AutismKB 2.0

Annotation Detail for TRIM66


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Basic Information Top
Gene Symbol:TRIM66 ( C11orf29,FLJ10046,TIF1D,TIF1DELTA )
Gene Full Name: tripartite motif-containing 66
Band: 11p15.4
Quick LinksEntrez ID:9866; OMIM: 612000; Uniprot ID:TRI66_HUMAN; ENSEMBL ID: ENSG00000166436; HGNC ID: 29005
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor7 / 26384526
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal66 / 336030719
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood6 / 12347848
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine3 / 23447212
kidney7 / 21177733
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node7 / 9161076
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas4 / 21481218
parathyroid2 / 2053997
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta1 / 2808253
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis13 / 33044239
thymus0 / 811310 
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213748_at
Cell line Expression level Expression bar
721_B_lymphoblasts5
Adipocyte3.8
AdrenalCortex4
Adrenalgland3.2
Amygdala4.05
Appendix4.45
AtrioventricularNode3.05
BDCA4+_DentriticCells4.5
Bonemarrow3.75
BronchialEpithelialCells3.75
CD105+_Endothelial3.9
CD14+_Monocytes4.15
CD19+_BCells(neg._sel.)4.15
CD33+_Myeloid5.05
CD34+5
CD4+_Tcells5.1
CD56+_NKCells4.7
CD71+_EarlyErythroid3.55
CD8+_Tcells5
CardiacMyocytes4.65
Caudatenucleus3.4
Cerebellum3.1
CerebellumPeduncles4.3
CiliaryGanglion2.7
CingulateCortex3.9
Colorectaladenocarcinoma3.85
DorsalRootGanglion2.95
FetalThyroid3.75
Fetalbrain3.85
Fetalliver3.3
Fetallung3.2
GlobusPallidus2.8
Heart4.8
Hypothalamus4.25
Kidney3.1
Leukemia_chronicMyelogenousK-5623.45
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.1
Liver5.05
Lung4.25
Lymphnode3.3
Lymphoma_burkitts(Daudi)4.9
Lymphoma_burkitts(Raji)5.35
MedullaOblongata3.5
OccipitalLobe3.4
OlfactoryBulb3
Ovary2.55
Pancreas3.05
PancreaticIslet4.05
ParietalLobe4.05
Pituitary4.45
Placenta3.95
Pons3.6
PrefrontalCortex4.8
Prostate4.55
Salivarygland3.5
SkeletalMuscle4.4
Skin2.9
SmoothMuscle4.35
Spinalcord4.05
SubthalamicNucleus3.5
SuperiorCervicalGanglion4.25
TemporalLobe3.5
Testis3.5
TestisGermCell3.25
TestisIntersitial4.6
TestisLeydigCell3.75
TestisSeminiferousTubule3.3
Thalamus3.9
Thymus3.1
Thyroid4.8
Tongue3.7
Tonsil3.75
Trachea3.2
TrigeminalGanglion3.85
Uterus3.15
UterusCorpus3.4
WholeBlood4.2
Wholebrain3.3
colon3.8
pineal_day4.82
pineal_night4.72
retina4.675
small_intestine3.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P396186
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.82 ± 0.66
Basal Forebrain5.19 ± 0.44
Basal Part of Pons4.9 ± 0.5
Cerebellar Cortex5.26 ± 0.37
Cerebellar Nuclei4.88 ± 0.55
Claustrum4.87 ± 0.61
Epithalamus5.31 ± 0.59
Frontal Lobe4.94 ± 0.49
Globus Pallidus4.62 ± 0.65
Hypothalamus5.19 ± 0.55
Insula5.06 ± 0.48
Limbic Lobe4.62 ± 0.59
Mesencephalon5.09 ± 0.61
Myelencephalon4.94 ± 0.53
Occipital Lobe4.96 ± 0.44
Parietal Lobe5.03 ± 0.52
Pontine Tegmentum4.96 ± 0.5
Striatum5.06 ± 0.54
Subthalamus4.75 ± 0.54
Temporal Lobe4.76 ± 0.55
Thalamus5.14 ± 0.42
White Matter4.41 ± 0.44
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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