Annotation Detail for SEC16A
Basic Information Top
| Gene Symbol: | SEC16A ( FLJ26737,KIAA0310,RP11-413M3.10,SEC16L,p250 ) |
|---|---|
| Gene Full Name: | SEC16 homolog A (S. cerevisiae) |
| Band: | 9q34.3 |
| Quick Links | Entrez ID:9919; OMIM: 612854; Uniprot ID:SC16A_HUMAN; ENSEMBL ID: ENSG00000148396; HGNC ID: 29006 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.668588
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 5 / 70761 | 70 |  |
| blastocyst | 7 / 62319 | 112 | |
| fetus | 75 / 564012 | 132 | |
| neonate | 1 / 31097 | 32 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 4 / 55556 | 71 | |
| adult | 226 / 1939121 | 116 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 0 / 564012 | 0 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 0 / 1939121 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 13 / 94178 | 138 | |
| cervical tumor | 4 / 34366 | 116 | |
| chondrosarcoma | 13 / 82823 | 156 | |
| colorectal tumor | 23 / 114246 | 201 |  |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 23 / 119369 | 192 | |
| germ cell tumor | 45 / 263845 | 170 | |
| glioma | 13 / 106883 | 121 | |
| head and neck tumor | 16 / 136302 | 117 | |
| kidney tumor | 10 / 68959 | 145 | |
| leukemia | 28 / 95842 | 292 | |
| liver tumor | 9 / 96359 | 93 | |
| lung tumor | 16 / 103127 | 155 | |
| lymphoma | 4 / 71755 | 55 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 311 / 3360307 | 92 | |
| ovarian tumor | 11 / 76682 | 143 | |
| pancreatic tumor | 30 / 104616 | 286 | |
| primitive neuroectodermal tumor of the CNS | 5 / 125680 | 39 | |
| prostate cancer | 3 / 102680 | 29 | |
| retinoblastoma | 6 / 46356 | 129 | |
| skin tumor | 5 / 124949 | 40 | |
| soft tissue/muscle tissue tumor | 6 / 125191 | 47 | |
| uterine tumor | 16 / 90257 | 177 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 1 / 96359 | 10 |  |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 6 / 3360307 | 1 |  |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 4 / 33197 | 120 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 12 / 123478 | 97 | |
| bone | 9 / 71655 | 125 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 73 / 1100989 | 66 | |
| cervix | 8 / 48171 | 166 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 22 / 215722 | 101 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 18 / 211054 | 85 | |
| heart | 19 / 89626 | 211 | |
| intestine | 30 / 234472 | 127 | |
| kidney | 26 / 211777 | 122 | |
| larynx | 5 / 24145 | 207 | |
| liver | 14 / 207743 | 67 | |
| lung | 41 / 336974 | 121 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 41 / 91610 | 447 | |
| mammary gland | 20 / 153271 | 130 | |
| mouth | 8 / 67052 | 119 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 3 / 15768 | 190 | |
| ovary | 11 / 102051 | 107 | |
| pancreas | 39 / 214812 | 181 | |
| parathyroid | 4 / 20539 | 194 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 21 / 280825 | 74 | |
| prostate | 17 / 189345 | 89 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 10 / 210574 | 47 | |
| spleen | 5 / 53952 | 92 | |
| stomach | 24 / 96619 | 248 | |
| testis | 31 / 330442 | 93 | |
| thymus | 7 / 81131 | 86 | |
| thyroid | 6 / 47473 | 126 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 7 / 52413 | 133 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 40 / 232878 | 171 | |
| vascular | 0 / 51780 | 0 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 5 / 1100989 | 4 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 215696_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 182.4 | |
| Adipocyte | 28.45 | |
| AdrenalCortex | 92.6 | |
| Adrenalgland | 117.1 | |
| Amygdala | 41.8 | |
| Appendix | 9.2 | |
| AtrioventricularNode | 19.75 | |
| BDCA4+_DentriticCells | 347.25 | |
| Bonemarrow | 135.45 | |
| BronchialEpithelialCells | 97.35 | |
| CD105+_Endothelial | 174.6 | |
| CD14+_Monocytes | 173.35 | |
| CD19+_BCells(neg._sel.) | 103 | |
| CD33+_Myeloid | 478.65 | |
| CD34+ | 370.95 | |
| CD4+_Tcells | 321.9 | |
| CD56+_NKCells | 331.7 | |
