AutismKB 2.0

Annotation Detail for ZC3H11A


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Basic Information Top
Gene Symbol:ZC3H11A ( DKFZp686D03108,DKFZp686F14109,DKFZp781G2455,KIAA0663,ZC3HDC11A )
Gene Full Name: zinc finger CCCH-type containing 11A
Band: 1q32.1
Quick LinksEntrez ID:9877; OMIM: 613513; Uniprot ID:ZC11A_HUMAN; ENSEMBL ID: ENSG00000058673; HGNC ID: 29093
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst10 / 62319160
fetus79 / 564012140
neonate2 / 3109764
infant0 / 236200 
juvenile5 / 5555689
adult306 / 1939121157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma2 / 17475114
breast (mammary gland) tumor11 / 94178116
cervical tumor4 / 34366116
chondrosarcoma15 / 82823181
colorectal tumor18 / 114246157
esophageal tumor1 / 1729057
gastrointestinal tumor14 / 119369117
germ cell tumor49 / 263845185
glioma7 / 10688365
head and neck tumor22 / 136302161
kidney tumor12 / 68959174
leukemia14 / 95842146
liver tumor10 / 96359103
lung tumor5 / 10312748
lymphoma6 / 7175583
non-neoplasia11 / 97250113
normal416 / 3360307123
ovarian tumor7 / 7668291
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor8 / 12494964
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor26 / 90257288
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland4 / 33197120
ascites2 / 4001549
bladder2 / 2975767
blood9 / 12347872
bone15 / 71655209
bone marrow5 / 48801102
brain102 / 110098992
cervix4 / 4817183
connective tissue15 / 149255100
ear1 / 1621261
embryonic tissue29 / 215722134
esophagus1 / 2020949
eye19 / 21105490
heart14 / 89626156
intestine29 / 234472123
kidney21 / 21177799
larynx5 / 24145207
liver34 / 207743163
lung22 / 33697465
lymph2 / 4427045
lymph node25 / 91610272
mammary gland33 / 153271215
mouth5 / 6705274
muscle11 / 107715102
nerve2 / 15768126
ovary10 / 10205197
pancreas18 / 21481283
parathyroid7 / 20539340
pharynx4 / 4132896
pituitary gland2 / 16585120
placenta39 / 280825138
prostate10 / 18934552
salivary gland0 / 201550 
skin24 / 210574113
spleen3 / 5395255
stomach11 / 96619113
testis67 / 330442202
thymus13 / 81131160
thyroid11 / 47473231
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus53 / 232878227
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205787_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.3
Adipocyte3.65
AdrenalCortex3.8
Adrenalgland3.55
Amygdala3.95
Appendix3.95
AtrioventricularNode2.85
BDCA4+_DentriticCells22.25
Bonemarrow4.3
BronchialEpithelialCells3.75
CD105+_Endothelial4.45
CD14+_Monocytes4.05
CD19+_BCells(neg._sel.)10.05
CD33+_Myeloid8.65
CD34+6.5
CD4+_Tcells7.3
CD56+_NKCells20.75
CD71+_EarlyErythroid4.05
CD8+_Tcells5.8
CardiacMyocytes4.95
Caudatenucleus3.3
Cerebellum3.35
CerebellumPeduncles4.15
CiliaryGanglion2.7
CingulateCortex3.8
Colorectaladenocarcinoma3.7
DorsalRootGanglion2.9
FetalThyroid3.7
Fetalbrain3.7
Fetalliver3.75
Fetallung3.3
GlobusPallidus2.65
Heart4.55
Hypothalamus4
Kidney3
Leukemia_chronicMyelogenousK-5623.35
Leukemia_promyelocytic-HL-603.25
Leukemialymphoblastic(MOLT-4)3.65
Liver4.9
Lung4.1
Lymphnode3.25
Lymphoma_burkitts(Daudi)4.8
Lymphoma_burkitts(Raji)5.1
MedullaOblongata3.4
OccipitalLobe3.2
OlfactoryBulb2.85
Ovary2.65
Pancreas2.95
PancreaticIslet3.95
ParietalLobe3.75
Pituitary4.7
Placenta3.85
Pons3.5
PrefrontalCortex4.65
Prostate4.5
Salivarygland2.95
SkeletalMuscle4.2
Skin2.85
SmoothMuscle5
Spinalcord3.8
SubthalamicNucleus3.3
SuperiorCervicalGanglion5.05
TemporalLobe3.3
Testis3.2
TestisGermCell3.1
TestisIntersitial3.25
TestisLeydigCell4.75
TestisSeminiferousTubule3.15
Thalamus3.65
Thymus4.5
Thyroid4.75
Tongue3.7
Tonsil4.2
Trachea3.55
TrigeminalGanglion3.6
Uterus3.35
UterusCorpus3.3
WholeBlood4.3
Wholebrain3.2
colon4.6
pineal_day4.46
pineal_night4.36
retina4.275
small_intestine3.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P255194
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.72 ± 0.27
Basal Forebrain9.9 ± 0.16
Basal Part of Pons9.87 ± 0.22
Cerebellar Cortex10.25 ± 0.13
Cerebellar Nuclei10.02 ± 0.11
Claustrum9.65 ± 0.27
Epithalamus10.11 ± 0.32
Frontal Lobe9.99 ± 0.22
Globus Pallidus10.05 ± 0.24
Hypothalamus9.88 ± 0.25
Insula10.02 ± 0.31
Limbic Lobe9.95 ± 0.23
Mesencephalon10.01 ± 0.27
Myelencephalon9.96 ± 0.26
Occipital Lobe10.03 ± 0.19
Parietal Lobe9.98 ± 0.27
Pontine Tegmentum10 ± 0.21
Striatum9.91 ± 0.29
Subthalamus9.99 ± 0.12
Temporal Lobe9.95 ± 0.2
Thalamus10 ± 0.2
White Matter10.75 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zc3h11aCBCerebellum41.39
49.55
Zc3h11aCTXCerebral cortex100
83.3
Zc3h11aHIPHippocampal region60.65
93.83
Zc3h11aHPFHippocampal formation71.44
87.72
Zc3h11aHYHypothalamus48.8
35.15
Zc3h11aLSXLateral septal complex61.3
41.28
Zc3h11aMBMidbrain39.71
32.64
Zc3h11aMYMedulla36.89
33.34
Zc3h11aOLFOlfactory bulb100
89.2
Zc3h11aPPons35.69
32.15
Zc3h11aPALPallidum45.58
35.05
Zc3h11aRHPRetrohippocampal region96.83
83.37
Zc3h11asAMYStriatum-like amygdalar nuclei89.9
63.76
Zc3h11aSTRStriatum87.19
61.21
Zc3h11aSTRdStriatum dorsal region82.64
57.48
Zc3h11aSTRvStriatum ventral region100
78.95
Zc3h11aTHThalamus77.97
67.75
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010185 24 583 606 GDVASCNTQVAEKPVLTAVPGITR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018