AutismKB 2.0

Annotation Detail for MRPL19


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Basic Information Top
Gene Symbol:MRPL19 ( KIAA0104,L19mt,MGC20675,MRP-L15,MRP-L19,MRPL15,RLX1,RPML15 )
Gene Full Name: mitochondrial ribosomal protein L19
Band: 2p12
Quick LinksEntrez ID:9801; OMIM: 611832; Uniprot ID:RM19_HUMAN; ENSEMBL ID: ENSG00000115364; HGNC ID: 14052
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus24 / 56401242
neonate0 / 310970 
infant1 / 2362042
juvenile4 / 5555671
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor8 / 26384530
glioma4 / 10688337
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal155 / 336030746
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone1 / 7165513
bone marrow4 / 4880181
brain50 / 110098945
cervix4 / 4817183
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus1 / 2020949
eye3 / 21105414
heart3 / 8962633
intestine15 / 23447263
kidney29 / 211777136
larynx2 / 2414582
liver9 / 20774343
lung12 / 33697435
lymph1 / 4427022
lymph node10 / 91610109
mammary gland6 / 15327139
mouth1 / 6705214
muscle9 / 10771583
nerve1 / 1576863
ovary1 / 1020519
pancreas10 / 21481246
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta18 / 28082564
prostate10 / 18934552
salivary gland1 / 2015549
skin8 / 21057437
spleen2 / 5395237
stomach2 / 9661920
testis7 / 33044221
thymus2 / 8113124
thyroid2 / 4747342
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203465_at
Cell line Expression level Expression bar
721_B_lymphoblasts175.45
Adipocyte20.7
AdrenalCortex26.65
Adrenalgland16.55
Amygdala30.3
Appendix25
AtrioventricularNode20.6
BDCA4+_DentriticCells32.95
Bonemarrow17.9
BronchialEpithelialCells63.2
CD105+_Endothelial74.5
CD14+_Monocytes19.95
CD19+_BCells(neg._sel.)22.45
CD33+_Myeloid22.95
CD34+40.1
CD4+_Tcells17.95
CD56+_NKCells28.55
CD71+_EarlyErythroid17.65
CD8+_Tcells15.55
CardiacMyocytes32.85
Caudatenucleus16.1
Cerebellum10.85
CerebellumPeduncles21.3
CiliaryGanglion16.95
CingulateCortex19.6
Colorectaladenocarcinoma45.1
DorsalRootGanglion17.9
FetalThyroid18.25
Fetalbrain16.4
Fetalliver17.3
Fetallung12.55
GlobusPallidus15.35
Heart30
Hypothalamus24.55
Kidney17.75
Leukemia_chronicMyelogenousK-56219.05
Leukemia_promyelocytic-HL-6021.8
Leukemialymphoblastic(MOLT-4)14.4
Liver27.6
Lung17.35
Lymphnode12.3
Lymphoma_burkitts(Daudi)25.8
Lymphoma_burkitts(Raji)51.45
MedullaOblongata16.6
OccipitalLobe16.5
OlfactoryBulb13.75
Ovary14.05
Pancreas14.65
PancreaticIslet20.1
ParietalLobe19.9
Pituitary21.35
Placenta15
Pons18.35
PrefrontalCortex25.85
Prostate25.8
Salivarygland15.6
SkeletalMuscle28.1
Skin17.4
SmoothMuscle23.25
Spinalcord19.2
SubthalamicNucleus19.4
SuperiorCervicalGanglion28.4
TemporalLobe17.65
Testis13.75
TestisGermCell14.15
TestisIntersitial14.1
TestisLeydigCell19.05
TestisSeminiferousTubule16.1
Thalamus18.4
Thymus12.8
Thyroid43.45
Tongue21.9
Tonsil17.75
Trachea13.5
TrigeminalGanglion25.5
Uterus18.2
UterusCorpus21.6
WholeBlood17.65
Wholebrain16.25
colon66.1
pineal_day21.1
pineal_night28.7
retina20.35
small_intestine82.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5646_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.59 ± 0.21
Basal Forebrain8.52 ± 0.23
Basal Part of Pons8.32 ± 0.18
Cerebellar Cortex8.3 ± 0.2
Cerebellar Nuclei8.8 ± 0.28
Claustrum8.75 ± 0.33
Epithalamus8.66 ± 0.31
Frontal Lobe8.5 ± 0.26
Globus Pallidus9.09 ± 0.12
Hypothalamus8.54 ± 0.34
Insula8.43 ± 0.23
Limbic Lobe8.51 ± 0.28
Mesencephalon8.7 ± 0.25
Myelencephalon8.56 ± 0.29
Occipital Lobe8.69 ± 0.24
Parietal Lobe8.6 ± 0.29
Pontine Tegmentum8.63 ± 0.24
Striatum8.79 ± 0.29
Subthalamus8.73 ± 0.12
Temporal Lobe8.44 ± 0.25
Thalamus8.65 ± 0.19
White Matter9.26 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mrpl19CBCerebellum6.77
7.62
Mrpl19CTXCerebral cortex5.53
3.65
Mrpl19HIPHippocampal region6.45
5.47
Mrpl19HPFHippocampal formation5.84
4.5
Mrpl19HYHypothalamus6.01
5.16
Mrpl19LSXLateral septal complex14.28
9.37
Mrpl19MBMidbrain6.86
6.03
Mrpl19MYMedulla12.28
17
Mrpl19OLFOlfactory bulb8.84
7.25
Mrpl19PPons9.26
11.89
Mrpl19PALPallidum10.5
9.1
Mrpl19RHPRetrohippocampal region4.96
3.3
Mrpl19sAMYStriatum-like amygdalar nuclei2.32
1.49
Mrpl19STRStriatum2.59
1.72
Mrpl19STRdStriatum dorsal region2.13
1.42
Mrpl19STRvStriatum ventral region2.3
1.51
Mrpl19THThalamus5.51
4.1
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00082162 11 130 140 ISQFLGICIQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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