AutismKB 2.0

Annotation Detail for SV2B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SV2B ( FLJ30413,FLJ42732,HsT19680,KIAA0735 )
Gene Full Name: synaptic vesicle glycoprotein 2B
Band: 15q26.1
Quick LinksEntrez ID:9899; OMIM: 185861; Uniprot ID:SV2B_HUMAN; ENSEMBL ID: ENSG00000185518; HGNC ID: 16874
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant2 / 2362084
juvenile3 / 5555653
adult83 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal192 / 336030757
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma6 / 46356129
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain115 / 1100989104
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye39 / 211054184
heart1 / 8962611
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve3 / 15768190
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205551_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.35
Adipocyte6.55
AdrenalCortex7.85
Adrenalgland6
Amygdala727
Appendix7.6
AtrioventricularNode5.15
BDCA4+_DentriticCells7.65
Bonemarrow6.7
BronchialEpithelialCells6.35
CD105+_Endothelial6.85
CD14+_Monocytes7.05
CD19+_BCells(neg._sel.)7.2
CD33+_Myeloid8.75
CD34+8.65
CD4+_Tcells7.5
CD56+_NKCells7.9
CD71+_EarlyErythroid6.45
CD8+_Tcells6.45
CardiacMyocytes8.45
Caudatenucleus31.1
Cerebellum381.8
CerebellumPeduncles564.65
CiliaryGanglion5.35
CingulateCortex575.6
Colorectaladenocarcinoma6.45
DorsalRootGanglion16.4
FetalThyroid6.65
Fetalbrain47.3
Fetalliver5.8
Fetallung5.75
GlobusPallidus282.65
Heart8.6
Hypothalamus106.45
Kidney5.5
Leukemia_chronicMyelogenousK-5626.2
Leukemia_promyelocytic-HL-606.1
Leukemialymphoblastic(MOLT-4)5.55
Liver8.8
Lung9.65
Lymphnode6
Lymphoma_burkitts(Daudi)8.65
Lymphoma_burkitts(Raji)9.4
MedullaOblongata380.45
OccipitalLobe602
OlfactoryBulb9.9
Ovary5.7
Pancreas5.4
PancreaticIslet11.45
ParietalLobe520.3
Pituitary26.1
Placenta8.8
Pons133.4
PrefrontalCortex983.2
Prostate8.95
Salivarygland5.75
SkeletalMuscle7.65
Skin5.15
SmoothMuscle7.85
Spinalcord16.45
SubthalamicNucleus505.7
SuperiorCervicalGanglion16.65
TemporalLobe522.45
Testis5.9
TestisGermCell5.85
TestisIntersitial8.15
TestisLeydigCell6.75
TestisSeminiferousTubule5.9
Thalamus269.05
Thymus5.65
Thyroid8.65
Tongue6.55
Tonsil6.65
Trachea5.65
TrigeminalGanglion6.7
Uterus5.65
UterusCorpus6.1
WholeBlood7.5
Wholebrain567.7
colon7.25
pineal_day903.08
pineal_night848.5
retina331.9
small_intestine6.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10956_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.59 ± 1.09
Basal Forebrain6.12 ± 0.99
Basal Part of Pons8.6 ± 0.26
Cerebellar Cortex7.88 ± 0.15
Cerebellar Nuclei7.43 ± 0.56
Claustrum7.92 ± 0.41
Epithalamus6.07 ± 0.79
Frontal Lobe7.68 ± 0.44
Globus Pallidus5.07 ± 0.7
Hypothalamus6.6 ± 0.85
Insula7.62 ± 0.51
Limbic Lobe7.86 ± 0.6
Mesencephalon6.81 ± 0.86
Myelencephalon7.36 ± 0.97
Occipital Lobe6.71 ± 1.03
Parietal Lobe7.55 ± 0.67
Pontine Tegmentum7.12 ± 0.72
Striatum5.67 ± 1.03
Subthalamus7.52 ± 0.66
Temporal Lobe7.8 ± 0.45
Thalamus7.16 ± 0.56
White Matter5.45 ± 0.86
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sv2bCBCerebellum52.99
77.73
Sv2bCTXCerebral cortex100
100
Sv2bHIPHippocampal region95.44
100
Sv2bHPFHippocampal formation100
100
Sv2bHYHypothalamus16.54
16.08
Sv2bLSXLateral septal complex31.7
40.39
Sv2bMBMidbrain29.17
36.17
Sv2bMYMedulla41.18
75.01
Sv2bOLFOlfactory bulb100
100
Sv2bPPons37.26
67.92
Sv2bPALPallidum16.58
15.89
Sv2bRHPRetrohippocampal region100
100
Sv2bsAMYStriatum-like amygdalar nuclei43.78
46.57
Sv2bSTRStriatum57.17
52.64
Sv2bSTRdStriatum dorsal region62.98
57.96
Sv2bSTRvStriatum ventral region54.68
42.01
Sv2bTHThalamus83.8
91.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved