AutismKB 2.0

Annotation Detail for TOMM70A


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Basic Information Top
Gene Symbol:TOMM70A ( FLJ90470 )
Gene Full Name: translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
Band: 3q12.2
Quick LinksEntrez ID:9868; OMIM: 606081; Uniprot ID:TOM70_HUMAN; ENSEMBL ID: ENSG00000154174; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst6 / 6231996
fetus46 / 56401281
neonate0 / 310970 
infant3 / 23620127
juvenile3 / 5555653
adult128 / 193912166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor13 / 94178138
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor13 / 114246113
esophageal tumor4 / 17290231
gastrointestinal tumor6 / 11936950
germ cell tumor25 / 26384594
glioma4 / 10688337
head and neck tumor7 / 13630251
kidney tumor7 / 68959101
leukemia6 / 9584262
liver tumor12 / 96359124
lung tumor3 / 10312729
lymphoma3 / 7175541
non-neoplasia9 / 9725092
normal212 / 336030763
ovarian tumor8 / 76682104
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer7 / 10268068
retinoblastoma4 / 4635686
skin tumor18 / 124949144
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites2 / 4001549
bladder4 / 29757134
blood5 / 12347840
bone7 / 7165597
bone marrow4 / 4880181
brain64 / 110098958
cervix4 / 4817183
connective tissue5 / 14925533
ear1 / 1621261
embryonic tissue17 / 21572278
esophagus4 / 20209197
eye15 / 21105471
heart4 / 8962644
intestine21 / 23447289
kidney21 / 21177799
larynx1 / 2414541
liver23 / 207743110
lung12 / 33697435
lymph3 / 4427067
lymph node6 / 9161065
mammary gland19 / 153271123
mouth4 / 6705259
muscle6 / 10771555
nerve0 / 157680 
ovary10 / 10205197
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland3 / 16585180
placenta15 / 28082553
prostate17 / 18934589
salivary gland0 / 201550 
skin21 / 21057499
spleen0 / 539520 
stomach4 / 9661941
testis16 / 33044248
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus20 / 23287885
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201519_at
Cell line Expression level Expression bar
721_B_lymphoblasts688.5
Adipocyte127.15
AdrenalCortex106.2
Adrenalgland96.4
Amygdala389.7
Appendix138.15
AtrioventricularNode56.8
BDCA4+_DentriticCells255.6
Bonemarrow44.25
BronchialEpithelialCells195.75
CD105+_Endothelial396.55
CD14+_Monocytes148.7
CD19+_BCells(neg._sel.)227.55
CD33+_Myeloid143.85
CD34+492.55
CD4+_Tcells274.15
CD56+_NKCells312.45
CD71+_EarlyErythroid135.45
CD8+_Tcells236.2
CardiacMyocytes108
Caudatenucleus943.75
Cerebellum133.6
CerebellumPeduncles219.3
CiliaryGanglion64
CingulateCortex245.5
Colorectaladenocarcinoma85.35
DorsalRootGanglion63.8
FetalThyroid194.45
Fetalbrain469.5
Fetalliver168.6
Fetallung145
GlobusPallidus164.5
Heart29.85
Hypothalamus414.5
Kidney85.85
Leukemia_chronicMyelogenousK-562168.3
Leukemia_promyelocytic-HL-60349.25
Leukemialymphoblastic(MOLT-4)204.75
Liver65.5
Lung50.1
Lymphnode109.75
Lymphoma_burkitts(Daudi)205.3
Lymphoma_burkitts(Raji)174.35
MedullaOblongata304.35
OccipitalLobe244.05
OlfactoryBulb89.4
Ovary62.7
Pancreas147.4
PancreaticIslet181.8
ParietalLobe192.4
Pituitary235.3
Placenta100.75
Pons240.4
PrefrontalCortex657.55
Prostate169.4
Salivarygland80.6
SkeletalMuscle128.7
Skin47.65
SmoothMuscle151.6
Spinalcord224.65
SubthalamicNucleus230.55
SuperiorCervicalGanglion98.4
TemporalLobe159.9
Testis60.3
TestisGermCell106.1
TestisIntersitial70.8
TestisLeydigCell96.65
TestisSeminiferousTubule93.15
Thalamus185.7
Thymus90.2
Thyroid291.55
Tongue128.9
Tonsil95.15
Trachea98.25
TrigeminalGanglion32.05
Uterus175.35
UterusCorpus69.95
WholeBlood128.3
Wholebrain316.25
colon330.8
pineal_day1107.56
pineal_night980.02
retina205.8
small_intestine278.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9802_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.33 ± 0.35
Basal Forebrain7.35 ± 0.41
Basal Part of Pons7.79 ± 0.26
Cerebellar Cortex7.01 ± 0.1
Cerebellar Nuclei7.28 ± 0.35
Claustrum7.36 ± 0.24
Epithalamus6.71 ± 0.46
Frontal Lobe7.22 ± 0.3
Globus Pallidus6.84 ± 0.32
Hypothalamus7.48 ± 0.33
Insula7.26 ± 0.22
Limbic Lobe7.42 ± 0.36
Mesencephalon7.24 ± 0.49
Myelencephalon7.2 ± 0.45
Occipital Lobe7.45 ± 0.35
Parietal Lobe7.25 ± 0.43
Pontine Tegmentum7.24 ± 0.41
Striatum8.51 ± 0.49
Subthalamus7.54 ± 0.23
Temporal Lobe7.18 ± 0.27
Thalamus7.04 ± 0.29
White Matter6.63 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tomm70aCBCerebellum13.84
13.3
Tomm70aCTXCerebral cortex48.13
33.66
Tomm70aHIPHippocampal region71.77
74.12
Tomm70aHPFHippocampal formation64.66
59.29
Tomm70aHYHypothalamus18.3
12.88
Tomm70aLSXLateral septal complex24.45
19.45
Tomm70aMBMidbrain11.87
10.37
Tomm70aMYMedulla18.75
23.61
Tomm70aOLFOlfactory bulb61.49
44.68
Tomm70aPPons20.88
22.21
Tomm70aPALPallidum27.7
27.44
Tomm70aRHPRetrohippocampal region54.98
41.08
Tomm70asAMYStriatum-like amygdalar nuclei37.05
28.46
Tomm70aSTRStriatum100
100
Tomm70aSTRdStriatum dorsal region100
100
Tomm70aSTRvStriatum ventral region100
100
Tomm70aTHThalamus9.21
6.76
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000703 24 90 113 ASPAPGSGHPEGPGAHLDMNSLDR Peptide Atlas
TOM70_HUMAN_0 0 0 0 ILLDQVEEAVADFDECIR PRIDE
TOM70_HUMAN_246 13 246 258 NREPLMPSPQFIK PRIDE
TOM70_HUMAN_259 17 259 275 SYFSSFTDDIISQPMLK PRIDE
TOM70_HUMAN_335 19 335 353 ATFYLLIGNANAAKPDLDK PRIDE
TOM70_HUMAN_411 18 411 428 ILLDQVEEAVADFDECIR PRIDE
TOM70_HUMAN_576 24 576 599 SEMEMAHLYSLCDAAHAQTEVAKK PRIDE
TOM70_HUMAN_90 24 90 113 ASPAPGSGHPEGPGAHLDMNSLDR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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