AutismKB 2.0

Annotation Detail for FCHSD2


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Basic Information Top
Gene Symbol:FCHSD2 ( KIAA0769,NWK,SH3MD3 )
Gene Full Name: FCH and double SH3 domains 2
Band: 11q13.4
Quick LinksEntrez ID:9873; OMIM: NA; Uniprot ID:FCSD2_HUMAN; ENSEMBL ID: ENSG00000137478; HGNC ID: 29114
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult61 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor8 / 26384530
glioma2 / 10688318
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal104 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone3 / 7165541
bone marrow1 / 4880120
brain38 / 110098934
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine5 / 23447221
kidney11 / 21177751
larynx1 / 2414541
liver2 / 2077439
lung18 / 33697453
lymph0 / 442700 
lymph node17 / 91610185
mammary gland5 / 15327132
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta7 / 28082524
prostate8 / 18934542
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis14 / 33044242
thymus2 / 8113124
thyroid5 / 47473105
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P302038
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.27 ± 0.27
Basal Forebrain5.71 ± 0.21
Basal Part of Pons5.23 ± 0.41
Cerebellar Cortex5.32 ± 0.24
Cerebellar Nuclei5.32 ± 0.37
Claustrum5.56 ± 0.36
Epithalamus5.3 ± 0.4
Frontal Lobe5.2 ± 0.42
Globus Pallidus6.37 ± 0.28
Hypothalamus5.38 ± 0.6
Insula5.3 ± 0.35
Limbic Lobe5.15 ± 0.5
Mesencephalon5.5 ± 0.64
Myelencephalon5.31 ± 0.51
Occipital Lobe5.13 ± 0.51
Parietal Lobe5.31 ± 0.57
Pontine Tegmentum5.36 ± 0.44
Striatum5.62 ± 0.53
Subthalamus5.12 ± 0.25
Temporal Lobe5.28 ± 0.34
Thalamus5.52 ± 0.33
White Matter6.18 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fchsd2CBCerebellum8.44
8.53
Fchsd2CTXCerebral cortex2.2
2.11
Fchsd2HIPHippocampal region4.32
4.12
Fchsd2HPFHippocampal formation3.42
2.97
Fchsd2HYHypothalamus2.03
1.49
Fchsd2LSXLateral septal complex0.95
0.69
Fchsd2MBMidbrain6.41
5.81
Fchsd2MYMedulla12.14
12.43
Fchsd2OLFOlfactory bulb6.88
6.76
Fchsd2PPons8.41
8.89
Fchsd2PALPallidum2.82
2.17
Fchsd2RHPRetrohippocampal region1.9
1.38
Fchsd2sAMYStriatum-like amygdalar nuclei1.84
1.34
Fchsd2STRStriatum1.56
1.16
Fchsd2STRdStriatum dorsal region0.85
0.7
Fchsd2STRvStriatum ventral region3.91
2.56
Fchsd2THThalamus4.84
4.14
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018