AutismKB 2.0

Annotation Detail for SEC24D


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Basic Information Top
Gene Symbol:SEC24D ( FLJ43974,KIAA0755 )
Gene Full Name: SEC24 family, member D (S. cerevisiae)
Band: 4q26
Quick LinksEntrez ID:9871; OMIM: 607186; Uniprot ID:SC24D_HUMAN; ENSEMBL ID: ENSG00000150961; HGNC ID: 10706
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst6 / 6231996
fetus27 / 56401247
neonate1 / 3109732
infant1 / 2362042
juvenile4 / 5555671
adult149 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma10 / 82823120
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor20 / 26384575
glioma5 / 10688346
head and neck tumor11 / 13630280
kidney tumor5 / 6895972
leukemia9 / 9584293
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia8 / 9725082
normal190 / 336030756
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor24 / 90257265
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites2 / 4001549
bladder2 / 2975767
blood4 / 12347832
bone6 / 7165583
bone marrow3 / 4880161
brain35 / 110098931
cervix1 / 4817120
connective tissue16 / 149255107
ear3 / 16212185
embryonic tissue19 / 21572288
esophagus0 / 202090 
eye8 / 21105437
heart6 / 8962666
intestine7 / 23447229
kidney15 / 21177770
larynx0 / 241450 
liver9 / 20774343
lung12 / 33697435
lymph1 / 4427022
lymph node7 / 9161076
mammary gland7 / 15327145
mouth5 / 6705274
muscle7 / 10771564
nerve1 / 1576863
ovary1 / 1020519
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta27 / 28082596
prostate12 / 18934563
salivary gland4 / 20155198
skin7 / 21057433
spleen0 / 539520 
stomach8 / 9661982
testis45 / 330442136
thymus0 / 811310 
thyroid6 / 47473126
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord1 / 1368073
uterus54 / 232878231
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202375_at
Cell line Expression level Expression bar
721_B_lymphoblasts39.2
Adipocyte14.2
AdrenalCortex20.15
Adrenalgland13.8
Amygdala13.75
Appendix22
AtrioventricularNode19.3
BDCA4+_DentriticCells56.75
Bonemarrow16.15
BronchialEpithelialCells42.6
CD105+_Endothelial12.65
CD14+_Monocytes16
CD19+_BCells(neg._sel.)14.2
CD33+_Myeloid61.95
CD34+28.05
CD4+_Tcells11.5
CD56+_NKCells29.5
CD71+_EarlyErythroid12.9
CD8+_Tcells10.4
CardiacMyocytes45.75
Caudatenucleus11.4
Cerebellum11.45
CerebellumPeduncles17.55
CiliaryGanglion13.9
CingulateCortex14.45
Colorectaladenocarcinoma14.1
DorsalRootGanglion12.8
FetalThyroid17.35
Fetalbrain12.25
Fetalliver15.4
Fetallung15.55
GlobusPallidus11.6
Heart22.8
Hypothalamus12.15
Kidney13.15
Leukemia_chronicMyelogenousK-56213.05
Leukemia_promyelocytic-HL-6012
Leukemialymphoblastic(MOLT-4)10.45
Liver32
Lung15.95
Lymphnode18.6
Lymphoma_burkitts(Daudi)19.2
Lymphoma_burkitts(Raji)23.6
MedullaOblongata12
OccipitalLobe12.15
OlfactoryBulb10.2
Ovary11.25
Pancreas12.5
PancreaticIslet105.5
ParietalLobe16.4
Pituitary24.45
Placenta116.4
Pons14.55
PrefrontalCortex15.75
Prostate65
Salivarygland12.75
SkeletalMuscle20.75
Skin17.2
SmoothMuscle243.3
Spinalcord14.5
SubthalamicNucleus14
SuperiorCervicalGanglion31.5
TemporalLobe13.8
Testis17.25
TestisGermCell10.35
TestisIntersitial17.6
TestisLeydigCell15.3
TestisSeminiferousTubule11.8
Thalamus14.5
Thymus10.9
Thyroid47.95
Tongue18.05
Tonsil14.15
Trachea15.05
TrigeminalGanglion19.85
Uterus64.35
UterusCorpus14.5
WholeBlood38.6
Wholebrain11.4
colon65.75
pineal_day14.64
pineal_night14.94
retina17.55
small_intestine224.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6971_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.33 ± 0.97
Basal Forebrain2.95 ± 0.39
Basal Part of Pons2.72 ± 0.57
Cerebellar Cortex3.45 ± 0.56
Cerebellar Nuclei3.24 ± 0.79
Claustrum3.46 ± 0.68
Epithalamus2.7 ± 0.68
Frontal Lobe3.11 ± 0.65
Globus Pallidus2.48 ± 0.62
Hypothalamus3.45 ± 0.57
Insula3.26 ± 0.44
Limbic Lobe3.04 ± 0.7
Mesencephalon3.31 ± 0.78
Myelencephalon3.04 ± 0.7
Occipital Lobe2.82 ± 0.8
Parietal Lobe3.07 ± 0.67
Pontine Tegmentum3.08 ± 0.78
Striatum2.04 ± 0.76
Subthalamus3.04 ± 0.67
Temporal Lobe3.31 ± 0.59
Thalamus2.97 ± 0.61
White Matter2.86 ± 0.97
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sec24dCBCerebellum6.2
7.8
Sec24dCTXCerebral cortex23.94
17.34
Sec24dHIPHippocampal region30.24
40.53
Sec24dHPFHippocampal formation31.92
35.9
Sec24dHYHypothalamus22.18
17.44
Sec24dLSXLateral septal complex3.9
3.52
Sec24dMBMidbrain9.29
8.88
Sec24dMYMedulla17.61
18.34
Sec24dOLFOlfactory bulb28.62
22.08
Sec24dPPons9.47
9.15
Sec24dPALPallidum16.98
13.47
Sec24dRHPRetrohippocampal region35.38
29.5
Sec24dsAMYStriatum-like amygdalar nuclei18.33
12.91
Sec24dSTRStriatum14.14
10.53
Sec24dSTRdStriatum dorsal region14.35
10.94
Sec24dSTRvStriatum ventral region14.28
9.62
Sec24dTHThalamus29.31
26.99
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005729 15 852 866 NCVLLSRPEISTDER Peptide Atlas
SC24D_HUMAN_661 10 661 670 YNNFQMHLDR PRIDE
SC24D_HUMAN_671 8 671 678 QQFLNDLR PRIDE
SC24D_HUMAN_685 8 685 692 IGFDAIMR PRIDE
SC24D_HUMAN_899 9 899 907 STMLPAAVR PRIDE
SC24D_HUMAN_994 8 994 1001 EQPEMVFR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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