AutismKB 2.0

Annotation Detail for ARHGAP11A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ARHGAP11A ( KIAA0013,MGC70740 )
Gene Full Name: Rho GTPase activating protein 11A
Band: 15q13.3
Quick LinksEntrez ID:9824; OMIM: 610589; Uniprot ID:RHGBA_HUMAN; ENSEMBL ID: ENSG00000198826; HGNC ID: 15783
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst8 / 62319128
fetus9 / 56401215
neonate2 / 3109764
infant1 / 2362042
juvenile2 / 5555635
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor8 / 26384530
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia9 / 9584293
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma7 / 7175597
non-neoplasia0 / 972500 
normal68 / 336030720
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder3 / 29757100
blood5 / 12347840
bone5 / 7165569
bone marrow4 / 4880181
brain8 / 11009897
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine4 / 23447217
kidney5 / 21177723
larynx2 / 2414582
liver5 / 20774324
lung4 / 33697411
lymph1 / 4427022
lymph node15 / 91610163
mammary gland0 / 1532710 
mouth3 / 6705244
muscle6 / 10771555
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach1 / 9661910
testis12 / 33044236
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204492_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.05
Adipocyte6.25
AdrenalCortex7.65
Adrenalgland5.5
Amygdala6.3
Appendix9.6
AtrioventricularNode6.45
BDCA4+_DentriticCells6.35
Bonemarrow6.65
BronchialEpithelialCells6.1
CD105+_Endothelial6.35
CD14+_Monocytes6.75
CD19+_BCells(neg._sel.)6.45
CD33+_Myeloid8
CD34+7.55
CD4+_Tcells6.4
CD56+_NKCells7.05
CD71+_EarlyErythroid6.1
CD8+_Tcells5.65
CardiacMyocytes9.45
Caudatenucleus5.75
Cerebellum5.15
CerebellumPeduncles7.6
CiliaryGanglion5.1
CingulateCortex6.55
Colorectaladenocarcinoma6.35
DorsalRootGanglion5.65
FetalThyroid6.7
Fetalbrain6.05
Fetalliver5.6
Fetallung4.8
GlobusPallidus5.25
Heart9.45
Hypothalamus6.55
Kidney5.5
Leukemia_chronicMyelogenousK-5625.7
Leukemia_promyelocytic-HL-605.65
Leukemialymphoblastic(MOLT-4)5.15
Liver9.05
Lung7
Lymphnode5.25
Lymphoma_burkitts(Daudi)8.3
Lymphoma_burkitts(Raji)9.7
MedullaOblongata5.65
OccipitalLobe5.55
OlfactoryBulb4.9
Ovary4.65
Pancreas5.3
PancreaticIslet6.85
ParietalLobe7.15
Pituitary7.35
Placenta6.25
Pons6.3
PrefrontalCortex7.45
Prostate7.15
Salivarygland5.35
SkeletalMuscle9.25
Skin5.6
SmoothMuscle7.3
Spinalcord6.65
SubthalamicNucleus6
SuperiorCervicalGanglion9.05
TemporalLobe5.9
Testis5.4
TestisGermCell5.15
TestisIntersitial5.35
TestisLeydigCell7.15
TestisSeminiferousTubule5.4
Thalamus6.65
Thymus4.7
Thyroid7.55
Tongue7.05
Tonsil6.3
Trachea5.25
TrigeminalGanglion10.4
Uterus5.05
UterusCorpus6.2
WholeBlood6.8
Wholebrain5
colon6.4
pineal_day7.7
pineal_night7.56
retina7.675
small_intestine6.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P147090
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.44 ± 0.58
Basal Forebrain3.36 ± 0.66
Basal Part of Pons3.09 ± 0.51
Cerebellar Cortex3.2 ± 0.68
Cerebellar Nuclei3.33 ± 0.56
Claustrum3.51 ± 0.53
Epithalamus2.77 ± 0.72
Frontal Lobe3.1 ± 0.75
Globus Pallidus4.33 ± 0.28
Hypothalamus2.38 ± 0.61
Insula2.77 ± 0.89
Limbic Lobe3.37 ± 0.74
Mesencephalon3.42 ± 0.78
Myelencephalon3.24 ± 0.7
Occipital Lobe3.56 ± 0.75
Parietal Lobe3.24 ± 0.63
Pontine Tegmentum3.14 ± 0.75
Striatum3.2 ± 0.72
Subthalamus3.13 ± 0.6
Temporal Lobe3.17 ± 0.74
Thalamus3.11 ± 0.74
White Matter4.81 ± 0.07
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved