Annotation Detail for SMG7
Basic Information Top
| Gene Symbol: | SMG7 ( C1orf16,EST1C,FLJ23717,KIAA0250,SGA56M ) |
|---|---|
| Gene Full Name: | Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) |
| Band: | 1q25.3 |
| Quick Links | Entrez ID:9887; OMIM: 610964; Uniprot ID:SMG7_HUMAN; ENSEMBL ID: ENSG00000116698; HGNC ID: 16792 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.591463
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 6 / 62319 | 96 |  |
| fetus | 44 / 564012 | 78 | |
| neonate | 1 / 31097 | 32 | |
| infant | 4 / 23620 | 169 | |
| juvenile | 6 / 55556 | 107 | |
| adult | 156 / 1939121 | 80 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 10 / 34366 | 290 |  |
| chondrosarcoma | 9 / 82823 | 108 | |
| colorectal tumor | 6 / 114246 | 52 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 31 / 263845 | 117 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 13 / 136302 | 95 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 18 / 95842 | 187 | |
| liver tumor | 14 / 96359 | 145 | |
| lung tumor | 1 / 103127 | 9 |  |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 7 / 97250 | 71 | |
| normal | 246 / 3360307 | 73 | |
| ovarian tumor | 12 / 76682 | 156 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 7 / 125680 | 55 | |
| prostate cancer | 27 / 102680 | 262 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 7 / 124949 | 56 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 9 / 90257 | 99 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 4 / 29757 | 134 | |
| blood | 15 / 123478 | 121 | |
| bone | 9 / 71655 | 125 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 62 / 1100989 | 56 | |
| cervix | 10 / 48171 | 207 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 13 / 215722 | 60 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 12 / 211054 | 56 | |
| heart | 3 / 89626 | 33 | |
| intestine | 19 / 234472 | 81 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 2 / 24145 | 82 | |
| liver | 22 / 207743 | 105 | |
| lung | 16 / 336974 | 47 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 29 / 91610 | 316 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 5 / 67052 | 74 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 10 / 102051 | 97 | |
| pancreas | 12 / 214812 | 55 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 4 / 41328 | 96 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 24 / 280825 | 85 | |
| prostate | 27 / 189345 | 142 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 18 / 210574 | 85 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 1 / 96619 | 10 | |
| testis | 56 / 330442 | 169 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 9 / 47473 | 189 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 4 / 52413 | 76 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 17 / 232878 | 72 | |
| vascular | 3 / 51780 | 57 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 201793_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 7.5 | |
| Adipocyte | 5.75 | |
| AdrenalCortex | 6 | |
| Adrenalgland | 5.1 | |
| Amygdala | 6.2 | |
| Appendix | 6.3 | |
| AtrioventricularNode | 4.55 | |
| BDCA4+_DentriticCells | 7.3 | |
| Bonemarrow | 5.85 | |
| BronchialEpithelialCells | 5.75 | |
| CD105+_Endothelial | 5.8 | |
| CD14+_Monocytes | 6.15 | |
| CD19+_BCells(neg._sel.) | 5.95 | |
| CD33+_Myeloid | 7.2 | |
| CD34+ | 6.85 | |
| CD4+_Tcells | 6.25 | |
| CD56+_NKCells | 6.65 | |
| CD71+_EarlyErythroid | 5.6 | |
| CD8+_Tcells | 5.45 | |
| CardiacMyocytes | 7.6 | |
| Caudatenucleus | 5.25 | |
| Cerebellum | 4.75 | |
