muscle tissue tumor21 / 125191167
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites2 / 4001549
bladder4 / 29757134
blood5 / 12347840
bone9 / 71655125
bone marrow3 / 4880161
brain114 / 1100989103
cervix4 / 4817183
connective tissue12 / 14925580
ear9 / 16212555
embryonic tissue47 / 215722217
esophagus1 / 2020949
eye19 / 21105490
heart16 / 89626178
intestine33 / 234472140
kidney24 / 211777113
larynx0 / 241450 
liver22 / 207743105
lung26 / 33697477
lymph2 / 4427045
lymph node8 / 9161087
mammary gland27 / 153271176
mouth1 / 6705214
muscle9 / 10771583
nerve1 / 1576863
ovary5 / 10205148
pancreas6 / 21481227
parathyroid4 / 20539194
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta5 / 28082517
prostate19 / 189345100
salivary gland1 / 2015549
skin15 / 21057471
spleen3 / 5395255
stomach6 / 9661962
testis88 / 330442266
thymus2 / 8113124
thyroid6 / 47473126
tonsil1 / 1699958
trachea4 / 5241376
umbilical cord0 / 136800 
uterus25 / 232878107
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212832_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts387.55
Adipocyte32.45
AdrenalCortex28.85
Adrenalgland47.85
Amygdala76.15
Appendix11.7
AtrioventricularNode26.05
BDCA4+_DentriticCells36.4
Bonemarrow22.95
BronchialEpithelialCells101.25
CD105+_Endothelial206.95
CD14+_Monocytes34.05
CD19+_BCells(neg._sel.)17.65
CD33+_Myeloid31.25
CD34+143.85
CD4+_Tcells42.65
CD56+_NKCells39.85
CD71+_EarlyErythroid221.2
CD8+_Tcells47.2
CardiacMyocytes67.65
Caudatenucleus106.05
Cerebellum34.3
CerebellumPeduncles49.15
CiliaryGanglion14.45
CingulateCortex124.55
Colorectaladenocarcinoma52.9
DorsalRootGanglion20.85
FetalThyroid20.4
Fetalbrain231.65
Fetalliver65.2
Fetallung53
GlobusPallidus38.35
Heart13.15
Hypothalamus145.8
Kidney16.1
Leukemia_chronicMyelogenousK-562130.45
Leukemia_promyelocytic-HL-60279.5
Leukemialymphoblastic(MOLT-4)269.65
Liver12.5
Lung12.3
Lymphnode21.55
Lymphoma_burkitts(Daudi)300.9
Lymphoma_burkitts(Raji)60.2
MedullaOblongata67.15
OccipitalLobe75
OlfactoryBulb38.4
Ovary13.15
Pancreas23.65
PancreaticIslet24.05
ParietalLobe62.2
Pituitary62.15
Placenta32
Pons37.8
PrefrontalCortex271.85
Prostate25.8
Salivarygland15
SkeletalMuscle20.1
Skin13.75
SmoothMuscle78.45
Spinalcord155.5
SubthalamicNucleus111.6
SuperiorCervicalGanglion18.55
TemporalLobe52.45
Testis89.95
TestisGermCell90.4
TestisIntersitial81.15
TestisLeydigCell61.9
TestisSeminiferousTubule81.4
Thalamus133.9
Thymus59.1
Thyroid20.15
Tongue29.65
Tonsil44
Trachea16.15
TrigeminalGanglion18.85
Uterus21.05
UterusCorpus11.95
WholeBlood15.95
Wholebrain41.95
colon21.65
pineal_day133.32
pineal_night125.9
retina60.875
small_intestine25.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P300841
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.03 ± 0.6
Basal Forebrain5.04 ± 0.26
Basal Part of Pons5.21 ± 0.33
Cerebellar Cortex5.4 ± 0.32
Cerebellar Nuclei5 ± 0.39
Claustrum5.45 ± 0.5
Epithalamus5.18 ± 0.32
Frontal Lobe5.2 ± 0.39
Globus Pallidus4.99 ± 0.31
Hypothalamus4.87 ± 0.48
Insula5.17 ± 0.27
Limbic Lobe5.13 ± 0.43
Mesencephalon5.2 ± 0.41
Myelencephalon5.08 ± 0.45
Occipital Lobe5.09 ± 0.35
Parietal Lobe5.12 ± 0.41
Pontine Tegmentum5.11 ± 0.46
Striatum4.84 ± 0.29
Subthalamus5.02 ± 0.35
Temporal Lobe5.2 ± 0.44
Thalamus5.17 ± 0.36
White Matter5.07 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ckap5CBCerebellum32.51
79.67
Ckap5CTXCerebral cortex100
85.73
Ckap5HIPHippocampal region49.58
78.3
Ckap5HPFHippocampal formation57.32
69.58
Ckap5HYHypothalamus37.91
31.8
Ckap5LSXLateral septal complex28.72
22
Ckap5MBMidbrain58.81
57.86
Ckap5MYMedulla45.63
54.8
Ckap5OLFOlfactory bulb58.36
50.83
Ckap5PPons53.56
64.14
Ckap5PALPallidum45.36
45.23
Ckap5RHPRetrohippocampal region70.91
60.06
Ckap5sAMYStriatum-like amygdalar nuclei33.7
26.09
Ckap5STRStriatum48.9
36.5
Ckap5STRdStriatum dorsal region54.45
41.19
Ckap5STRvStriatum ventral region43.82
30.45
Ckap5THThalamus66.18
65.37
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CKAP5_HUMAN_1469 13 1469 1481 SMSGHPEAAQMVR PRIDE
PAp00003911 22 1715 1736 ILDHLTMIDNKNESELEAHLCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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