| CD71+_EarlyErythroid | 33.85 | |
| CD8+_Tcells | 340.65 | |
| CardiacMyocytes | 38.75 | |
| Caudatenucleus | 20.7 | |
| Cerebellum | 93.85 | |
| CerebellumPeduncles | 48.55 | |
| CiliaryGanglion | 15.75 | |
| CingulateCortex | 21.9 | |
| Colorectaladenocarcinoma | 188.2 | |
| DorsalRootGanglion | 19.8 | |
| FetalThyroid | 118.25 | |
| Fetalbrain | 56.65 | |
| Fetalliver | 67 | |
| Fetallung | 86.9 | |
| GlobusPallidus | 15.95 | |
| Heart | 46.35 | |
| Hypothalamus | 70.65 | |
| Kidney | 34.95 | |
| Leukemia_chronicMyelogenousK-562 | 118 | |
| Leukemia_promyelocytic-HL-60 | 21.45 | |
| Leukemialymphoblastic(MOLT-4) | 73.25 | |
| Liver | 349.65 | |
| Lung | 353.7 | |
| Lymphnode | 66.45 | |
| Lymphoma_burkitts(Daudi) | 62.7 | |
| Lymphoma_burkitts(Raji) | 52.15 | |
| MedullaOblongata | 34.1 | |
| OccipitalLobe | 49.3 | |
| OlfactoryBulb | 14.55 | |
| Ovary | 20.3 | |
| Pancreas | 67.35 | |
| PancreaticIslet | 96.5 | |
| ParietalLobe | 20.6 | |
| Pituitary | 126.7 | |
| Placenta | 172.9 | |
| Pons | 12.65 | |
| PrefrontalCortex | 175.05 | |
| Prostate | 585.65 | |
| Salivarygland | 52.3 | |
| SkeletalMuscle | 11.85 | |
| Skin | 16.25 | |
| SmoothMuscle | 186.65 | |
| Spinalcord | 57.8 | |
| SubthalamicNucleus | 40.7 | |
| SuperiorCervicalGanglion | 10.85 | |
| TemporalLobe | 17 | |
| Testis | 220.15 | |
| TestisGermCell | 80.55 | |
| TestisIntersitial | 49.65 | |
| TestisLeydigCell | 38.45 | |
| TestisSeminiferousTubule | 47.5 | |
| Thalamus | 31.25 | |
| Thymus | 249.45 | |
| Thyroid | 136 | |
| Tongue | 13.2 | |
| Tonsil | 49.55 | |
| Trachea | 107.3 | |
| TrigeminalGanglion | 16.4 | |
| Uterus | 66.8 | |
| UterusCorpus | 17.75 | |
| WholeBlood | 119.4 | |
| Wholebrain | 109.4 | |
| colon | 57.6 | |
| pineal_day | 113.54 | |
| pineal_night | 145.16 | |
| retina | 195.2 | |
| small_intestine | 63.85 | |
- Probe name: A_23_P251303
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.94 ± 0.47 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.14 ± 0.27 | |
| Basal Part of Pons | 6.43 ± 0.28 | |
| Cerebellar Cortex | 6.51 ± 0.3 | |
| Cerebellar Nuclei | 5.99 ± 0.43 | |
| Claustrum | 5.77 ± 0.53 | |
| Epithalamus | 6.36 ± 0.62 | |
| Frontal Lobe | 6.25 ± 0.45 | |
| Globus Pallidus | 5.54 ± 0.26 | |
| Hypothalamus | 6.17 ± 0.34 | |
| Insula | 6.36 ± 0.32 | |
| Limbic Lobe | 6.22 ± 0.44 | |
| Mesencephalon | 6.08 ± 0.46 | |
| Myelencephalon | 6.17 ± 0.45 | |
| Occipital Lobe | 6.39 ± 0.31 | |
| Parietal Lobe | 6.28 ± 0.38 | |
| Pontine Tegmentum | 6.17 ± 0.41 | |
| Striatum | 5.93 ± 0.38 | |
| Subthalamus | 6.15 ± 0.44 | |
| Temporal Lobe | 6.37 ± 0.35 | |
| Thalamus | 6.26 ± 0.36 | |
| White Matter | 5.82 ± 0.34 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| AU024582 | CB | Cerebellum | 24.59 | |
| 33.51 | | |||
| AU024582 | CTX | Cerebral cortex | 65.7 | |
| 49.96 | | |||
| AU024582 | HIP | Hippocampal region | 42 | |
| 50.52 | | |||
| AU024582 | HPF | Hippocampal formation | 55.72 | |
| 58.03 | | |||
| AU024582 | HY | Hypothalamus | 30.81 | |
| 23.68 | | |||
| AU024582 | LSX | Lateral septal complex | 20.87 | |
| 14.11 | | |||
| AU024582 | MB | Midbrain | 29.05 | |
| 25.53 | | |||
| AU024582 | MY | Medulla | 40.72 | |
| 41.31 | | |||
| AU024582 | OLF | Olfactory bulb | 56.79 | |
| 45.76 | | |||
| AU024582 | P | Pons | 35.62 | |
| 34.71 | | |||
| AU024582 | PAL | Pallidum | 44.4 | |
| 39.9 | | |||
| AU024582 | RHP | Retrohippocampal region | 87.29 | |
| 75.64 | | |||
| AU024582 | sAMY | Striatum-like amygdalar nuclei | 78.09 | |
| 61.04 | | |||
| AU024582 | STR | Striatum | 39.89 | |
| 29.34 | | |||
| AU024582 | STRd | Striatum dorsal region | 40.53 | |
| 30.23 | | |||
| AU024582 | STRv | Striatum ventral region | 29.14 | |
| 19.2 | | |||
| AU024582 | TH | Thalamus | 36.65 | |
| 33.19 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00040699 | 27 | 322 | 348 | HGAVCHTGAPDATLHTVHPDSVSSSYS | Peptide Atlas |
| SC16A_HUMAN_1272 | 12 | 1272 | 1283 | KAPPPPPTSMPK | PRIDE |
| SC16A_HUMAN_1369 | 16 | 1369 | 1384 | QNGTVVGTDIAELLLR | PRIDE |