AutismKB 2.0

Annotation Detail for DNAJC6


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Basic Information Top
Gene Symbol:DNAJC6 ( DJC6,KIAA0473,MGC129914,MGC129915,MGC48436 )
Gene Full Name: DnaJ (Hsp40) homolog, subfamily C, member 6
Band: 1p31.3
Quick LinksEntrez ID:9829; OMIM: 608375; Uniprot ID:AUXI_HUMAN; ENSEMBL ID: ENSG00000116675; HGNC ID: 15469
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus33 / 56401258
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal279 / 336030783
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain256 / 1100989232
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine3 / 23447212
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph2 / 4427045
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve4 / 15768253
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta10 / 28082535
prostate0 / 1893450 
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204720_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts81.95
Adipocyte7.05
AdrenalCortex8.85
Adrenalgland7
Amygdala1963.3
Appendix8.5
AtrioventricularNode6.65
BDCA4+_DentriticCells6.8
Bonemarrow8.35
BronchialEpithelialCells6.65
CD105+_Endothelial248.05
CD14+_Monocytes7.75
CD19+_BCells(neg._sel.)7
CD33+_Myeloid8.7
CD34+86.45
CD4+_Tcells6.9
CD56+_NKCells8.3
CD71+_EarlyErythroid201.55
CD8+_Tcells6.05
CardiacMyocytes10.3
Caudatenucleus452.5
Cerebellum320.05
CerebellumPeduncles281.7
CiliaryGanglion6.8
CingulateCortex551
Colorectaladenocarcinoma7.3
DorsalRootGanglion8.15
FetalThyroid7.05
Fetalbrain995.35
Fetalliver36.4
Fetallung5.4
GlobusPallidus362.7
Heart10.1
Hypothalamus1374.15
Kidney6.6
Leukemia_chronicMyelogenousK-56241.85
Leukemia_promyelocytic-HL-609.6
Leukemialymphoblastic(MOLT-4)5.65
Liver9.55
Lung7.45
Lymphnode5.9
Lymphoma_burkitts(Daudi)9.2
Lymphoma_burkitts(Raji)11.25
MedullaOblongata789.65
OccipitalLobe1286.1
OlfactoryBulb13.45
Ovary5.35
Pancreas6
PancreaticIslet7.85
ParietalLobe697.8
Pituitary202.2
Placenta25.85
Pons338.8
PrefrontalCortex1404.25
Prostate7.7
Salivarygland5.9
SkeletalMuscle10.2
Skin6.4
SmoothMuscle7.7
Spinalcord644.3
SubthalamicNucleus423
SuperiorCervicalGanglion10.35
TemporalLobe461.6
Testis6.1
TestisGermCell5.55
TestisIntersitial6.05
TestisLeydigCell7.2
TestisSeminiferousTubule5.9
Thalamus1129.2
Thymus5.25
Thyroid8.25
Tongue8.4
Tonsil7.05
Trachea5.75
TrigeminalGanglion8.3
Uterus5.75
UterusCorpus7.85
WholeBlood7.4
Wholebrain1336.7
colon7
pineal_day478.42
pineal_night473.08
retina150.85
small_intestine6.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P95359
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.37 ± 0.53
Basal Forebrain10.33 ± 0.21
Basal Part of Pons11.11 ± 0.15
Cerebellar Cortex10.37 ± 0.3
Cerebellar Nuclei10.86 ± 0.24
Claustrum10.87 ± 0.24
Epithalamus9.85 ± 0.76
Frontal Lobe10.71 ± 0.39
Globus Pallidus10.22 ± 0.65
Hypothalamus10.89 ± 0.28
Insula10.7 ± 0.21
Limbic Lobe10.75 ± 0.57
Mesencephalon10.67 ± 0.58
Myelencephalon10.56 ± 0.59
Occipital Lobe10.33 ± 0.61
Parietal Lobe10.78 ± 0.44
Pontine Tegmentum10.57 ± 0.39
Striatum9.78 ± 0.57
Subthalamus10.97 ± 0.46
Temporal Lobe10.83 ± 0.32
Thalamus10.57 ± 0.35
White Matter11.52 ± 0.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dnajc6CBCerebellum91.43
100
Dnajc6CTXCerebral cortex100
100
Dnajc6HIPHippocampal region100
100
Dnajc6HPFHippocampal formation100
100
Dnajc6HYHypothalamus100
100
Dnajc6LSXLateral septal complex100
100
Dnajc6MBMidbrain100
100
Dnajc6MYMedulla100
100
Dnajc6OLFOlfactory bulb100
100
Dnajc6PPons100
100
Dnajc6PALPallidum100
100
Dnajc6RHPRetrohippocampal region100
100
Dnajc6sAMYStriatum-like amygdalar nuclei100
100
Dnajc6STRStriatum88.18
87.87
Dnajc6STRdStriatum dorsal region78.34
75.68
Dnajc6STRvStriatum ventral region86.96
77.03
Dnajc6THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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