AutismKB 2.0

Annotation Detail for DCLRE1A


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Basic Information Top
Gene Symbol:DCLRE1A ( KIAA0086,PSO2,SNM1,SNM1A )
Gene Full Name: DNA cross-link repair 1A
Band: 10q25.3
Quick LinksEntrez ID:9937; OMIM: 609682; Uniprot ID:DCR1A_HUMAN; ENSEMBL ID: ENSG00000198924; HGNC ID: 17660
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus18 / 56401231
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal59 / 336030717
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain15 / 110098913
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye6 / 21105428
heart3 / 8962633
intestine3 / 23447212
kidney1 / 2117774
larynx1 / 2414541
liver3 / 20774314
lung4 / 33697411
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth3 / 6705244
muscle3 / 10771527
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin10 / 21057447
spleen1 / 5395218
stomach2 / 9661920
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209804_at
Cell line Expression level Expression bar
721_B_lymphoblasts33
Adipocyte7.45
AdrenalCortex8.15
Adrenalgland6.45
Amygdala7.85
Appendix8.35
AtrioventricularNode6.55
BDCA4+_DentriticCells7.65
Bonemarrow7.7
BronchialEpithelialCells7.1
CD105+_Endothelial7.75
CD14+_Monocytes7.8
CD19+_BCells(neg._sel.)7.35
CD33+_Myeloid9.35
CD34+9.3
CD4+_Tcells7.5
CD56+_NKCells9.15
CD71+_EarlyErythroid10.35
CD8+_Tcells6.6
CardiacMyocytes12.5
Caudatenucleus6.65
Cerebellum6.1
CerebellumPeduncles8.6
CiliaryGanglion5.85
CingulateCortex7.7
Colorectaladenocarcinoma7.65
DorsalRootGanglion6.35
FetalThyroid7.3
Fetalbrain7.65
Fetalliver7.25
Fetallung6
GlobusPallidus5.7
Heart11.6
Hypothalamus7.95
Kidney6.2
Leukemia_chronicMyelogenousK-5626.85
Leukemia_promyelocytic-HL-606.65
Leukemialymphoblastic(MOLT-4)5.65
Liver10.35
Lung8.05
Lymphnode6
Lymphoma_burkitts(Daudi)9.75
Lymphoma_burkitts(Raji)11.6
MedullaOblongata6.95
OccipitalLobe6.55
OlfactoryBulb5.85
Ovary5.05
Pancreas6.3
PancreaticIslet8.15
ParietalLobe8.1
Pituitary8.6
Placenta7.2
Pons7.2
PrefrontalCortex9.25
Prostate9.75
Salivarygland6
SkeletalMuscle11.15
Skin6.8
SmoothMuscle8.45
Spinalcord7.7
SubthalamicNucleus6.95
SuperiorCervicalGanglion9.75
TemporalLobe6.95
Testis6.25
TestisGermCell6.2
TestisIntersitial6.4
TestisLeydigCell7.65
TestisSeminiferousTubule6.25
Thalamus7.65
Thymus5.6
Thyroid9.55
Tongue8.1
Tonsil7.4
Trachea5.95
TrigeminalGanglion7.7
Uterus5.9
UterusCorpus7.9
WholeBlood9.3
Wholebrain6.25
colon7.25
pineal_day13.36
pineal_night13.06
retina8.75
small_intestine6.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10693_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.38 ± 0.32
Basal Forebrain5.49 ± 0.13
Basal Part of Pons5.31 ± 0.28
Cerebellar Cortex5.42 ± 0.33
Cerebellar Nuclei5.34 ± 0.54
Claustrum5.46 ± 0.52
Epithalamus5.34 ± 0.35
Frontal Lobe5.31 ± 0.34
Globus Pallidus5 ± 0.37
Hypothalamus5.44 ± 0.26
Insula5.31 ± 0.27
Limbic Lobe5.28 ± 0.43
Mesencephalon5.36 ± 0.39
Myelencephalon5.36 ± 0.38
Occipital Lobe5.63 ± 0.36
Parietal Lobe5.48 ± 0.36
Pontine Tegmentum5.33 ± 0.42
Striatum5.39 ± 0.34
Subthalamus5.42 ± 0.65
Temporal Lobe5.32 ± 0.33
Thalamus5.4 ± 0.35
White Matter4.92 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dclre1aCBCerebellum3.92
4.45
Dclre1aCTXCerebral cortex8
5.75
Dclre1aHIPHippocampal region3.47
3.2
Dclre1aHPFHippocampal formation3.73
3.15
Dclre1aHYHypothalamus0.69
0.7
Dclre1aLSXLateral septal complex0.97
0.71
Dclre1aMBMidbrain1.57
2
Dclre1aMYMedulla3.12
3.08
Dclre1aOLFOlfactory bulb3.91
4.07
Dclre1aPPons1.42
1.43
Dclre1aPALPallidum1.25
1.78
Dclre1aRHPRetrohippocampal region4.37
3.2
Dclre1asAMYStriatum-like amygdalar nuclei1.04
0.7
Dclre1aSTRStriatum1.27
1.14
Dclre1aSTRdStriatum dorsal region1.29
1.21
Dclre1aSTRvStriatum ventral region1.63
1.49
Dclre1aTHThalamus2.27
2.33
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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