AutismKB 2.0

Annotation Detail for CUL7


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Basic Information Top
Gene Symbol:CUL7 ( KIAA0076,dJ20C7.5 )
Gene Full Name: cullin 7
Band: 6p21.1
Quick LinksEntrez ID:9820; OMIM: 609577; Uniprot ID:CUL7_HUMAN; ENSEMBL ID: ENSG00000044090; HGNC ID: 21024
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst2 / 6231932
fetus31 / 56401254
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult93 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor15 / 26384556
glioma4 / 10688337
head and neck tumor8 / 13630258
kidney tumor6 / 6895987
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal152 / 336030745
ovarian tumor7 / 7668291
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone8 / 71655111
bone marrow6 / 48801122
brain53 / 110098948
cervix0 / 481710 
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus1 / 2020949
eye7 / 21105433
heart7 / 8962678
intestine12 / 23447251
kidney9 / 21177742
larynx1 / 2414541
liver2 / 2077439
lung24 / 33697471
lymph5 / 44270112
lymph node1 / 9161010
mammary gland9 / 15327158
mouth5 / 6705274
muscle3 / 10771527
nerve0 / 157680 
ovary14 / 102051137
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta11 / 28082539
prostate5 / 18934526
salivary gland1 / 2015549
skin8 / 21057437
spleen3 / 5395255
stomach2 / 9661920
testis18 / 33044254
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord2 / 13680146
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 36084_at
Cell line Expression level Expression bar
721_B_lymphoblasts19.4
Adipocyte6.55
AdrenalCortex7.1
Adrenalgland5.5
Amygdala6.15
Appendix6.2
AtrioventricularNode4.7
BDCA4+_DentriticCells7.05
Bonemarrow6.15
BronchialEpithelialCells6.25
CD105+_Endothelial6.2
CD14+_Monocytes8
CD19+_BCells(neg._sel.)6.7
CD33+_Myeloid9.2
CD34+11.75
CD4+_Tcells8.2
CD56+_NKCells7.5
CD71+_EarlyErythroid5.8
CD8+_Tcells6.5
CardiacMyocytes9.05
Caudatenucleus5.5
Cerebellum5.05
CerebellumPeduncles7.1
CiliaryGanglion4.35
CingulateCortex6.5
Colorectaladenocarcinoma6.25
DorsalRootGanglion4.65
FetalThyroid7
Fetalbrain7.55
Fetalliver5.3
Fetallung5.85
GlobusPallidus5.1
Heart8.65
Hypothalamus6.6
Kidney5.15
Leukemia_chronicMyelogenousK-5626.65
Leukemia_promyelocytic-HL-605.5
Leukemialymphoblastic(MOLT-4)5.05
Liver8.1
Lung6.9
Lymphnode5.4
Lymphoma_burkitts(Daudi)7.95
Lymphoma_burkitts(Raji)10.35
MedullaOblongata5.6
OccipitalLobe5.6
OlfactoryBulb4.9
Ovary4.3
Pancreas5.1
PancreaticIslet6.7
ParietalLobe7
Pituitary9.5
Placenta6.7
Pons5.9
PrefrontalCortex7.75
Prostate8.5
Salivarygland5.05
SkeletalMuscle7.65
Skin4.65
SmoothMuscle17.6
Spinalcord6.7
SubthalamicNucleus5.7
SuperiorCervicalGanglion7
TemporalLobe6.7
Testis5.35
TestisGermCell5.2
TestisIntersitial5.2
TestisLeydigCell6.3
TestisSeminiferousTubule5.35
Thalamus6.35
Thymus4.9
Thyroid7.75
Tongue6.2
Tonsil6.05
Trachea5.1
TrigeminalGanglion6.55
Uterus5.55
UterusCorpus7
WholeBlood6.7
Wholebrain5.25
colon6.2
pineal_day8.84
pineal_night8.14
retina7.425
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1664_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.42 ± 0.69
Basal Forebrain2.99 ± 0.5
Basal Part of Pons2.97 ± 0.38
Cerebellar Cortex3.69 ± 0.49
Cerebellar Nuclei3.12 ± 0.78
Claustrum3.22 ± 0.5
Epithalamus3.53 ± 0.67
Frontal Lobe3.18 ± 0.59
Globus Pallidus2.25 ± 0.45
Hypothalamus3.27 ± 0.7
Insula3.16 ± 0.56
Limbic Lobe3.38 ± 0.45
Mesencephalon3.28 ± 0.66
Myelencephalon3.3 ± 0.6
Occipital Lobe3.38 ± 0.57
Parietal Lobe3.19 ± 0.65
Pontine Tegmentum3.3 ± 0.65
Striatum3.14 ± 0.56
Subthalamus3.17 ± 0.6
Temporal Lobe3.46 ± 0.53
Thalamus3.05 ± 0.6
White Matter1.96 ± 0.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cul7CBCerebellum1.24
2.21
Cul7CTXCerebral cortex3.16
2.56
Cul7HIPHippocampal region2.12
2.44
Cul7HPFHippocampal formation2.62
2.9
Cul7HYHypothalamus12.17
11.08
Cul7LSXLateral septal complex0.11
0.06
Cul7MBMidbrain0.62
1.44
Cul7MYMedulla0.96
2.04
Cul7OLFOlfactory bulb7
6.57
Cul7PPons4.39
7.91
Cul7PALPallidum2.14
2.17
Cul7RHPRetrohippocampal region3.62
3.59
Cul7sAMYStriatum-like amygdalar nuclei8.21
6.45
Cul7STRStriatum2.71
2.17
Cul7STRdStriatum dorsal region2.4
2
Cul7STRvStriatum ventral region1.76
1.32
Cul7THThalamus0.7
0.64
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00499244 33 257 289 YLHVTSLLDQLNDSAAEPGAQNTSAPEELSGER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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