AutismKB 2.0

Annotation Detail for URB2


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Basic Information Top
Gene Symbol:URB2 ( KIAA0133,MGC138837,MGC138838,NET10,NPA2 )
Gene Full Name: URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
Band: 1q42.13
Quick LinksEntrez ID:9816; OMIM: NA; Uniprot ID:URB2_HUMAN; ENSEMBL ID: ENSG00000135763; HGNC ID: 28967
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst4 / 6231964
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor7 / 26384526
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal29 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone5 / 7165569
bone marrow0 / 488010 
brain6 / 11009895
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine1 / 2344724
kidney4 / 21177718
larynx2 / 2414582
liver2 / 2077439
lung3 / 3369748
lymph3 / 4427067
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205284_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.35
Adipocyte4.1
AdrenalCortex4.3
Adrenalgland3.45
Amygdala4.35
Appendix4.15
AtrioventricularNode3.2
BDCA4+_DentriticCells4.85
Bonemarrow4
BronchialEpithelialCells4.05
CD105+_Endothelial7.55
CD14+_Monocytes4.45
CD19+_BCells(neg._sel.)4.45
CD33+_Myeloid5.75
CD34+12.8
CD4+_Tcells4.55
CD56+_NKCells5
CD71+_EarlyErythroid3.85
CD8+_Tcells4.15
CardiacMyocytes5.2
Caudatenucleus3.7
Cerebellum3.35
CerebellumPeduncles4.65
CiliaryGanglion2.9
CingulateCortex4.25
Colorectaladenocarcinoma4.15
DorsalRootGanglion3.15
FetalThyroid4
Fetalbrain4.15
Fetalliver3.65
Fetallung3.35
GlobusPallidus3.05
Heart5.2
Hypothalamus4.55
Kidney3.3
Leukemia_chronicMyelogenousK-5623.75
Leukemia_promyelocytic-HL-603.7
Leukemialymphoblastic(MOLT-4)3.4
Liver5.5
Lung4.55
Lymphnode3.55
Lymphoma_burkitts(Daudi)5.3
Lymphoma_burkitts(Raji)5.8
MedullaOblongata3.75
OccipitalLobe3.7
OlfactoryBulb3.3
Ovary2.75
Pancreas3.3
PancreaticIslet4.4
ParietalLobe4.4
Pituitary4.85
Placenta4.3
Pons3.9
PrefrontalCortex5.1
Prostate4.85
Salivarygland3.3
SkeletalMuscle5
Skin3.2
SmoothMuscle4.65
Spinalcord4.4
SubthalamicNucleus3.8
SuperiorCervicalGanglion4.65
TemporalLobe3.75
Testis4.5
TestisGermCell3.5
TestisIntersitial3.45
TestisLeydigCell4.1
TestisSeminiferousTubule3.55
Thalamus4.2
Thymus3.25
Thyroid5.2
Tongue4.1
Tonsil4.05
Trachea3.5
TrigeminalGanglion4.1
Uterus3.45
UterusCorpus3.7
WholeBlood4.45
Wholebrain3.5
colon4.2
pineal_day5.34
pineal_night5.16
retina5
small_intestine4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7474_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.19 ± 0.62
Basal Forebrain3.88 ± 0.21
Basal Part of Pons4.08 ± 0.29
Cerebellar Cortex4.28 ± 0.37
Cerebellar Nuclei3.94 ± 0.44
Claustrum4.15 ± 0.53
Epithalamus3.9 ± 0.37
Frontal Lobe3.88 ± 0.52
Globus Pallidus4.2 ± 0.5
Hypothalamus3.9 ± 0.68
Insula3.95 ± 0.45
Limbic Lobe3.88 ± 0.55
Mesencephalon3.98 ± 0.65
Myelencephalon3.9 ± 0.57
Occipital Lobe4.15 ± 0.46
Parietal Lobe3.91 ± 0.56
Pontine Tegmentum4 ± 0.53
Striatum3.89 ± 0.5
Subthalamus4.1 ± 0.9
Temporal Lobe3.9 ± 0.56
Thalamus3.99 ± 0.49
White Matter4.17 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AK122209CBCerebellum4.91
6.49
AK122209CTXCerebral cortex0.68
0.89
AK122209HIPHippocampal region1.33
1.61
AK122209HPFHippocampal formation1.14
1.24
AK122209HYHypothalamus0.07
0.12
AK122209LSXLateral septal complex0
0
AK122209MBMidbrain0.48
0.74
AK122209MYMedulla5.78
6.33
AK122209OLFOlfactory bulb0.69
0.56
AK122209PPons1.31
1.66
AK122209PALPallidum0.09
0.14
AK122209RHPRetrohippocampal region0.8
0.7
AK122209sAMYStriatum-like amygdalar nuclei0.31
0.41
AK122209STRStriatum0.24
0.25
AK122209STRdStriatum dorsal region0.24
0.25
AK122209STRvStriatum ventral region0.18
0.17
AK122209THThalamus0.65
0.78
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00026508 14 1370 1383 LHNVLFSILQCHPK Peptide Atlas
URB2_HUMAN_1044 10 1044 1053 QLENQNPQGR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018