AutismKB 2.0

Annotation Detail for ARNT2


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Basic Information Top
Gene Symbol:ARNT2 ( KIAA0307,bHLHe1 )
Gene Full Name: aryl-hydrocarbon receptor nuclear translocator 2
Band: 15q25.1
Quick LinksEntrez ID:9915; OMIM: 606036; Uniprot ID:ARNT2_HUMAN; ENSEMBL ID: ENSG00000172379; HGNC ID: 16876
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus39 / 56401269
neonate0 / 310970 
infant7 / 23620296
juvenile4 / 5555671
adult83 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor8 / 26384530
glioma13 / 106883121
head and neck tumor6 / 13630244
kidney tumor7 / 68959101
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal250 / 336030774
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain196 / 1100989178
cervix6 / 48171124
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye15 / 21105471
heart2 / 8962622
intestine4 / 23447217
kidney18 / 21177784
larynx0 / 241450 
liver1 / 2077434
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth4 / 6705259
muscle3 / 10771527
nerve4 / 15768253
ovary1 / 1020519
pancreas4 / 21481218
parathyroid6 / 20539292
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta2 / 2808257
prostate3 / 18934515
salivary gland0 / 201550 
skin8 / 21057437
spleen1 / 5395218
stomach11 / 96619113
testis15 / 33044245
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202986_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.65
Adipocyte8.25
AdrenalCortex10.7
Adrenalgland7.5
Amygdala741.55
Appendix15.55
AtrioventricularNode8.65
BDCA4+_DentriticCells8.8
Bonemarrow9
BronchialEpithelialCells7.45
CD105+_Endothelial7.7
CD14+_Monocytes8.9
CD19+_BCells(neg._sel.)8.45
CD33+_Myeloid10.1
CD34+9.3
CD4+_Tcells9.05
CD56+_NKCells8.45
CD71+_EarlyErythroid7.95
CD8+_Tcells7.55
CardiacMyocytes11.7
Caudatenucleus556.3
Cerebellum56.4
CerebellumPeduncles113.45
CiliaryGanglion14.05
CingulateCortex568.15
Colorectaladenocarcinoma8.95
DorsalRootGanglion14.9
FetalThyroid17.45
Fetalbrain266.55
Fetalliver7.95
Fetallung7.1
GlobusPallidus269.45
Heart11.7
Hypothalamus448.1
Kidney29.1
Leukemia_chronicMyelogenousK-5627.85
Leukemia_promyelocytic-HL-607.75
Leukemialymphoblastic(MOLT-4)6.35
Liver12.55
Lung9.75
Lymphnode7.85
Lymphoma_burkitts(Daudi)11.45
Lymphoma_burkitts(Raji)12.75
MedullaOblongata542.85
OccipitalLobe451.1
OlfactoryBulb59
Ovary7.55
Pancreas7.05
PancreaticIslet12.45
ParietalLobe369.2
Pituitary25.3
Placenta8.8
Pons359.3
PrefrontalCortex1147.4
Prostate10.15
Salivarygland7.3
SkeletalMuscle11.75
Skin7.25
SmoothMuscle9.4
Spinalcord235.15
SubthalamicNucleus550.45
SuperiorCervicalGanglion31.05
TemporalLobe467.7
Testis15.6
TestisGermCell13.75
TestisIntersitial9.4
TestisLeydigCell9.35
TestisSeminiferousTubule19.05
Thalamus251.3
Thymus5.9
Thyroid10.45
Tongue9.5
Tonsil8.85
Trachea7.45
TrigeminalGanglion32.45
Uterus6.7
UterusCorpus8.05
WholeBlood8.6
Wholebrain616.15
colon8
pineal_day78.3
pineal_night103.52
retina135.325
small_intestine7.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7028_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.39 ± 0.48
Basal Forebrain6.62 ± 0.19
Basal Part of Pons6.1 ± 0.33
Cerebellar Cortex6.16 ± 0.36
Cerebellar Nuclei6.39 ± 0.39
Claustrum7.15 ± 0.61
Epithalamus6.61 ± 0.71
Frontal Lobe6.58 ± 0.52
Globus Pallidus6.82 ± 0.35
Hypothalamus6.24 ± 0.55
Insula6.76 ± 0.42
Limbic Lobe7.2 ± 0.44
Mesencephalon6.84 ± 0.47
Myelencephalon6.74 ± 0.62
Occipital Lobe7.2 ± 0.51
Parietal Lobe6.85 ± 0.56
Pontine Tegmentum6.92 ± 0.35
Striatum7.42 ± 0.29
Subthalamus6.52 ± 0.3
Temporal Lobe6.76 ± 0.46
Thalamus6.37 ± 0.47
White Matter6.18 ± 0.76
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Arnt2CBCerebellum12.87
14.45
Arnt2CTXCerebral cortex100
100
Arnt2HIPHippocampal region38.36
55.98
Arnt2HPFHippocampal formation54.56
67.92
Arnt2HYHypothalamus54.76
50.53
Arnt2LSXLateral septal complex41.86
42.48
Arnt2MBMidbrain43.92
41.59
Arnt2MYMedulla40.12
41.55
Arnt2OLFOlfactory bulb68.99
66.58
Arnt2PPons38.82
38.97
Arnt2PALPallidum50.56
54.11
Arnt2RHPRetrohippocampal region96.85
97.86
Arnt2sAMYStriatum-like amygdalar nuclei58.55
51.6
Arnt2STRStriatum40.55
33.31
Arnt2STRdStriatum dorsal region31.45
25.13
Arnt2STRvStriatum ventral region55.24
39.99
Arnt2THThalamus17.99
18.07
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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