AutismKB 2.0

Annotation Detail for TOMM20


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Basic Information Top
Gene Symbol:TOMM20 ( KIAA0016,MAS20,MGC117367,MOM19,TOM20 )
Gene Full Name: translocase of outer mitochondrial membrane 20 homolog (yeast)
Band: 1q42.3
Quick LinksEntrez ID:9804; OMIM: 601848; Uniprot ID:TOM20_HUMAN; ENSEMBL ID: ENSG00000173726; HGNC ID: 20947
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst15 / 62319240
fetus257 / 564012455
neonate10 / 31097321
infant10 / 23620423
juvenile20 / 55556359
adult511 / 1939121263
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor10 / 34366290
chondrosarcoma14 / 82823169
colorectal tumor43 / 114246376
esophageal tumor5 / 17290289
gastrointestinal tumor37 / 119369309
germ cell tumor176 / 263845667
glioma27 / 106883252
head and neck tumor75 / 136302550
kidney tumor23 / 68959333
leukemia14 / 95842146
liver tumor26 / 96359269
lung tumor6 / 10312758
lymphoma11 / 71755153
non-neoplasia12 / 97250123
normal1023 / 3360307304
ovarian tumor14 / 76682182
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS36 / 125680286
prostate cancer17 / 102680165
retinoblastoma18 / 46356388
skin tumor14 / 124949112
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue7 / 13106534
adrenal gland7 / 33197210
ascites16 / 40015399
bladder4 / 29757134
blood11 / 12347889
bone16 / 71655223
bone marrow10 / 48801204
brain637 / 1100989578
cervix10 / 48171207
connective tissue29 / 149255194
ear5 / 16212308
embryonic tissue50 / 215722231
esophagus5 / 20209247
eye40 / 211054189
heart18 / 89626200
intestine68 / 234472290
kidney59 / 211777278
larynx0 / 241450 
liver40 / 207743192
lung50 / 336974148
lymph3 / 4427067
lymph node24 / 91610261
mammary gland21 / 153271137
mouth65 / 67052969
muscle10 / 10771592
nerve4 / 15768253
ovary12 / 102051117
pancreas31 / 214812144
parathyroid10 / 20539486
pharynx4 / 4132896
pituitary gland4 / 16585241
placenta62 / 280825220
prostate34 / 189345179
salivary gland3 / 20155148
skin51 / 210574242
spleen9 / 53952166
stomach20 / 96619206
testis187 / 330442565
thymus32 / 81131394
thyroid13 / 47473273
tonsil0 / 169990 
trachea51 / 52413973
umbilical cord3 / 13680219
uterus47 / 232878201
vascular17 / 51780328
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212773_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1050.95
Adipocyte245.5
AdrenalCortex198.7
Adrenalgland188.5
Amygdala319.85
Appendix133.6
AtrioventricularNode37.25
BDCA4+_DentriticCells966.85
Bonemarrow150.6
BronchialEpithelialCells645.95
CD105+_Endothelial732.9
CD14+_Monocytes766.75
CD19+_BCells(neg._sel.)1793.7
CD33+_Myeloid788.65
CD34+1191.1
CD4+_Tcells987.3
CD56+_NKCells657.3
CD71+_EarlyErythroid218.9
CD8+_Tcells901
CardiacMyocytes431.4
Caudatenucleus96.7
Cerebellum121.95
CerebellumPeduncles131.1
CiliaryGanglion28.75
CingulateCortex111.95
Colorectaladenocarcinoma232.25
DorsalRootGanglion39.55
FetalThyroid187.35
Fetalbrain160.35
Fetalliver210.2
Fetallung258.7
GlobusPallidus54.1
Heart157.6
Hypothalamus210.3
Kidney143.15
Leukemia_chronicMyelogenousK-562881.1
Leukemia_promyelocytic-HL-60630.4
Leukemialymphoblastic(MOLT-4)310.35
Liver286.6
Lung499
Lymphnode309.05
Lymphoma_burkitts(Daudi)745.4
Lymphoma_burkitts(Raji)1896.5
MedullaOblongata190.8
OccipitalLobe175.65
OlfactoryBulb167.55
Ovary166.45
Pancreas223.8
PancreaticIslet506.1
ParietalLobe161.75
Pituitary492.3
Placenta272.8
Pons165.55
PrefrontalCortex320.7
Prostate684.5
Salivarygland247.5
SkeletalMuscle43.1
Skin67
SmoothMuscle558.6
Spinalcord138.3
SubthalamicNucleus114.1
SuperiorCervicalGanglion129.65
TemporalLobe211.35
Testis281.9
TestisGermCell246.85
TestisIntersitial278.55
TestisLeydigCell196.5
TestisSeminiferousTubule167.45
Thalamus149.75
Thymus394.5
Thyroid659.4
Tongue227.1
Tonsil221.15
Trachea211.55
TrigeminalGanglion47.95
Uterus549
UterusCorpus59.7
WholeBlood424.05
Wholebrain290.85
colon391.85
pineal_day428.7
pineal_night472.92
retina308.575
small_intestine357.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P216765
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.2 ± 0.39
Basal Forebrain10.29 ± 0.26
Basal Part of Pons10.81 ± 0.19
Cerebellar Cortex10.12 ± 0.16
Cerebellar Nuclei10.45 ± 0.49
Claustrum10.12 ± 0.59
Epithalamus10.33 ± 0.23
Frontal Lobe10.62 ± 0.28
Globus Pallidus10.16 ± 0.38
Hypothalamus10.73 ± 0.14
Insula10.58 ± 0.25
Limbic Lobe10.29 ± 0.54
Mesencephalon10.28 ± 0.35
Myelencephalon10.36 ± 0.48
Occipital Lobe9.95 ± 0.6
Parietal Lobe10.5 ± 0.4
Pontine Tegmentum10.44 ± 0.34
Striatum10.06 ± 0.51
Subthalamus10.92 ± 0.34
Temporal Lobe10.59 ± 0.31
Thalamus10.23 ± 0.34
White Matter10.44 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tomm20CBCerebellum48.41
100
Tomm20CTXCerebral cortex100
100
Tomm20HIPHippocampal region100
100
Tomm20HPFHippocampal formation100
100
Tomm20HYHypothalamus100
100
Tomm20LSXLateral septal complex100
100
Tomm20MBMidbrain100
100
Tomm20MYMedulla99.12
100
Tomm20OLFOlfactory bulb100
100
Tomm20PPons90.87
100
Tomm20PALPallidum100
100
Tomm20RHPRetrohippocampal region100
100
Tomm20sAMYStriatum-like amygdalar nuclei100
100
Tomm20STRStriatum100
100
Tomm20STRdStriatum dorsal region100
100
Tomm20STRvStriatum ventral region100
100
Tomm20THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002391 20 69 88 FFLEEIQLGEELLAQGEYEK Peptide Atlas
TOM20_HUMAN_132 13 132 144 IVSAQSLAEDDVE PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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