AutismKB 2.0

Annotation Detail for PHYHIP


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Basic Information Top
Gene Symbol:PHYHIP ( DYRK1AP3,KIAA0273,PAHX-AP,PAHXAP1 )
Gene Full Name: phytanoyl-CoA 2-hydroxylase interacting protein
Band: 8p21.3
Quick LinksEntrez ID:9796; OMIM: 608511; Uniprot ID:PHYIP_HUMAN; ENSEMBL ID: ENSG00000168490; HGNC ID: 16865
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus17 / 56401230
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult58 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal137 / 336030740
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain169 / 1100989153
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland1 / 2015549
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205325_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte5.5
AdrenalCortex23.05
Adrenalgland15.15
Amygdala139
Appendix5.4
AtrioventricularNode4
BDCA4+_DentriticCells4.8
Bonemarrow5.3
BronchialEpithelialCells5.35
CD105+_Endothelial5.45
CD14+_Monocytes4.85
CD19+_BCells(neg._sel.)5.25
CD33+_Myeloid6.2
CD34+6.85
CD4+_Tcells5.9
CD56+_NKCells6.45
CD71+_EarlyErythroid5.05
CD8+_Tcells4.1
CardiacMyocytes6.75
Caudatenucleus179.25
Cerebellum134.1
CerebellumPeduncles241.15
CiliaryGanglion3.75
CingulateCortex150.3
Colorectaladenocarcinoma5.45
DorsalRootGanglion4.1
FetalThyroid5.25
Fetalbrain33.65
Fetalliver4.7
Fetallung4.55
GlobusPallidus124.85
Heart10.6
Hypothalamus41.45
Kidney7.85
Leukemia_chronicMyelogenousK-5624.9
Leukemia_promyelocytic-HL-604.75
Leukemialymphoblastic(MOLT-4)4.35
Liver7.05
Lung5.95
Lymphnode4.65
Lymphoma_burkitts(Daudi)6.85
Lymphoma_burkitts(Raji)7.5
MedullaOblongata165.9
OccipitalLobe105.05
OlfactoryBulb4.3
Ovary6.25
Pancreas4.3
PancreaticIslet5.8
ParietalLobe122.1
Pituitary16.7
Placenta6.55
Pons146.9
PrefrontalCortex657.8
Prostate6.45
Salivarygland4.3
SkeletalMuscle8.55
Skin5
SmoothMuscle6.25
Spinalcord13.15
SubthalamicNucleus224.65
SuperiorCervicalGanglion6.4
TemporalLobe177.2
Testis6.45
TestisGermCell8.85
TestisIntersitial4.8
TestisLeydigCell5.35
TestisSeminiferousTubule6.05
Thalamus50.15
Thymus4.25
Thyroid6.9
Tongue5.25
Tonsil5.3
Trachea4.55
TrigeminalGanglion5.25
Uterus7.4
UterusCorpus4.8
WholeBlood4.9
Wholebrain220.4
colon5.4
pineal_day6.98
pineal_night8.02
retina7.025
small_intestine5.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P433229
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.04 ± 0.9
Basal Forebrain9.44 ± 0.71
Basal Part of Pons10.65 ± 0.27
Cerebellar Cortex10.16 ± 0.29
Cerebellar Nuclei9.2 ± 0.98
Claustrum9.82 ± 0.84
Epithalamus8.85 ± 0.7
Frontal Lobe9.88 ± 0.6
Globus Pallidus6.76 ± 0.91
Hypothalamus9.51 ± 0.7
Insula9.99 ± 0.35
Limbic Lobe10.03 ± 0.95
Mesencephalon8.98 ± 0.78
Myelencephalon9.51 ± 0.95
Occipital Lobe8.97 ± 1
Parietal Lobe9.77 ± 0.68
Pontine Tegmentum9.64 ± 0.61
Striatum9.62 ± 0.85
Subthalamus9.7 ± 0.06
Temporal Lobe10.15 ± 0.6
Thalamus8.94 ± 0.53
White Matter6.49 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PhyhipCBCerebellum100
100
PhyhipCTXCerebral cortex100
100
PhyhipHIPHippocampal region100
100
PhyhipHPFHippocampal formation100
100
PhyhipHYHypothalamus73.9
73.58
PhyhipLSXLateral septal complex100
100
PhyhipMBMidbrain70.22
76.19
PhyhipMYMedulla74.14
96.98
PhyhipOLFOlfactory bulb100
100
PhyhipPPons63.24
82.9
PhyhipPALPallidum74.08
86.95
PhyhipRHPRetrohippocampal region100
100
PhyhipsAMYStriatum-like amygdalar nuclei100
100
PhyhipSTRStriatum100
100
PhyhipSTRdStriatum dorsal region100
100
PhyhipSTRvStriatum ventral region100
100
PhyhipTHThalamus60.48
64.23
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00065392 12 252 263 DRLPLLDIACNK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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