| CerebellumPeduncles | 6.65 | |
| CiliaryGanglion | 4.1 | |
| CingulateCortex | 6 | |
| Colorectaladenocarcinoma | 5.9 | |
| DorsalRootGanglion | 4.5 | |
| FetalThyroid | 5.7 | |
| Fetalbrain | 5.85 | |
| Fetalliver | 5.05 | |
| Fetallung | 4.9 | |
| GlobusPallidus | 4.3 | |
| Heart | 7.55 | |
| Hypothalamus | 6.3 | |
| Kidney | 5.05 | |
| Leukemia_chronicMyelogenousK-562 | 5.3 | |
| Leukemia_promyelocytic-HL-60 | 5.1 | |
| Leukemialymphoblastic(MOLT-4) | 4.7 | |
| Liver | 8.05 | |
| Lung | 6.5 | |
| Lymphnode | 5.05 | |
| Lymphoma_burkitts(Daudi) | 7.4 | |
| Lymphoma_burkitts(Raji) | 8.2 | |
| MedullaOblongata | 5.4 | |
| OccipitalLobe | 5.3 | |
| OlfactoryBulb | 4.6 | |
| Ovary | 4 | |
| Pancreas | 4.65 | |
| PancreaticIslet | 6.25 | |
| ParietalLobe | 6.5 | |
| Pituitary | 7 | |
| Placenta | 5.95 | |
| Pons | 7.1 | |
| PrefrontalCortex | 6.85 | |
| Prostate | 6.85 | |
| Salivarygland | 4.7 | |
| SkeletalMuscle | 7.2 | |
| Skin | 4.5 | |
| SmoothMuscle | 6.65 | |
| Spinalcord | 6.2 | |
| SubthalamicNucleus | 5.35 | |
| SuperiorCervicalGanglion | 6.9 | |
| TemporalLobe | 5.5 | |
| Testis | 6.3 | |
| TestisGermCell | 4.85 | |
| TestisIntersitial | 5.1 | |
| TestisLeydigCell | 6.1 | |
| TestisSeminiferousTubule | 5.05 | |
| Thalamus | 5.95 | |
| Thymus | 4.7 | |
| Thyroid | 7.3 | |
| Tongue | 5.9 | |
| Tonsil | 5.65 | |
| Trachea | 4.9 | |
| TrigeminalGanglion | 6.35 | |
| Uterus | 4.75 | |
| UterusCorpus | 5.95 | |
| WholeBlood | 6.45 | |
| Wholebrain | 4.95 | |
| colon | 5.9 | |
| pineal_day | 7.26 | |
| pineal_night | 7.14 | |
| retina | 7 | |
| small_intestine | 5.65 | |
- Probe name: CUST_7321_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.13 ± 0.92 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.14 ± 0.33 | |
| Basal Part of Pons | 5.23 ± 0.49 | |
| Cerebellar Cortex | 5.49 ± 0.23 | |
| Cerebellar Nuclei | 4.91 ± 0.55 | |
| Claustrum | 4.55 ± 0.68 | |
| Epithalamus | 5.38 ± 0.42 | |
| Frontal Lobe | 5.09 ± 0.47 | |
| Globus Pallidus | 4.35 ± 0.51 | |
| Hypothalamus | 4.68 ± 0.44 | |
| Insula | 5.15 ± 0.42 | |
| Limbic Lobe | 5.2 ± 0.44 | |
| Mesencephalon | 5.06 ± 0.51 | |
| Myelencephalon | 5.09 ± 0.53 | |
| Occipital Lobe | 5.12 ± 0.41 | |
| Parietal Lobe | 5.23 ± 0.4 | |
| Pontine Tegmentum | 5.08 ± 0.4 | |
| Striatum | 4.8 ± 0.5 | |
| Subthalamus | 5.12 ± 0.2 | |
| Temporal Lobe | 5.29 ± 0.39 | |
| Thalamus | 5.03 ± 0.38 | |
| White Matter | 4.91 ± 0.46 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Smg7 | CB | Cerebellum | 57.28 | |
| 72.17 | | |||
| Smg7 | CTX | Cerebral cortex | 100 | |
| 77.26 | | |||
| Smg7 | HIP | Hippocampal region | 60.79 | |
| 78.68 | | |||
| Smg7 | HPF | Hippocampal formation | 69.45 | |
| 73.72 | | |||
| Smg7 | HY | Hypothalamus | 43.92 | |
| 32.07 | | |||
| Smg7 | LSX | Lateral septal complex | 59.5 | |
| 40.48 | | |||
| Smg7 | MB | Midbrain | 49.16 | |
| 41.36 | | |||
| Smg7 | MY | Medulla | 47.79 | |
| 49.06 | | |||
| Smg7 | OLF | Olfactory bulb | 84.69 | |
| 71.43 | | |||
| Smg7 | P | Pons | 43.9 | |
| 41.78 | | |||
| Smg7 | PAL | Pallidum | 32.43 | |
| 25.76 | | |||
| Smg7 | RHP | Retrohippocampal region | 83.28 | |
| 67.89 | | |||
| Smg7 | sAMY | Striatum-like amygdalar nuclei | 40.37 | |
| 26.95 | | |||
| Smg7 | STR | Striatum | 53.66 | |
| 35.74 | | |||
| Smg7 | STRd | Striatum dorsal region | 53.68 | |
| 35.74 | | |||
| Smg7 | STRv | Striatum ventral region | 60.72 | |
| 39.6 | | |||
| Smg7 | TH | Thalamus | 49.4 | |
| 39.15 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| SMG7_HUMAN_2 | 9 | 2 | 10 | SLQSAQYLR | PRIDE |