AutismKB 2.0

Annotation Detail for FAM20B


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Basic Information Top
Gene Symbol:FAM20B ( gxk1 )
Gene Full Name: family with sequence similarity 20, member B
Band: 1q25.2
Quick LinksEntrez ID:9917; OMIM: 611063; Uniprot ID:XYLK_HUMAN; ENSEMBL ID: ENSG00000116199; HGNC ID: 23017
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal58 / 336030717
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain4 / 11009893
cervix1 / 4817120
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye5 / 21105423
heart6 / 8962666
intestine4 / 23447217
kidney3 / 21177714
larynx1 / 2414541
liver5 / 20774324
lung9 / 33697426
lymph0 / 442700 
lymph node7 / 9161076
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate4 / 18934521
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202915_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts26.75
Adipocyte28
AdrenalCortex20.45
Adrenalgland14
Amygdala64.3
Appendix17.6
AtrioventricularNode16.9
BDCA4+_DentriticCells30.95
Bonemarrow19.7
BronchialEpithelialCells21.8
CD105+_Endothelial23.05
CD14+_Monocytes20.5
CD19+_BCells(neg._sel.)38.65
CD33+_Myeloid27.65
CD34+29.05
CD4+_Tcells20.95
CD56+_NKCells23.8
CD71+_EarlyErythroid159
CD8+_Tcells23.75
CardiacMyocytes25.35
Caudatenucleus18.85
Cerebellum15.3
CerebellumPeduncles22.5
CiliaryGanglion18.45
CingulateCortex19.7
Colorectaladenocarcinoma19.3
DorsalRootGanglion15.65
FetalThyroid16.65
Fetalbrain20.05
Fetalliver19.75
Fetallung17.25
GlobusPallidus19.5
Heart23.3
Hypothalamus24.85
Kidney13
Leukemia_chronicMyelogenousK-56265.1
Leukemia_promyelocytic-HL-6016.9
Leukemialymphoblastic(MOLT-4)12.2
Liver20.95
Lung17.9
Lymphnode14.55
Lymphoma_burkitts(Daudi)24.1
Lymphoma_burkitts(Raji)27.1
MedullaOblongata16.9
OccipitalLobe17.25
OlfactoryBulb16.1
Ovary11.6
Pancreas15.2
PancreaticIslet22.3
ParietalLobe22.65
Pituitary30.35
Placenta16.7
Pons18.25
PrefrontalCortex27.05
Prostate28.9
Salivarygland13.2
SkeletalMuscle22.85
Skin14
SmoothMuscle21.8
Spinalcord18.8
SubthalamicNucleus25.8
SuperiorCervicalGanglion29.5
TemporalLobe17.5
Testis12.45
TestisGermCell13.85
TestisIntersitial14.35
TestisLeydigCell17.9
TestisSeminiferousTubule13.8
Thalamus22.3
Thymus10.8
Thyroid45.15
Tongue18.45
Tonsil16.85
Trachea15.2
TrigeminalGanglion21.55
Uterus30.4
UterusCorpus19.6
WholeBlood19.1
Wholebrain16.45
colon19.45
pineal_day206
pineal_night261.66
retina23.45
small_intestine22.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P160649
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.97 ± 0.27
Basal Forebrain4.82 ± 0.25
Basal Part of Pons4.98 ± 0.45
Cerebellar Cortex4.76 ± 0.41
Cerebellar Nuclei4.74 ± 0.38
Claustrum4.92 ± 0.77
Epithalamus4.46 ± 0.32
Frontal Lobe4.88 ± 0.42
Globus Pallidus4.42 ± 0.61
Hypothalamus4.54 ± 0.52
Insula4.89 ± 0.38
Limbic Lobe4.87 ± 0.42
Mesencephalon4.64 ± 0.57
Myelencephalon4.68 ± 0.48
Occipital Lobe4.46 ± 0.49
Parietal Lobe4.8 ± 0.48
Pontine Tegmentum4.79 ± 0.51
Striatum4.25 ± 0.53
Subthalamus5.03 ± 0.26
Temporal Lobe4.85 ± 0.37
Thalamus4.6 ± 0.51
White Matter4.55 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
C530043G21RikCBCerebellum3.67
5.92
C530043G21RikCTXCerebral cortex48.23
43.22
C530043G21RikHIPHippocampal region42.52
77.21
C530043G21RikHPFHippocampal formation40.04
58.32
C530043G21RikHYHypothalamus55.57
52.82
C530043G21RikLSXLateral septal complex33.48
28.92
C530043G21RikMBMidbrain23.22
26.21
C530043G21RikMYMedulla3.57
6.65
C530043G21RikOLFOlfactory bulb24.41
26.72
C530043G21RikPPons8.95
12.75
C530043G21RikPALPallidum48.67
54.67
C530043G21RikRHPRetrohippocampal region36.67
34.66
C530043G21RiksAMYStriatum-like amygdalar nuclei69.14
60.33
C530043G21RikSTRStriatum20.92
18.66
C530043G21RikSTRdStriatum dorsal region14.94
13.29
C530043G21RikSTRvStriatum ventral region15.79
15.04
C530043G21RikTHThalamus44.19
43.5
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003462 12 144 155 HNAEVAAFHLDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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